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Protein
Submitted name:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Gene

PIK3CA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformImported
Gene namesi
Name:PIK3CAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000121879.3
HGNCiHGNC:8975 PIK3CA

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000121879

PTM / Processingi

Proteomic databases

MaxQBiC9JAM9
PeptideAtlasiC9JAM9
PRIDEiC9JAM9

Expressioni

Gene expression databases

BgeeiENSG00000121879
ExpressionAtlasiC9JAM9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JAM9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 105PI3K-ABDInterPro annotationAdd BLAST90

Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0904 Eukaryota
COG5032 LUCA
GeneTreeiENSGT00760000119110
HOGENOMiHOG000200034

Family and domain databases

InterProiView protein in InterPro
IPR003113 PI3K_adapt-bd_dom
IPR015433 PI_Kinase
PANTHERiPTHR10048 PTHR10048, 1 hit
PfamiView protein in Pfam
PF02192 PI3K_p85B, 1 hit
SMARTiView protein in SMART
SM00143 PI3K_p85B, 1 hit
PROSITEiView protein in PROSITE
PS51544 PI3K_ABD, 1 hit

Sequencei

Sequence statusi: Fragment.

C9JAM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPRPSSGEL WGIHLMPPRI LVECLLPNGM IVTLECLREA TLITIKHELF
60 70 80 90 100
KEARKYPLHQ LLQDESSYIF VSVTQEAERE EFFDETRRLC DLRLFQPFLK
110
VIEPVGNREE KILNREIG
Length:118
Mass (Da):13,847
Last modified:November 3, 2009 - v1
Checksum:i34775C6319A88543
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei118Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC076966 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000468036; ENSP00000417479; ENSG00000121879
UCSCiuc062qdy.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JAM9_HUMAN
AccessioniPrimary (citable) accession number: C9JAM9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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