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Protein
Submitted name:

Vesicle-trafficking protein SEC22a

Gene

SEC22A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Vesicle-trafficking protein SEC22aImported
Gene namesi
Name:SEC22AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000121542.11
HGNCiHGNC:20260 SEC22A

Subcellular locationi

Keywords - Cellular componenti

MembraneSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000121542

PTM / Processingi

Proteomic databases

MaxQBiC9JDJ8
PeptideAtlasiC9JDJ8
PRIDEiC9JDJ8

Expressioni

Gene expression databases

BgeeiENSG00000121542 Expressed in 196 organ(s), highest expression level in kidney
ExpressionAtlasiC9JDJ8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JDJ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 119LonginInterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the synaptobrevin family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0862 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00510000046833
HOGENOMiHOG000007733

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR027152 Sec22a
PANTHERiPTHR21136:SF68 PTHR21136:SF68, 1 hit
PfamiView protein in Pfam
PF13774 Longin, 1 hit
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

C9JDJ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSMILSASVI RVRDGLPLSA STDYEQSTGM QECRKYFKML SRKLAQLPDR
60 70 80 90 100
CTLKTGHYNI NFISSLGVSY MMLCTENYPN VLAFSFLDEL QKEFITTYNM
110 120 130
MKTNTAVRPY CFIEFDNFIQ RTKQRYNNPR SLSTKINL
Length:138
Mass (Da):16,090
Last modified:November 3, 2009 - v1
Checksum:i32716D076C1136BE
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96IW7SC22A_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A SEC22L2
307Annotation score:
C9JNZ0C9JNZ0_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A
288Annotation score:
C9JRY4C9JRY4_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A
218Annotation score:
C9J463C9J463_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A
101Annotation score:
C9JZ27C9JZ27_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A
108Annotation score:
F8WAU7F8WAU7_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A
71Annotation score:
C9JR77C9JR77_HUMAN
Vesicle-trafficking protein SEC22a
SEC22A
99Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei138Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063922 Genomic DNA No translation available.
AC112503 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000480631; ENSP00000420574; ENSG00000121542
UCSCiuc062nbw.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063922 Genomic DNA No translation available.
AC112503 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JDJ8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9JDJ8
PeptideAtlasiC9JDJ8
PRIDEiC9JDJ8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000480631; ENSP00000420574; ENSG00000121542
UCSCiuc062nbw.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000121542.11
HGNCiHGNC:20260 SEC22A
OpenTargetsiENSG00000121542
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0862 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00510000046833
HOGENOMiHOG000007733

Miscellaneous databases

ChiTaRSiSEC22A human

Gene expression databases

BgeeiENSG00000121542 Expressed in 196 organ(s), highest expression level in kidney
ExpressionAtlasiC9JDJ8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR027152 Sec22a
PANTHERiPTHR21136:SF68 PTHR21136:SF68, 1 hit
PfamiView protein in Pfam
PF13774 Longin, 1 hit
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JDJ8_HUMAN
AccessioniPrimary (citable) accession number: C9JDJ8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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