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Protein
Submitted name:

E3 ubiquitin-protein ligase KCMF1

Gene

KCMF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase KCMF1Imported
Gene namesi
Name:KCMF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000176407.17
HGNCiHGNC:20589 KCMF1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000176407

PTM / Processingi

Proteomic databases

MaxQBiC9J3I2
PeptideAtlasiC9J3I2
PRIDEiC9J3I2

Expressioni

Gene expression databases

BgeeiENSG00000176407 Expressed in 229 organ(s), highest expression level in sperm
ExpressionAtlasiC9J3I2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9J3I2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 55C2H2-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1280 Eukaryota
ENOG410XRX5 LUCA
GeneTreeiENSGT00510000047171
HOGENOMiHOG000007727

Family and domain databases

InterProiView protein in InterPro
IPR008598 Di19_Zn_binding_dom
IPR039858 KCMF1
IPR013087 Znf_C2H2_type
PANTHERiPTHR12268 PTHR12268, 1 hit
PfamiView protein in Pfam
PF05605 zf-Di19, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 1 hit
PROSITEiView protein in PROSITE
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

C9J3I2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQCILTRVDF DLYYGGEAFS VEQPQSFTCP YCGKMGYTET SLQEHVTSEH
60 70 80 90 100
AETSTEVICP ICAALPGGDP NHVTDDFAAH LTLEHRAPRD LDESSGVRHV
110 120 130 140
RRMFHPGRGL GGPRARRSNM HFTSSSTGGL SSSQSSYSPS NREAMDPIA
Length:149
Mass (Da):16,295
Last modified:November 3, 2009 - v1
Checksum:i49EEAB71955B3ED8
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9P0J7KCMF1_HUMAN
E3 ubiquitin-protein ligase KCMF1
KCMF1 FIGC, ZZZ1
381Annotation score:
C9JSW5C9JSW5_HUMAN
E3 ubiquitin-protein ligase KCMF1
KCMF1
47Annotation score:
A0A1D5RMQ3A0A1D5RMQ3_HUMAN
E3 ubiquitin-protein ligase KCMF1
KCMF1
10Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei149Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022210 Genomic DNA No translation available.
AC078974 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000453448; ENSP00000391340; ENSG00000176407
UCSCiuc061lev.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022210 Genomic DNA No translation available.
AC078974 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9J3I2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9J3I2
PeptideAtlasiC9J3I2
PRIDEiC9J3I2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000453448; ENSP00000391340; ENSG00000176407
UCSCiuc061lev.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000176407.17
HGNCiHGNC:20589 KCMF1
OpenTargetsiENSG00000176407
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1280 Eukaryota
ENOG410XRX5 LUCA
GeneTreeiENSGT00510000047171
HOGENOMiHOG000007727

Miscellaneous databases

ChiTaRSiKCMF1 human

Gene expression databases

BgeeiENSG00000176407 Expressed in 229 organ(s), highest expression level in sperm
ExpressionAtlasiC9J3I2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR008598 Di19_Zn_binding_dom
IPR039858 KCMF1
IPR013087 Znf_C2H2_type
PANTHERiPTHR12268 PTHR12268, 1 hit
PfamiView protein in Pfam
PF05605 zf-Di19, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 1 hit
PROSITEiView protein in PROSITE
PS50157 ZINC_FINGER_C2H2_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9J3I2_HUMAN
AccessioniPrimary (citable) accession number: C9J3I2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 7, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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