UniProtKB - C9J3Z0 (C9J3Z0_HUMAN)
Protein
Submitted name:
Long-chain-fatty-acid--CoA ligase 6
Gene
ACSL6
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Long-chain-fatty-acid--CoA ligase 6Imported |
Gene namesi | Name:ACSL6Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16496, ACSL6 |
VEuPathDBi | HostDB:ENSG00000164398.12 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 44 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000164398, Expressed in corpus callosum and 167 other tissues |
ExpressionAtlasi | C9J3Z0, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 115 – 204 | AMP-bindingInterPro annotationAdd BLAST | 90 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000162308 |
HOGENOMi | CLU_122204_0_0_1 |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All
C9J3Z0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQTQEILRIL RLPELGDLGQ FFRSLSATTL VSMGALAAIL AYWFTHRPKA
60 70 80 90 100
LQPPCNLLMQ SEEVEDSGGA RRSVIGSGPQ LLTHYYDDAR TMYQVFRRGL
110 120 130 140 150
SISGNGPCLG FRKPKQPYQW LSYQEVADRA EFLGSGLLQH NCKACTDQFI
160 170 180 190 200
GVFAQNRPEW IIVELACYTY SMVVVPLYDT LGPGAIRYII NTADISTVIV
210
DKPQKAVLLL EHV
Computationally mapped potential isoform sequencesi
There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UKU0 | ACSL6_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 ACS2, FACL6, KIAA0837, LACS5 | 697 | Annotation score: | ||
A0A494C0B6 | A0A494C0B6_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 720 | Annotation score: | ||
A0A499FJL5 | A0A499FJL5_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 710 | Annotation score: | ||
C9JK59 | C9JK59_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 152 | Annotation score: | ||
C9J4I1 | C9J4I1_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 144 | Annotation score: | ||
C9JPA5 | C9JPA5_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 134 | Annotation score: | ||
A0A494C005 | A0A494C005_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 332 | Annotation score: | ||
A0A494C0A5 | A0A494C0A5_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 338 | Annotation score: | ||
A0A494C0V0 | A0A494C0V0_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 49 | Annotation score: | ||
C9J8C7 | C9J8C7_HUMAN | Long-chain-fatty-acid--CoA ligase 6 | ACSL6 | 687 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 213 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC034228 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000430403; ENSP00000398423; ENSG00000164398 |
UCSCi | uc063gsz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC034228 Genomic DNA No translation available. |
3D structure databases
SMRi | C9J3Z0 |
ModBasei | Search... |
Proteomic databases
MaxQBi | C9J3Z0 |
PeptideAtlasi | C9J3Z0 |
ProteomicsDBi | 8410 |
Protocols and materials databases
Antibodypediai | 25915, 187 antibodies |
Genome annotation databases
Ensembli | ENST00000430403; ENSP00000398423; ENSG00000164398 |
UCSCi | uc063gsz.1, human |
Organism-specific databases
HGNCi | HGNC:16496, ACSL6 |
OpenTargetsi | ENSG00000164398 |
VEuPathDBi | HostDB:ENSG00000164398.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000162308 |
HOGENOMi | CLU_122204_0_0_1 |
Miscellaneous databases
ChiTaRSi | ACSL6, human |
Gene expression databases
Bgeei | ENSG00000164398, Expressed in corpus callosum and 167 other tissues |
ExpressionAtlasi | C9J3Z0, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9J3Z0_HUMAN | |
Accessioni | C9J3Z0Primary (citable) accession number: C9J3Z0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | February 10, 2021 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |