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Protein
Submitted name:

Chromobox protein homolog 8

Gene

CBX8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Chromobox protein homolog 8Imported
Gene namesi
Name:CBX8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000141570.10
HGNCiHGNC:15962 CBX8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141570

PTM / Processingi

Proteomic databases

EPDiC9JM54
MaxQBiC9JM54
PeptideAtlasiC9JM54
PRIDEiC9JM54

Expressioni

Gene expression databases

BgeeiENSG00000141570 Expressed in 123 organ(s), highest expression level in right uterine tube
ExpressionAtlasiC9JM54 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JM54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 44ChromoInterPro annotationAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili131 – 155Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IPQ7 Eukaryota
ENOG410XRRX LUCA
GeneTreeiENSGT00530000063056
HOGENOMiHOG000233642

Family and domain databases

CDDicd00024 CHROMO, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR023779 Chromodomain_CS
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 1 hit
SUPFAMiSSF54160 SSF54160, 1 hit
PROSITEiView protein in PROSITE
PS00598 CHROMO_1, 1 hit
PS50013 CHROMO_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

C9JM54-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEYLVKWKGW SQKYSTWEPE ENILDARLLA AFEEREREME LYGPKKRGPK
60 70 80 90 100
PKTFLLKAQA KAKAKTYEFR SDSARGIRIP YPGRSPQDLA STSRAREGLR
110 120 130 140 150
NMGLSPPASS TSTSSTCRAE APRDRDRDRD RDRERDRERE RERERERERE
160 170
RERERGTSRV DDKPSSPGDS SKKRG
Length:175
Mass (Da):20,507
Last modified:July 11, 2012 - v2
Checksum:i2E7358018D4CDDEF
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9HC52CBX8_HUMAN
Chromobox protein homolog 8
CBX8 PC3, RC1
389Annotation score:
C9J6K3C9J6K3_HUMAN
Chromobox protein homolog 8
CBX8
242Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei175Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100791 Genomic DNA No translation available.
AC105337 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000427800; ENSP00000408753; ENSG00000141570
UCSCiuc060kzp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100791 Genomic DNA No translation available.
AC105337 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JM54
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiC9JM54
MaxQBiC9JM54
PeptideAtlasiC9JM54
PRIDEiC9JM54

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000427800; ENSP00000408753; ENSG00000141570
UCSCiuc060kzp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000141570.10
HGNCiHGNC:15962 CBX8
OpenTargetsiENSG00000141570
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IPQ7 Eukaryota
ENOG410XRRX LUCA
GeneTreeiENSGT00530000063056
HOGENOMiHOG000233642

Gene expression databases

BgeeiENSG00000141570 Expressed in 123 organ(s), highest expression level in right uterine tube
ExpressionAtlasiC9JM54 baseline and differential

Family and domain databases

CDDicd00024 CHROMO, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR023779 Chromodomain_CS
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 1 hit
SUPFAMiSSF54160 SSF54160, 1 hit
PROSITEiView protein in PROSITE
PS00598 CHROMO_1, 1 hit
PS50013 CHROMO_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JM54_HUMAN
AccessioniPrimary (citable) accession number: C9JM54
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: July 11, 2012
Last modified: September 12, 2018
This is version 75 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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