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Protein
Submitted name:

Integrator complex subunit 6

Gene

INTS6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Integrator complex subunit 6Imported
Gene namesi
Name:INTS6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000102786.14
HGNCiHGNC:14879 INTS6

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000102786

PTM / Processingi

Proteomic databases

MaxQBiC9J885
PeptideAtlasiC9J885
PRIDEiC9J885

Expressioni

Gene expression databases

BgeeiENSG00000102786 Expressed in 217 organ(s), highest expression level in testis
ExpressionAtlasiC9J885 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9J885
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 118VWFAInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili50 – 70Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3768 Eukaryota
ENOG410XRER LUCA
GeneTreeiENSGT00390000016655
HOGENOMiHOG000070213

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF13519 VWA_2, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

C9J885-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNQRSHLGTT YLDTAKGAVE TFMKLRARDP ASRGDRYMLV TFEEPPYAIK
60 70 80 90 100
AGWKENHATF MNELKNLQAE GLTTLGQSLR TAFDLLNLNR LVTGIDNYGQ
110 120
GRNPFFLEPA IIITITDGSK LTTTSG
Length:126
Mass (Da):14,027
Last modified:November 3, 2009 - v1
Checksum:iE5931140C5B021B4
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UL03INT6_HUMAN
Integrator complex subunit 6
INTS6 DBI1, DDX26, DDX26A
887Annotation score:
B3KQH5B3KQH5_HUMAN
Integrator complex subunit 6, isofo...
INTS6 hCG_29123
709Annotation score:
G5E9X1G5E9X1_HUMAN
Integrator complex subunit 6, isofo...
INTS6 hCG_29123
571Annotation score:
C9K0V7C9K0V7_HUMAN
Integrator complex subunit 6
INTS6
130Annotation score:
F8WAV7F8WAV7_HUMAN
Integrator complex subunit 6
INTS6
151Annotation score:
C9JAV7C9JAV7_HUMAN
Integrator complex subunit 6
INTS6
154Annotation score:
C9JVX2C9JVX2_HUMAN
Integrator complex subunit 6
INTS6
131Annotation score:
C9JXP6C9JXP6_HUMAN
Integrator complex subunit 6
INTS6
89Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei126Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137780 Genomic DNA No translation available.
AL354820 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000483288; ENSP00000417707; ENSG00000102786
UCSCiuc058xea.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137780 Genomic DNA No translation available.
AL354820 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9J885
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9J885
PeptideAtlasiC9J885
PRIDEiC9J885

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000483288; ENSP00000417707; ENSG00000102786
UCSCiuc058xea.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000102786.14
HGNCiHGNC:14879 INTS6
OpenTargetsiENSG00000102786
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3768 Eukaryota
ENOG410XRER LUCA
GeneTreeiENSGT00390000016655
HOGENOMiHOG000070213

Miscellaneous databases

ChiTaRSiINTS6 human

Gene expression databases

BgeeiENSG00000102786 Expressed in 217 organ(s), highest expression level in testis
ExpressionAtlasiC9J885 baseline and differential

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF13519 VWA_2, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9J885_HUMAN
AccessioniPrimary (citable) accession number: C9J885
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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