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Protein
Submitted name:

Voltage-dependent calcium channel subunit alpha-2/delta-3

Gene

CACNA2D3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent calcium channel subunit alpha-2/delta-3Imported
Gene namesi
Name:CACNA2D3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000157445.14
HGNCiHGNC:15460 CACNA2D3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157445

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JAV5
PRIDEiC9JAV5

Expressioni

Gene expression databases

BgeeiENSG00000157445 Expressed in 163 organ(s), highest expression level in caudate nucleus
ExpressionAtlasiC9JAV5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JAV5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 126VWA_NInterPro annotationAdd BLAST108

Phylogenomic databases

eggNOGiKOG2353 Eukaryota
ENOG410XPDX LUCA
GeneTreeiENSGT00530000062904
HOGENOMiHOG000010247

Family and domain databases

InterProiView protein in InterPro
IPR013608 VWA_N
PfamiView protein in Pfam
PF08399 VWA_N, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

C9JAV5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEMFHKKSE AVRRLVEAAE EAHLKHEFDA DLQYEYFNAV LINERDKDGN
60 70 80 90 100
FLELGKEFIL APNDHFNNLP VNISLSDVQV PTNMYNKDPA IVNGVYWSES
110 120
LNKVFVDNFD RDPSLIWQYF GSAKGF
Length:126
Mass (Da):14,647
Last modified:November 3, 2009 - v1
Checksum:i2589D93080C8D92F
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8IZS8CA2D3_HUMAN
Voltage-dependent calcium channel s...
CACNA2D3
1,091Annotation score:
B4DSF6B4DSF6_HUMAN
Voltage-dependent calcium channel s...
CACNA2D3
525Annotation score:
F8WAV4F8WAV4_HUMAN
Voltage-dependent calcium channel s...
CACNA2D3
46Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei126Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092057 Genomic DNA No translation available.
AC092797 Genomic DNA No translation available.
AC109581 Genomic DNA No translation available.
AC109584 Genomic DNA No translation available.
AC115282 Genomic DNA No translation available.
AC133010 Genomic DNA No translation available.
AC137673 Genomic DNA No translation available.
AC138059 Genomic DNA No translation available.
KF457637 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000492460; ENSP00000418028; ENSG00000157445
UCSCiuc062ktl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092057 Genomic DNA No translation available.
AC092797 Genomic DNA No translation available.
AC109581 Genomic DNA No translation available.
AC109584 Genomic DNA No translation available.
AC115282 Genomic DNA No translation available.
AC133010 Genomic DNA No translation available.
AC137673 Genomic DNA No translation available.
AC138059 Genomic DNA No translation available.
KF457637 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9JAV5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9JAV5
PRIDEiC9JAV5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000492460; ENSP00000418028; ENSG00000157445
UCSCiuc062ktl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000157445.14
HGNCiHGNC:15460 CACNA2D3
OpenTargetsiENSG00000157445
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2353 Eukaryota
ENOG410XPDX LUCA
GeneTreeiENSGT00530000062904
HOGENOMiHOG000010247

Miscellaneous databases

ChiTaRSiCACNA2D3 human

Gene expression databases

BgeeiENSG00000157445 Expressed in 163 organ(s), highest expression level in caudate nucleus
ExpressionAtlasiC9JAV5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013608 VWA_N
PfamiView protein in Pfam
PF08399 VWA_N, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9JAV5_HUMAN
AccessioniPrimary (citable) accession number: C9JAV5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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