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Protein
Submitted name:

DNA repair protein RAD51 homolog 2

Gene

RAD51B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA repair protein RAD51 homolog 2Imported
Gene namesi
Name:RAD51BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000182185.18
HGNCiHGNC:9822 RAD51B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182185

PTM / Processingi

Proteomic databases

PeptideAtlasiC9J5S9

Expressioni

Gene expression databases

BgeeiENSG00000182185 Expressed in 149 organ(s), highest expression level in corpus callosum
ExpressionAtlasiC9J5S9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9J5S9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 133RECA_2InterPro annotationAdd BLAST55

Phylogenomic databases

eggNOGiKOG1433 Eukaryota
COG0468 LUCA
GeneTreeiENSGT00860000133731
HOGENOMiHOG000154062

Family and domain databases

InterProiView protein in InterPro
IPR013632 DNA_recomb/repair_Rad51_C
IPR027417 P-loop_NTPase
IPR030548 RAD51B
IPR020588 RecA_ATP-bd
PANTHERiPTHR22942:SF15 PTHR22942:SF15, 1 hit
PfamiView protein in Pfam
PF08423 Rad51, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50162 RECA_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

C9J5S9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSKKLKRVG LSQELCDRLS RHQILTCQDF LCLSPLELMK VTGLSYRGVH
60 70 80 90 100
ELLCMVSRAC APKMQTAYGI KAQRSADFSP AFLSTTLSAL DEALHGGVAC
110 120 130
GSLTEITGPP GCGKTQFCIM MSILATLPTN MGG
Length:133
Mass (Da):14,214
Last modified:November 3, 2009 - v1
Checksum:iFF328474FD3221EC
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15315RA51B_HUMAN
DNA repair protein RAD51 homolog 2
RAD51B RAD51L1, REC2
384Annotation score:
A0A0A0MS18A0A0A0MS18_HUMAN
DNA repair protein RAD51 homolog 2
RAD51B
279Annotation score:
C9JYJ0C9JYJ0_HUMAN
DNA repair protein RAD51 homolog 2
RAD51B
425Annotation score:
F8WAY6F8WAY6_HUMAN
DNA repair protein RAD51 homolog 2
RAD51B
108Annotation score:
G3V4W9G3V4W9_HUMAN
DNA repair protein RAD51 homolog 2
RAD51B
75Annotation score:
H0YJI5H0YJI5_HUMAN
DNA repair protein RAD51 homolog 2
RAD51B
35Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei133Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121595 Genomic DNA No translation available.
AL133370 Genomic DNA No translation available.
KC877523 Genomic DNA No translation available.
KF455917 Genomic DNA No translation available.
KF455919 Genomic DNA No translation available.
KF455920 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000485181; ENSP00000417948; ENSG00000182185
UCSCiuc059csb.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121595 Genomic DNA No translation available.
AL133370 Genomic DNA No translation available.
KC877523 Genomic DNA No translation available.
KF455917 Genomic DNA No translation available.
KF455919 Genomic DNA No translation available.
KF455920 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9J5S9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9J5S9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000485181; ENSP00000417948; ENSG00000182185
UCSCiuc059csb.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000182185.18
HGNCiHGNC:9822 RAD51B
OpenTargetsiENSG00000182185
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1433 Eukaryota
COG0468 LUCA
GeneTreeiENSGT00860000133731
HOGENOMiHOG000154062

Miscellaneous databases

ChiTaRSiRAD51B human

Gene expression databases

BgeeiENSG00000182185 Expressed in 149 organ(s), highest expression level in corpus callosum
ExpressionAtlasiC9J5S9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013632 DNA_recomb/repair_Rad51_C
IPR027417 P-loop_NTPase
IPR030548 RAD51B
IPR020588 RecA_ATP-bd
PANTHERiPTHR22942:SF15 PTHR22942:SF15, 1 hit
PfamiView protein in Pfam
PF08423 Rad51, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50162 RECA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9J5S9_HUMAN
AccessioniPrimary (citable) accession number: C9J5S9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 12, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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