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Protein
Submitted name:

Low affinity immunoglobulin gamma Fc region receptor III-A

Gene

FCGR3A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Low affinity immunoglobulin gamma Fc region receptor III-AImported
Gene namesi
Name:FCGR3AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000203747.9
HGNCiHGNC:3619 FCGR3A

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203747

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500299654017 – 105Sequence analysisAdd BLAST89

Proteomic databases

PeptideAtlasiC9JC71
PRIDEiC9JC71

Expressioni

Gene expression databases

BgeeiENSG00000203747 Expressed in 91 organ(s), highest expression level in leukocyte
ExpressionAtlasiC9JC71 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JC71
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 104Ig-likeInterPro annotationAdd BLAST82

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IKYD Eukaryota
ENOG41114N1 LUCA
GeneTreeiENSGT00760000119130
HOGENOMiHOG000251632

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
PfamiView protein in Pfam
PF13895 Ig_2, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

C9JC71-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWQLLLPTAL LLLVSAGMRT DLPKAVVFLE PQWYRVLEKD SVTLKCQGAY
60 70 80 90 100
SPEDNSTQWF HNESLISSQA SSYFIDAATV DDSGEYRCQT NLSTLSDPVQ

LEVHI
Length:105
Mass (Da):11,823
Last modified:November 3, 2009 - v1
Checksum:i880466486E0C35FB
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P08637FCG3A_HUMAN
Low affinity immunoglobulin gamma F...
FCGR3A CD16A, FCG3, FCGR3, IGFR3
254Annotation score:
M9MML0M9MML0_HUMAN
Low affinity immunoglobulin gamma F...
FCGR3A
359Annotation score:
H0Y755H0Y755_HUMAN
Low affinity immunoglobulin gamma F...
FCGR3A
307Annotation score:
A0A1W2PQB1A0A1W2PQB1_HUMAN
Fc of IgG low affinity IIIa recepto...
FCGR3A
290Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei105Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590385 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000442336; ENSP00000396567; ENSG00000203747
UCSCiuc057mso.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590385 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JC71
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9JC71
PRIDEiC9JC71

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000442336; ENSP00000396567; ENSG00000203747
UCSCiuc057mso.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000203747.9
HGNCiHGNC:3619 FCGR3A
OpenTargetsiENSG00000203747
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IKYD Eukaryota
ENOG41114N1 LUCA
GeneTreeiENSGT00760000119130
HOGENOMiHOG000251632

Miscellaneous databases

ChiTaRSiFCGR3A human

Gene expression databases

BgeeiENSG00000203747 Expressed in 91 organ(s), highest expression level in leukocyte
ExpressionAtlasiC9JC71 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
PfamiView protein in Pfam
PF13895 Ig_2, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JC71_HUMAN
AccessioniPrimary (citable) accession number: C9JC71
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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