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Protein
Submitted name:

Semaphorin-4C

Gene

SEMA4C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Semaphorin-4CImported
Gene namesi
Name:SEMA4CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000168758.10
HGNCiHGNC:10731 SEMA4C

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168758

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500841293321 – 139Sequence analysisAdd BLAST119

Proteomic databases

PeptideAtlasiC9J4M7
PRIDEiC9J4M7

Expressioni

Gene expression databases

BgeeiENSG00000168758 Expressed in 234 organ(s), highest expression level in trigeminal ganglion
ExpressionAtlasiC9J4M7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9J4M7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 139SemaInterPro annotationAdd BLAST110

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3611 Eukaryota
ENOG410XQZC LUCA
GeneTreeiENSGT00760000118854
HOGENOMiHOG000213692

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR001627 Semap_dom
IPR036352 Semap_dom_sf
IPR027231 Semaphorin
IPR015943 WD40/YVTN_repeat-like_dom_sf
PANTHERiPTHR11036 PTHR11036, 1 hit
PfamiView protein in Pfam
PF01403 Sema, 1 hit
SUPFAMiSSF101912 SSF101912, 1 hit
PROSITEiView protein in PROSITE
PS51004 SEMA, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

C9J4M7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPHWAVWLL AARLWGLGIG AEVWWNLVPR KTVSSGELAT VVRRFSQTGI
60 70 80 90 100
QDFLTLTLTE PTGLLYVGAR EALFAFSMEA LELQGAISWE APVEKKTECI
110 120 130
QKGKNNQTEC FNFIRFLQPY NASHLYVCGT YAFQPKCTY
Length:139
Mass (Da):15,709
Last modified:October 5, 2016 - v8
Checksum:iA1C32C8ADAA5A0E1
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9C0C4SEM4C_HUMAN
Semaphorin-4C
SEMA4C KIAA1739, SEMAI, UNQ5855/PRO34487
833Annotation score:
C9JV89C9JV89_HUMAN
Semaphorin-4C
SEMA4C
201Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei139Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092636 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000449330; ENSP00000391094; ENSG00000168758
UCSCiuc061lxv.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092636 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9J4M7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9J4M7
PRIDEiC9J4M7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000449330; ENSP00000391094; ENSG00000168758
UCSCiuc061lxv.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168758.10
HGNCiHGNC:10731 SEMA4C
OpenTargetsiENSG00000168758
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3611 Eukaryota
ENOG410XQZC LUCA
GeneTreeiENSGT00760000118854
HOGENOMiHOG000213692

Gene expression databases

BgeeiENSG00000168758 Expressed in 234 organ(s), highest expression level in trigeminal ganglion
ExpressionAtlasiC9J4M7 baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR001627 Semap_dom
IPR036352 Semap_dom_sf
IPR027231 Semaphorin
IPR015943 WD40/YVTN_repeat-like_dom_sf
PANTHERiPTHR11036 PTHR11036, 1 hit
PfamiView protein in Pfam
PF01403 Sema, 1 hit
SUPFAMiSSF101912 SSF101912, 1 hit
PROSITEiView protein in PROSITE
PS51004 SEMA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9J4M7_HUMAN
AccessioniPrimary (citable) accession number: C9J4M7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 68 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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