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Protein
Submitted name:

V-type proton ATPase catalytic subunit A

Gene

ATP6V1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
V-type proton ATPase catalytic subunit AImported
Gene namesi
Name:ATP6V1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000114573.9
HGNCiHGNC:851 ATP6V1A

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000114573

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JA17
PRIDEiC9JA17

Expressioni

Gene expression databases

BgeeiENSG00000114573 Expressed in 238 organ(s), highest expression level in Brodmann (1909) area 23
ExpressionAtlasiC9JA17 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JA17
SMRiC9JA17
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 50ATP-synt_ab_NInterPro annotationAdd BLAST47
Domaini66 – 184ATP-synt_ab_XtnInterPro annotationAdd BLAST119

Phylogenomic databases

eggNOGiKOG1352 Eukaryota
COG1155 LUCA
GeneTreeiENSGT00550000074787
HOGENOMiHOG000161057

Family and domain databases

InterProiView protein in InterPro
IPR031686 ATP-synth_a_Xtn
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR022878 V-ATPase_asu
PANTHERiPTHR43607 PTHR43607, 1 hit
PfamiView protein in Pfam
PF02874 ATP-synt_ab_N, 1 hit
PF16886 ATP-synt_ab_Xtn, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

C9JA17-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGAAMYELV RVGHSELVGE IIRLEGDMAT IQVYEETSGV SVGDPVLRTG
60 70 80 90 100
KPLSVELGPG IMGAIFDGIQ RPLSDISSQT QSIYIPRGVN VSALSRDIKW
110 120 130 140 150
DFTPCKNLRV GSHITGGDIY GIVSENSLIK HKIMLPPRNR GTVTYIAPPG
160 170 180
NYDTSDVVLE LEFEGVKEKF TMVQVWPVRQ VRPV
Length:184
Mass (Da):20,140
Last modified:October 5, 2016 - v8
Checksum:iACC63B16EEB9DAF4
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P38606VATA_HUMAN
V-type proton ATPase catalytic subu...
ATP6V1A ATP6A1, ATP6V1A1, VPP2
617Annotation score:
C9JVW8C9JVW8_HUMAN
V-type proton ATPase catalytic subu...
ATP6V1A
221Annotation score:
F8WDJ3F8WDJ3_HUMAN
V-type proton ATPase catalytic subu...
ATP6V1A
49Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei184Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079944 Genomic DNA No translation available.
AC108693 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000496747; ENSP00000417545; ENSG00000114573
UCSCiuc062mox.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JA17_HUMAN
AccessioniPrimary (citable) accession number: C9JA17
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 64 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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