UniProtKB - C9J8C7 (C9J8C7_HUMAN)
Protein
Submitted name:
Long-chain-fatty-acid--CoA ligase 6
Gene
ACSL6
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Long-chain-fatty-acid--CoA ligase 6Imported |
Gene namesi | Name:ACSL6Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16496, ACSL6 |
VEuPathDBi | HostDB:ENSG00000164398.12 |
PTM / Processingi
Proteomic databases
MaxQBi | C9J8C7 |
PeptideAtlasi | C9J8C7 |
PRIDEi | C9J8C7 |
ProteomicsDBi | 9022 |
Expressioni
Gene expression databases
Bgeei | ENSG00000164398, Expressed in corpus callosum and 167 other tissues |
ExpressionAtlasi | C9J8C7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 105 – 552 | AMP-bindingInterPro annotationAdd BLAST | 448 | |
Domaini | 562 – 602 | AMP-binding_CInterPro annotationAdd BLAST | 41 |
Sequence similaritiesi
Belongs to the ATP-dependent AMP-binding enzyme family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000162308 |
HOGENOMi | CLU_052411_1_1_1 |
Family and domain databases
Gene3Di | 3.40.50.12780, 2 hits |
InterProi | View protein in InterPro IPR025110, AMP-bd_C IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit PF13193, AMP-binding_C, 1 hit |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All
C9J8C7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLTFFLVSGG SLWLFVEFVL SLLEKMQTQE ILRILRLPEL GDLGQFFRSL
60 70 80 90 100
SATTLDSGGA RRSVIGSGPQ LLTHYYDDAR TMYQVFRRGL SISGNGPCLG
110 120 130 140 150
FRKPKQPYQW LSYQEVADRA EFLGSGLLQH NCKACTDQFI GVFAQNRPEW
160 170 180 190 200
IIVELACYTY SMVVVPLYDT LGPGAIRYII NTADISTVIV DKPQKAVLLL
210 220 230 240 250
EHVERKETPG LKLIILMDPF EEALKERGQK CGVVIKSMQA VEDCGQENHQ
260 270 280 290 300
APVPPQPDDL SIVCFTSGTT GNPKGAMLTH GNVVADFSGF LKVTEKVIFP
310 320 330 340 350
RQDDVLISFL PLAHMFERVI QSVVYCHGGR VGFFQGDIRL LSDDMKALCP
360 370 380 390 400
TIFPVVPRLL NRMYDKIFSQ ANTPLKRWLL EFAAKRKQAE VRSGIIRNDS
410 420 430 440 450
IWDELFFNKI QASLGGCVRM IVTGAAPASP TVLGFLRAAL GCQVYEGYGQ
460 470 480 490 500
TECTAGCTFT TPGDWTSGHV GAPLPCNHIK LVDVEELNYW ACKGEGEICV
510 520 530 540 550
RGPNVFKGYL KDPDRTKEAL DSDGWLHTGD IGKWLPAGTL KIIDRKKHIF
560 570 580 590 600
KLAQGEYVAP EKIENIYIRS QPVAQIYVHG DSLKAFLVGI VVPDPEVMPS
610 620 630 640 650
WAQKRGIEGT YADLCTNKDL KKAILEDMVR LGKESGLHSF EQVKAIHIHS
660 670 680
DMFSVQNGLL TPTLKAKRPE LREYFKKQIE ELYSISM
Computationally mapped potential isoform sequencesi
There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UKU0 | ACSL6_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 ACS2, FACL6, KIAA0837, LACS5 | 697 | Annotation score: | ||
A0A494C0B6 | A0A494C0B6_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 720 | Annotation score: | ||
A0A499FJL5 | A0A499FJL5_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 710 | Annotation score: | ||
C9J3Z0 | C9J3Z0_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 213 | Annotation score: | ||
C9JK59 | C9JK59_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 152 | Annotation score: | ||
C9J4I1 | C9J4I1_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 144 | Annotation score: | ||
C9JPA5 | C9JPA5_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 134 | Annotation score: | ||
A0A494C005 | A0A494C005_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 332 | Annotation score: | ||
A0A494C0A5 | A0A494C0A5_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 338 | Annotation score: | ||
A0A494C0V0 | A0A494C0V0_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 49 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC034228 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000434099; ENSP00000397507; ENSG00000164398 |
UCSCi | uc063gsx.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC034228 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | C9J8C7 |
PeptideAtlasi | C9J8C7 |
PRIDEi | C9J8C7 |
ProteomicsDBi | 9022 |
Protocols and materials databases
Antibodypediai | 25915, 187 antibodies |
Genome annotation databases
Ensembli | ENST00000434099; ENSP00000397507; ENSG00000164398 |
UCSCi | uc063gsx.1, human |
Organism-specific databases
HGNCi | HGNC:16496, ACSL6 |
OpenTargetsi | ENSG00000164398 |
VEuPathDBi | HostDB:ENSG00000164398.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000162308 |
HOGENOMi | CLU_052411_1_1_1 |
Miscellaneous databases
ChiTaRSi | ACSL6, human |
Gene expression databases
Bgeei | ENSG00000164398, Expressed in corpus callosum and 167 other tissues |
ExpressionAtlasi | C9J8C7, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.12780, 2 hits |
InterProi | View protein in InterPro IPR025110, AMP-bd_C IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit PF13193, AMP-binding_C, 1 hit |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9J8C7_HUMAN | |
Accessioni | C9J8C7Primary (citable) accession number: C9J8C7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | June 5, 2019 | |
Last modified: | February 10, 2021 | |
This is version 64 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |