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UniProtKB - C9JH25 (PRRT4_HUMAN)

Entry version 77 (10 Feb 2021)
Sequence version 1 (03 Nov 2009)
Previous versions | rss
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Protein

Proline-rich transmembrane protein 4

Gene

PRRT4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		C9JH25

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Proline-rich transmembrane protein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRRT4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:37280, PRRT4

neXtProt; the human protein knowledge platform

More...neXtProti		NX_C9JH25

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000224940.8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Transmembranei392 – 412HelicalSequence analysisAdd BLAST21
Transmembranei430 – 450HelicalSequence analysisAdd BLAST21
Transmembranei467 – 487HelicalSequence analysisAdd BLAST21
Transmembranei500 – 520HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000224940

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA165618245

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		C9JH25, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		PRRT4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000039449824 – 899Proline-rich transmembrane protein 4Add BLAST876

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei641PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		C9JH25

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		C9JH25

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		C9JH25

PeptideAtlas

More...PeptideAtlasi		C9JH25

PRoteomics IDEntifications database

More...PRIDEi		C9JH25

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		10169 [C9JH25-1]
10170 [C9JH25-2]
10171 [C9JH25-3]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		C9JH25, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		C9JH25

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		C9JH25

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000224940, Expressed in bone marrow and 103 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		C9JH25, baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000224940, Tissue enriched (bone)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		135071, 6 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000415026

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		C9JH25, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi373 – 516Leu-richAdd BLAST144
Compositional biasi522 – 525Poly-Arg4
Compositional biasi799 – 862Ser-richAdd BLAST64

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QU49, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00730000111591

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_351937_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		C9JH25

Identification of Orthologs from Complete Genome Data

More...OMAi		CALAEPG

Database of Orthologous Groups

More...OrthoDBi		921831at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		C9JH25

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR043542, Prrt4-like

The PANTHER Classification System

More...PANTHERi		PTHR35578:SF1, PTHR35578:SF1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: C9JH25-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MARHGCLGLG LFCCVLFAAT VGPQPTPSIP GAPATTLTPV PQSEASMLSL 
        60         70         80         90        100
NLGLNFKFHL RGPAAVWGSP VTETQPLSLG PGQEPGEEVA SGLRTDPLWE 
       110        120        130        140        150
LLVGSSGNSL TEWGSTEGGS KPRASSLLPE STSRRSGPSD GPTAPYQPRR 
       160        170        180        190        200
STVTWDTALM VTALPSSAPR PHQSELELKF DMALRAGAAP TLGHRTLPLL 
       210        220        230        240        250
PSLRASLAEI AGRLGPFGFF GTTLSPLRNF SGLSPPGETT STSSASGVSG 
       260        270        280        290        300
SLGFLGTTLS LPPYSLERKL SSPSPLDPAA SLSFASIATT SLDPTVPISG 
       310        320        330        340        350
PDDLSPPASL GNPSGQPECG PGSCSVGELP EREGQPPEAP RPLFFLTLEA 
       360        370        380        390        400
DWAEARARWG LAWEAHVYGV GALFGLVALL ALLALALLPW RCPPGAPCLA 
       410        420        430        440        450
LLDLLLLSAG TTRAFPLFYD AYGHRDRLPA LAWLLLQDLP LPCLAAGLGL 
       460        470        480        490        500
ACLLLARPRP PRCPTGLAAL LLLGLGLAAA AALGSAAHRP LRPLRLASRG 
       510        520        530        540        550
LHAFLAAFLS GLLLALSCWG GRRRRAGAPL GGSGFKGATP LPQGRSPFAP 
       560        570        580        590        600
RESWRRAART APVAGTFGLL SGALQGYEVL HALGYGGQSG LEGPWPWWAF 
       610        620        630        640        650
QLGLRLGEVG VALPLALLGL YPALCSPRVP PRCWAKLFRL SPGHAAPLLP 
       660        670        680        690        700
GGWVTGPPDK EPLGSAIARG DAELLQLCAL AGPGPDLLLQ GGGCRGFEGA 
       710        720        730        740        750
AANPAPSPAS SPCSDYTVDF RPPSPINLRR SIEEALCSEA LLAPGLFQGP 
       760        770        780        790        800
AFEDALPGLG LYRTASLGTG GRASERSGEA SGPAAPPELP SPGAWPAGSS 
       810        820        830        840        850
VSSGSFCGLS RDSSSMLLCS SPDRPPRCPL VCVLSPPRPS GSSPSLPASG 
       860        870        880        890 
SYQALSPPSR DSPEPASELQ AEEALLQEQF LDACRQIDEL SVGSDTIDL
Length:899
Mass (Da):92,712
Last modified:November 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4E03C2B27A57A772
GO
Isoform 2 (identifier: C9JH25-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     370-429: VGALFGLVAL...DAYGHRDRLP → RLHRGLPPAL...RLAGDRGQGQ
     430-899: Missing.

Show »
Length:429
Mass (Da):44,619
Checksum:i54A71469006E9AD9
GO
Isoform 3 (identifier: C9JH25-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     370-575: Missing.

Show »
Length:693
Mass (Da):71,439
Checksum:i131E4612BB56FC8F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JVX5C9JVX5_HUMAN
HCG1651889, isoform CRA_d
PRRT4 hCG_1651889
479Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JQT1C9JQT1_HUMAN
Proline-rich transmembrane protein ...
PRRT4
208Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JWH6C9JWH6_HUMAN
Proline-rich transmembrane protein ...
PRRT4
205Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C4Q3H7C4Q3_HUMAN
Proline-rich transmembrane protein ...
PRRT4
419Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_039274370 – 575Missing in isoform 3. CuratedAdd BLAST206
Alternative sequenceiVSP_039273370 – 429VGALF…RDRLP → RLHRGLPPALPNQPATQHRG GPLQRGPACAWPLPGPCLRG RSAWARTLPHRLAGDRGQGQ in isoform 2. 1 PublicationAdd BLAST60
Alternative sequenceiVSP_039275430 – 899Missing in isoform 2. 1 PublicationAdd BLAST470

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC010655 Genomic DNA No translation available.
CH236947 Genomic DNA Translation: EAL24313.1
CH471070 Genomic DNA Translation: EAW83645.1
BC063892 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS47698.2 [C9JH25-2]
CCDS55160.1 [C9JH25-1]

NCBI Reference Sequences

More...RefSeqi		NP_001108198.2, NM_001114726.2 [C9JH25-2]
NP_001167635.1, NM_001174164.1 [C9JH25-1]
XP_005250399.1, XM_005250342.3 [C9JH25-1]
XP_005250400.1, XM_005250343.3 [C9JH25-1]
XP_006716048.1, XM_006715985.3 [C9JH25-1]
XP_016867694.1, XM_017012205.1 [C9JH25-1]
XP_016867695.1, XM_017012206.1 [C9JH25-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000446477; ENSP00000415026; ENSG00000224940 [C9JH25-1]
ENST00000489835; ENSP00000419296; ENSG00000224940 [C9JH25-2]
ENST00000535159; ENSP00000445239; ENSG00000224940 [C9JH25-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		401399

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:401399

UCSC genome browser

More...UCSCi		uc022akx.2, human [C9JH25-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010655 Genomic DNA No translation available.
CH236947 Genomic DNA Translation: EAL24313.1
CH471070 Genomic DNA Translation: EAW83645.1
BC063892 mRNA No translation available.
CCDSiCCDS47698.2 [C9JH25-2]
CCDS55160.1 [C9JH25-1]
RefSeqiNP_001108198.2, NM_001114726.2 [C9JH25-2]
NP_001167635.1, NM_001174164.1 [C9JH25-1]
XP_005250399.1, XM_005250342.3 [C9JH25-1]
XP_005250400.1, XM_005250343.3 [C9JH25-1]
XP_006716048.1, XM_006715985.3 [C9JH25-1]
XP_016867694.1, XM_017012205.1 [C9JH25-1]
XP_016867695.1, XM_017012206.1 [C9JH25-2]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi135071, 6 interactors
STRINGi9606.ENSP00000415026

PTM databases

GlyGeniC9JH25, 1 site, 1 O-linked glycan (1 site)
iPTMnetiC9JH25
PhosphoSitePlusiC9JH25

Genetic variation databases

BioMutaiPRRT4

Proteomic databases

jPOSTiC9JH25
MassIVEiC9JH25
PaxDbiC9JH25
PeptideAtlasiC9JH25
PRIDEiC9JH25
ProteomicsDBi10169 [C9JH25-1]
10170 [C9JH25-2]
10171 [C9JH25-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		67265, 69 antibodies

Genome annotation databases

EnsembliENST00000446477; ENSP00000415026; ENSG00000224940 [C9JH25-1]
ENST00000489835; ENSP00000419296; ENSG00000224940 [C9JH25-2]
ENST00000535159; ENSP00000445239; ENSG00000224940 [C9JH25-1]
GeneIDi401399
KEGGihsa:401399
UCSCiuc022akx.2, human [C9JH25-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		401399

GeneCards: human genes, protein and diseases

More...GeneCardsi		PRRT4
HGNCiHGNC:37280, PRRT4
HPAiENSG00000224940, Tissue enriched (bone)
neXtProtiNX_C9JH25
OpenTargetsiENSG00000224940
PharmGKBiPA165618245
VEuPathDBiHostDB:ENSG00000224940.8

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QU49, Eukaryota
GeneTreeiENSGT00730000111591
HOGENOMiCLU_351937_0_0_1
InParanoidiC9JH25
OMAiCALAEPG
OrthoDBi921831at2759
PhylomeDBiC9JH25

Enzyme and pathway databases

PathwayCommonsiC9JH25

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		401399, 12 hits in 874 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		PRRT4, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		401399
PharosiC9JH25, Tdark

Protein Ontology

More...PROi		PR:C9JH25
RNActiC9JH25, protein

Gene expression databases

BgeeiENSG00000224940, Expressed in bone marrow and 103 other tissues
ExpressionAtlasiC9JH25, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR043542, Prrt4-like
PANTHERiPTHR35578:SF1, PTHR35578:SF1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRRT4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C9JH25
Secondary accession number(s): A4D0Z9, C9JVW7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: November 3, 2009
Last modified: February 10, 2021
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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