UniProtKB - C9JKD9 (C9JKD9_HUMAN)
Protein
Submitted name:
ATP-binding cassette sub-family G member 1
Gene
ABCG1
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 118 – 125 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-UniRule
- cholesterol transfer activity Source: InterPro
GO - Biological processi
- intracellular cholesterol transport Source: InterPro
Keywordsi
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: ATP-binding cassette sub-family G member 1Imported |
Gene namesi | Name:ABCG1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:73, ABCG1 |
VEuPathDBi | HostDB:ENSG00000160179.18 |
Subcellular locationi
Other locations
- integral component of membrane Source: InterPro
PTM / Processingi
Proteomic databases
MaxQBi | C9JKD9 |
PeptideAtlasi | C9JKD9 |
PRIDEi | C9JKD9 |
ProteomicsDBi | 10569 |
Expressioni
Gene expression databases
Bgeei | ENSG00000160179, Expressed in right adrenal gland cortex and 224 other tissues |
ExpressionAtlasi | C9JKD9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 77 – 257 | ABC transporterInterPro annotationAdd BLAST | 181 |
Phylogenomic databases
GeneTreei | ENSGT00940000160131 |
HOGENOMi | CLU_000604_1_10_1 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR020064, ABCG1 IPR027417, P-loop_NTPase |
PANTHERi | PTHR48041:SF90, PTHR48041:SF90, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
C9JKD9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MACLMAAFSV GTAMNASSYS AEMTEPKSVC VSVDEVVSSN MEATETDLLN
60 70 80 90 100
GHLKKVDNNL TEAQRFSSLP RRAAVNIEFR DLSYSVPEGP WWRKKGYKTL
110 120 130 140 150
LKGISGKFNS GELVAIMGPS GAGKSTLMNI LAGYRETGMK GAVLINGLPR
160 170 180 190 200
DLRCFRKVSC YIMQDDMLLP HLTVQEAMMV KEILTALGLL SCANTRTGSL
210 220 230 240 250
SGGQRKRLAI ALELVNNPPV MFFDEPTSGL DSASCFQVVS LMKGLAQGGR
SIICTIH
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP45844 | ABCG1_HUMAN | ATP-binding cassette sub-family G m... | ABCG1 ABC8, WHT1 | 678 | Annotation score: | ||
E9PGV9 | E9PGV9_HUMAN | ATP-binding cassette sub-family G m... | ABCG1 | 824 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 257 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001622 Genomic DNA No translation available. AP001623 Genomic DNA No translation available. KC877901 Genomic DNA No translation available. KC877905 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000450121; ENSP00000414541; ENSG00000160179 |
UCSCi | uc062akl.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001622 Genomic DNA No translation available. AP001623 Genomic DNA No translation available. KC877901 Genomic DNA No translation available. KC877905 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | C9JKD9 |
PeptideAtlasi | C9JKD9 |
PRIDEi | C9JKD9 |
ProteomicsDBi | 10569 |
Protocols and materials databases
Antibodypediai | 23734, 389 antibodies |
Genome annotation databases
Ensembli | ENST00000450121; ENSP00000414541; ENSG00000160179 |
UCSCi | uc062akl.1, human |
Organism-specific databases
HGNCi | HGNC:73, ABCG1 |
OpenTargetsi | ENSG00000160179 |
VEuPathDBi | HostDB:ENSG00000160179.18 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000160131 |
HOGENOMi | CLU_000604_1_10_1 |
Miscellaneous databases
ChiTaRSi | ABCG1, human |
Gene expression databases
Bgeei | ENSG00000160179, Expressed in right adrenal gland cortex and 224 other tissues |
ExpressionAtlasi | C9JKD9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR020064, ABCG1 IPR027417, P-loop_NTPase |
PANTHERi | PTHR48041:SF90, PTHR48041:SF90, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9JKD9_HUMAN | |
Accessioni | C9JKD9Primary (citable) accession number: C9JKD9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |