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Protein
Submitted name:

Cleavage and polyadenylation-specificity factor subunit 7

Gene

CPSF7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Cleavage and polyadenylation-specificity factor subunit 7Imported
Gene namesi
Name:CPSF7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149532.15
HGNCiHGNC:30098 CPSF7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149532

PTM / Processingi

Proteomic databases

PeptideAtlasiC9J286
PRIDEiC9J286

Expressioni

Gene expression databases

BgeeiENSG00000149532 Expressed in 221 organ(s), highest expression level in pituitary gland
ExpressionAtlasiC9J286 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4849 Eukaryota
ENOG4111NBM LUCA
GeneTreeiENSGT00730000110905

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034772 CPSF6/7
IPR034770 CPSF7
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
PANTHERiPTHR23204 PTHR23204, 1 hit
PTHR23204:SF2 PTHR23204:SF2, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

C9J286-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEGVDLIDI YADEEFNQDP EFNNTDQIDL YDDVLTATSQ PSDDRSSSTE
60 70 80 90 100
PPPPVRQEPS PKPNNKTPAI LYTYSGLRNR RAAVYVGSFS WWTTDQQLIQ
110 120 130 140
VIRSIGVYDV VELKFAENRA NGQSKGYAEV VVASENSVHK LLE
Length:143
Mass (Da):16,058
Last modified:October 5, 2016 - v8
Checksum:iFADA1F73A2D5CB74
GO

Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8N684CPSF7_HUMAN
Cleavage and polyadenylation specif...
CPSF7
471Annotation score:
F5H6M0F5H6M0_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
219Annotation score:
F5H669F5H669_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
374Annotation score:
F5H047F5H047_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
288Annotation score:
J3QT54J3QT54_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
204Annotation score:
C9JM38C9JM38_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
138Annotation score:
C9J323C9J323_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
145Annotation score:
F5H6A8F5H6A8_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
101Annotation score:
F5H5B7F5H5B7_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
93Annotation score:
F5H1W4F5H1W4_HUMAN
Cleavage and polyadenylation-specif...
CPSF7
98Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei143Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003108 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000449811; ENSP00000392400; ENSG00000149532
UCSCiuc058ccf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003108 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9J286
PRIDEiC9J286

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000449811; ENSP00000392400; ENSG00000149532
UCSCiuc058ccf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000149532.15
HGNCiHGNC:30098 CPSF7
OpenTargetsiENSG00000149532
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4849 Eukaryota
ENOG4111NBM LUCA
GeneTreeiENSGT00730000110905

Miscellaneous databases

ChiTaRSiCPSF7 human

Gene expression databases

BgeeiENSG00000149532 Expressed in 221 organ(s), highest expression level in pituitary gland
ExpressionAtlasiC9J286 baseline and differential

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034772 CPSF6/7
IPR034770 CPSF7
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
PANTHERiPTHR23204 PTHR23204, 1 hit
PTHR23204:SF2 PTHR23204:SF2, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9J286_HUMAN
AccessioniPrimary (citable) accession number: C9J286
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 63 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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