UniProtKB - C9JKM9 (C9JKM9_HUMAN)
Protein
Submitted name:
Exportin-1
Gene
XPO1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- Ran GTPase binding Source: InterPro
GO - Biological processi
- intracellular protein transport Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Exportin-1Imported |
Gene namesi | Name:XPO1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000082898.16 |
HGNCi | HGNC:12825, XPO1 |
Subcellular locationi
Expressioni
Gene expression databases
Bgeei | ENSG00000082898, Expressed in female gonad and 252 other tissues |
ExpressionAtlasi | C9JKM9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 112 | Importin N-terminalInterPro annotationAdd BLAST | 67 |
Phylogenomic databases
GeneTreei | ENSGT00940000153408 |
HOGENOMi | CLU_132257_0_0_1 |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR013598, Exportin-1/Importin-b-like IPR001494, Importin-beta_N |
Pfami | View protein in Pfam PF03810, IBN_N, 1 hit PF08389, Xpo1, 1 hit |
SMARTi | View protein in SMART SM00913, IBN_N, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
PROSITEi | View protein in PROSITE PS50166, IMPORTIN_B_NT, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
C9JKM9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAIMTMLAD HAARQLLDFS QKLDINLLDN VVNCLYHGEG AQQRMAQEVL
60 70 80 90 100
THLKEHPDAW TRVDTILEFS QNMNTKYYGL QILENVIKTR WKILPRNQCE
110 120 130 140 150
GIKKYVVGLI IKTSSDPTCV EKEKVYIGKL NMILVQILKQ EWPKHWPTFI
160 170
SDIVGASRTS ESLCQNNMVI LKLLSEEVF
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO14980 | XPO1_HUMAN | Exportin-1 | XPO1 CRM1 | 1,071 | Annotation score: | ||
C9J673 | C9J673_HUMAN | Exportin-1 | XPO1 | 132 | Annotation score: | ||
H7BZC5 | H7BZC5_HUMAN | Exportin-1 | XPO1 | 72 | Annotation score: | ||
C9IZS4 | C9IZS4_HUMAN | Exportin-1 | XPO1 | 94 | Annotation score: | ||
C9JQ02 | C9JQ02_HUMAN | Exportin-1 | XPO1 | 95 | Annotation score: | ||
C9JV99 | C9JV99_HUMAN | Exportin-1 | XPO1 | 100 | Annotation score: | ||
C9IYM2 | C9IYM2_HUMAN | Exportin-1 | XPO1 | 62 | Annotation score: | ||
C9JF49 | C9JF49_HUMAN | Exportin-1 | XPO1 | 59 | Annotation score: | ||
F8WF71 | F8WF71_HUMAN | Exportin-1 | XPO1 | 82 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 179 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016727 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000451765; ENSP00000413853; ENSG00000082898 |
UCSCi | uc061jol.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016727 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | C9JKM9 |
PeptideAtlasi | C9JKM9 |
ProteomicsDBi | 10596 |
Protocols and materials databases
Antibodypediai | 4124, 345 antibodies |
Genome annotation databases
Ensembli | ENST00000451765; ENSP00000413853; ENSG00000082898 |
UCSCi | uc061jol.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000082898.16 |
HGNCi | HGNC:12825, XPO1 |
OpenTargetsi | ENSG00000082898 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153408 |
HOGENOMi | CLU_132257_0_0_1 |
Miscellaneous databases
ChiTaRSi | XPO1, human |
Gene expression databases
Bgeei | ENSG00000082898, Expressed in female gonad and 252 other tissues |
ExpressionAtlasi | C9JKM9, baseline and differential |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR013598, Exportin-1/Importin-b-like IPR001494, Importin-beta_N |
Pfami | View protein in Pfam PF03810, IBN_N, 1 hit PF08389, Xpo1, 1 hit |
SMARTi | View protein in SMART SM00913, IBN_N, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
PROSITEi | View protein in PROSITE PS50166, IMPORTIN_B_NT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JKM9_HUMAN | |
Accessioni | C9JKM9Primary (citable) accession number: C9JKM9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | October 7, 2020 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |