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Protein
Submitted name:

Receptor-type tyrosine-protein phosphatase delta

Gene

PTPRD

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor-type tyrosine-protein phosphatase deltaImported
Gene namesi
Name:PTPRDImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000153707.15
HGNCiHGNC:9668 PTPRD

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000153707

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501456945021 – 202Sequence analysisAdd BLAST182

Proteomic databases

MaxQBiC9J8S8
PRIDEiC9J8S8

Expressioni

Gene expression databases

BgeeiENSG00000153707 Expressed in 196 organ(s), highest expression level in forebrain
ExpressionAtlasiC9J8S8 baseline and differential

Structurei

3D structure databases

SMRiC9J8S8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 114Ig-likeInterPro annotationAdd BLAST91
Domaini126 – 162Ig-likeInterPro annotationAdd BLAST37

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4228 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00760000118900
HOGENOMiHOG000286012

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF07679 I-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

C9J8S8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVHVARLLLL LLTFFLRTDA ETPPRFTRTP VDQTGVSGGV ASFICQATGD
60 70 80 90 100
PRPKIVWNKK GKKVSNQRFE VIEFDDGSGS VLRIQPLRTP RDEAIYECVA
110 120 130 140 150
SNNVGEISVS TRLTVLREDQ IPRGFPTIDM GPQLKVVERT RTATMLCAAS
160 170 180 190 200
GNPDPEITWF KDFLPVDTSN NNGRIKQLRS GTDFSPSSLS LLLNGWSMFV

MS
Length:202
Mass (Da):22,417
Last modified:November 3, 2009 - v1
Checksum:iC8B5BCCBA98BA800
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P23468PTPRD_HUMAN
Receptor-type tyrosine-protein phos...
PTPRD
1,912Annotation score:
Q3KPI9Q3KPI9_HUMAN
PTPRD protein
PTPRD
1,496Annotation score:
F5GWR7F5GWR7_HUMAN
Receptor-type tyrosine-protein phos...
PTPRD
1,505Annotation score:
A0A1B0GU15A0A1B0GU15_HUMAN
Receptor-type tyrosine-protein phos...
PTPRD
297Annotation score:
C9J6E4C9J6E4_HUMAN
Receptor-type tyrosine-protein phos...
PTPRD
93Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC245202 Genomic DNA No translation available.
AL137125 Genomic DNA No translation available.
AL353638 Genomic DNA No translation available.
AL356584 Genomic DNA No translation available.
AL445926 Genomic DNA No translation available.
AL451130 Genomic DNA No translation available.
AL583805 Genomic DNA No translation available.
AL590397 Genomic DNA No translation available.
AL591133 Genomic DNA No translation available.
AL596451 Genomic DNA No translation available.
AL669908 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000463477; ENSP00000417661; ENSG00000153707
ENST00000634307; ENSP00000489546; ENSG00000282932
UCSCiuc003zkt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC245202 Genomic DNA No translation available.
AL137125 Genomic DNA No translation available.
AL353638 Genomic DNA No translation available.
AL356584 Genomic DNA No translation available.
AL445926 Genomic DNA No translation available.
AL451130 Genomic DNA No translation available.
AL583805 Genomic DNA No translation available.
AL590397 Genomic DNA No translation available.
AL591133 Genomic DNA No translation available.
AL596451 Genomic DNA No translation available.
AL669908 Genomic DNA No translation available.

3D structure databases

SMRiC9J8S8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9J8S8
PRIDEiC9J8S8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000463477; ENSP00000417661; ENSG00000153707
ENST00000634307; ENSP00000489546; ENSG00000282932
UCSCiuc003zkt.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000153707.15
HGNCiHGNC:9668 PTPRD
OpenTargetsiENSG00000153707
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4228 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00760000118900
HOGENOMiHOG000286012

Miscellaneous databases

ChiTaRSiPTPRD human

Gene expression databases

BgeeiENSG00000153707 Expressed in 196 organ(s), highest expression level in forebrain
ExpressionAtlasiC9J8S8 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF07679 I-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiC9J8S8_HUMAN
AccessioniPrimary (citable) accession number: C9J8S8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 10, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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