Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Septin-2

Gene

SEPT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Septin-2Imported
Gene namesi
Name:SEPT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000168385.17
HGNCiHGNC:7729 SEPT2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168385

PTM / Processingi

Proteomic databases

MaxQBiC9JFT1
PeptideAtlasiC9JFT1
PRIDEiC9JFT1

Expressioni

Gene expression databases

BgeeiENSG00000168385 Expressed in 238 organ(s), highest expression level in metanephros
ExpressionAtlasiC9JFT1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JFT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 72Septin-type GInterPro annotationAdd BLAST39

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG2655 Eukaryota
COG5019 LUCA
GeneTreeiENSGT00910000144020

Family and domain databases

InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00735 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 19 potential isoforms that are computationally mapped.Show allAlign All

C9JFT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK
60 70
STLINSLFLT DLYPERVIPG AA
Length:72
Mass (Da):7,896
Last modified:November 3, 2009 - v1
Checksum:i937E6F25D384F9B0
GO

Computationally mapped potential isoform sequencesi

There are 19 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q15019SEPT2_HUMAN
Septin-2
SEPT2 DIFF6, KIAA0158, NEDD5
361Annotation score:
B5MCX3B5MCX3_HUMAN
Septin-2
SEPT2
321Annotation score:
C9J2Q4C9J2Q4_HUMAN
Septin-2
SEPT2
184Annotation score:
H7C2Y0H7C2Y0_HUMAN
Septin-2
SEPT2
188Annotation score:
C9JQJ4C9JQJ4_HUMAN
Septin-2
SEPT2
147Annotation score:
C9JZI2C9JZI2_HUMAN
Septin-2
SEPT2
105Annotation score:
C9IY94C9IY94_HUMAN
Septin-2
SEPT2
121Annotation score:
C9IZU3C9IZU3_HUMAN
Septin-2
SEPT2
131Annotation score:
F8WB65F8WB65_HUMAN
Septin-2
SEPT2
80Annotation score:
C9JB25C9JB25_HUMAN
Septin-2
SEPT2
173Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei72Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005104 Genomic DNA No translation available.
AC104841 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000445030; ENSP00000404484; ENSG00000168385
UCSCiuc061uoo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005104 Genomic DNA No translation available.
AC104841 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JFT1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JFT1
PeptideAtlasiC9JFT1
PRIDEiC9JFT1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000445030; ENSP00000404484; ENSG00000168385
UCSCiuc061uoo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168385.17
HGNCiHGNC:7729 SEPT2
OpenTargetsiENSG00000168385
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2655 Eukaryota
COG5019 LUCA
GeneTreeiENSGT00910000144020

Miscellaneous databases

ChiTaRSiSEPT2 human

Gene expression databases

BgeeiENSG00000168385 Expressed in 238 organ(s), highest expression level in metanephros
ExpressionAtlasiC9JFT1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00735 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JFT1_HUMAN
AccessioniPrimary (citable) accession number: C9JFT1
Secondary accession number(s): A0A0A6YYT9, A0A0K0K1E7, C9JTV8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again