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Entry version 58 (12 Aug 2020)
Sequence version 1 (03 Nov 2009)
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Protein

Uncharacterized protein C4orf51

Gene

C4orf51

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
C9J302

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C4orf51
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C4orf51
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000237136.6

Human Gene Nomenclature Database

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HGNCi
HGNC:37264, C4orf51

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_C9J302

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
646603

Open Targets

More...
OpenTargetsi
ENSG00000237136

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA165663246

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
C9J302, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C4orf51

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003925381 – 202Uncharacterized protein C4orf51Add BLAST202

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
C9J302

PeptideAtlas

More...
PeptideAtlasi
C9J302

PRoteomics IDEntifications database

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PRIDEi
C9J302

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
8278

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
C9J302

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
C9J302

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000237136, Expressed in left testis and 86 other tissues

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000237136, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000391404

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
C9J302, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502T40P, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00520000060562

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_116990_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C9J302

Identification of Orthologs from Complete Genome Data

More...
OMAi
PEITRPF

Database of Orthologous Groups

More...
OrthoDBi
1622332at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
C9J302

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031708, DUF4722

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15849, DUF4722, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C9J302-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHYFYLTPQ ILLPFSPLTS QEFDLIRRKA GASWQDETRW SDSSVTTYTG
60 70 80 90 100
SYRKKQLDKS MCSQFSFRAG QHEPECKQMS LTNSSACHLL CWAGTQETTD
110 120 130 140 150
IKGLFPDITR PFKKSFDVKH GVAHQIWDFG DCFPTPPNYG KYCVRPKKPA
160 170 180 190 200
QEALINYSRR GKGVLKHLHG RCDSESKVCS SEDSEADRYS DYGWGGPSSP

FN
Length:202
Mass (Da):23,001
Last modified:November 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6C765B19DF740DEF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC093864 Genomic DNA No translation available.
AC107212 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

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CCDSi
CCDS47140.1

NCBI Reference Sequences

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RefSeqi
NP_001074000.1, NM_001080531.1
XP_006714352.1, XM_006714289.3
XP_011530498.1, XM_011532196.2
XP_011530499.1, XM_011532197.2
XP_016864036.1, XM_017008547.1
XP_016864037.1, XM_017008548.1
XP_016864038.1, XM_017008549.1
XP_016864039.1, XM_017008550.1
XP_016864040.1, XM_017008551.1
XP_016864041.1, XM_017008552.1
XP_016864042.1, XM_017008553.1
XP_016864043.1, XM_017008554.1
XP_016864044.1, XM_017008555.1
XP_016864045.1, XM_017008556.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000438731; ENSP00000391404; ENSG00000237136

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
646603

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:646603

UCSC genome browser

More...
UCSCi
uc003ikk.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093864 Genomic DNA No translation available.
AC107212 Genomic DNA No translation available.
CCDSiCCDS47140.1
RefSeqiNP_001074000.1, NM_001080531.1
XP_006714352.1, XM_006714289.3
XP_011530498.1, XM_011532196.2
XP_011530499.1, XM_011532197.2
XP_016864036.1, XM_017008547.1
XP_016864037.1, XM_017008548.1
XP_016864038.1, XM_017008549.1
XP_016864039.1, XM_017008550.1
XP_016864040.1, XM_017008551.1
XP_016864041.1, XM_017008552.1
XP_016864042.1, XM_017008553.1
XP_016864043.1, XM_017008554.1
XP_016864044.1, XM_017008555.1
XP_016864045.1, XM_017008556.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000391404

PTM databases

iPTMnetiC9J302
PhosphoSitePlusiC9J302

Polymorphism and mutation databases

BioMutaiC4orf51

Proteomic databases

PaxDbiC9J302
PeptideAtlasiC9J302
PRIDEiC9J302
ProteomicsDBi8278

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
62156, 46 antibodies

Genome annotation databases

EnsembliENST00000438731; ENSP00000391404; ENSG00000237136
GeneIDi646603
KEGGihsa:646603
UCSCiuc003ikk.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
646603
DisGeNETi646603
EuPathDBiHostDB:ENSG00000237136.6

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C4orf51
HGNCiHGNC:37264, C4orf51
HPAiENSG00000237136, Tissue enriched (testis)
neXtProtiNX_C9J302
OpenTargetsiENSG00000237136
PharmGKBiPA165663246

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502T40P, Eukaryota
GeneTreeiENSGT00520000060562
HOGENOMiCLU_116990_0_0_1
InParanoidiC9J302
OMAiPEITRPF
OrthoDBi1622332at2759
PhylomeDBiC9J302

Enzyme and pathway databases

PathwayCommonsiC9J302

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
646603, 12 hits in 835 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C4orf51, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
646603
PharosiC9J302, Tdark

Protein Ontology

More...
PROi
PR:C9J302
RNActiC9J302, protein

Gene expression databases

BgeeiENSG00000237136, Expressed in left testis and 86 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR031708, DUF4722
PfamiView protein in Pfam
PF15849, DUF4722, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCD051_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C9J302
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: November 3, 2009
Last modified: August 12, 2020
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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