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Protein
Submitted name:

C-X-C chemokine receptor type 2

Gene

CXCR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
C-X-C chemokine receptor type 2Imported
Gene namesi
Name:CXCR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000180871.7
HGNCiHGNC:6027 CXCR2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 74HelicalSequence analysisAdd BLAST26
Transmembranei86 – 105HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000180871

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JG19
PRIDEiC9JG19

Expressioni

Gene expression databases

BgeeiENSG00000180871
ExpressionAtlasiC9JG19 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliC9JG19
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 135G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST71

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEHI Eukaryota
ENOG410Y9Y6 LUCA
GeneTreeiENSGT00760000118785

Family and domain databases

InterProiView protein in InterPro
IPR000057 Chemokine_CXCR2
IPR000174 Chemokine_CXCR_1/2
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00427 INTRLEUKIN8R
PR00573 INTRLEUKN8BR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Fragment.

C9JG19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDFNMESDS FEDFWKGEDL SNYSYSSTLP PFLLDAAPCE PESLEINKYF
60 70 80 90 100
VVIIYALVFL LSLLGNSLVM LVILYSRVGR SVTDVYLLNL ALADLLFALT
110 120 130
LPIWAASKVN GWIFGTFLCK VVSLLKEVNF YSGIL
Length:135
Mass (Da):15,212
Last modified:October 5, 2016 - v8
Checksum:iF4BD116B2A52F56F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei135Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124768 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000454148; ENSP00000415148; ENSG00000180871
UCSCiuc061sib.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JG19_HUMAN
AccessioniPrimary (citable) accession number: C9JG19
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 61 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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