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Protein

Transmembrane protein 238

Gene

TMEM238

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 238
Gene namesi
Name:TMEM238
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000233493.3
HGNCiHGNC:40042 TMEM238
neXtProtiNX_C9JI98

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 36CytoplasmicSequence analysisAdd BLAST36
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Topological domaini58 – 69ExtracellularSequence analysisAdd BLAST12
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Topological domaini91 – 176CytoplasmicSequence analysisAdd BLAST86

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135401 – 176Transmembrane protein 238Add BLAST176

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei175PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiC9JI98
MaxQBiC9JI98
PaxDbiC9JI98
PRIDEiC9JI98
ProteomicsDBi10307

PTM databases

iPTMnetiC9JI98
PhosphoSitePlusiC9JI98

Expressioni

Gene expression databases

BgeeiENSG00000233493

Structurei

3D structure databases

ProteinModelPortaliC9JI98
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 51Ala-richAdd BLAST50

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J41J Eukaryota
ENOG410YPH6 LUCA
GeneTreeiENSGT00390000013421
HOGENOMiHOG000169144
InParanoidiC9JI98
OMAiGLGRCVC
OrthoDBiEOG091G12QS
PhylomeDBiC9JI98
TreeFamiTF339060

Family and domain databases

InterProiView protein in InterPro
IPR029365 TMEM238
PfamiView protein in Pfam
PF15125 TMEM238, 1 hit

Sequencei

Sequence statusi: Complete.

C9JI98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAPAVCAS QGSPPGAPSA PAAAPAPAAG LGRCRMALLL AVALDVAGMA
60 70 80 90 100
ALLTGVFAQL QVRGRDFGDL LIYSGALLVF LSLLGWILWY TGNIEISRQE
110 120 130 140 150
LERDYGLRPS ALARLARKLS RRWSAPAAAG QRPAPGSRRA RRAARAPPPP
160 170
AAGSRRVRLQ LATLEAGPGA AGAGSE
Length:176
Mass (Da):18,040
Last modified:November 3, 2009 - v1
Checksum:i323ABC220EC3506C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti14P → S in BC052596 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020922 Genomic DNA No translation available.
BC052596 mRNA No translation available.
CCDSiCCDS54323.1
RefSeqiNP_001177693.1, NM_001190764.1
UniGeneiHs.534672

Genome annotation databases

EnsembliENST00000444469; ENSP00000416154; ENSG00000233493
GeneIDi388564
KEGGihsa:388564
UCSCiuc002qku.4 human

Similar proteinsi

Entry informationi

Entry nameiTM238_HUMAN
AccessioniPrimary (citable) accession number: C9JI98
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 3, 2009
Last modified: July 18, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM

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