GPR55

Functionⁱ

GO - Molecular functionⁱ

G-protein coupled receptor activity Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptorUniRule annotation, Receptor, Transducer

Molecular function

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: G-protein-coupled receptor 55Imported
Gene namesⁱ	Name:GPR55Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 2

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000135898.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:4511 GPR55

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	24 – 49	HelicalSequence analysisAdd BLAST	26
Transmembraneⁱ	61 – 79	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	99 – 117	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	138 – 161	HelicalSequence analysisAdd BLAST	24
Transmembraneⁱ	181 – 202	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	223 – 240	HelicalSequence analysisAdd BLAST	18

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000135898

OpenTargetsⁱ

ENSG00000135898

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	C9J1P7

PRIDEⁱ

C9J1P7

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000135898
ExpressionAtlasⁱ	C9J1P7 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9J1P7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	37 – 242	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		206

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IEJJ Eukaryota ENOG4111H9D LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149026
HOGENOMⁱ	HOG000013155

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR028334 GPR55
PANTHERⁱ	PTHR24232:SF56 PTHR24232:SF56, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9J1P7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSQQNTSGDC LFDGVNELMK TLQFAVHIPT FVLGLLLNLL AIHGFSTFLK 
        60         70         80         90        100
NRWPDYAATS IYMINLAVFD LLLVLSLPFK MVLSQVQSPF PSLCTLVECL 
       110        120        130        140        150
YFVSMYGSVF TICFISMDRF LAIRYPLLVS HLRSPRKIFG ICCTIWVLVW 
       160        170        180        190        200
TGSIPIYSFH GKVEKYMCFH NMSDDTWSAK VFFPLEVFGF LLPMGIMGFC 
       210        220        230        240 
CSRSIHILLG RRDHTQDWVQ QKACIYSIAA SLAVFVVSFL PV

Length:242

Mass (Da):27,522

Last modified:November 3, 2009 - v1

Checksum:ⁱBFA0D86340BFFB56

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	242	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC012507 Genomic DNA No translation available. AC092534 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC012507 Genomic DNA No translation available.
AC092534 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000438398; ENSP00000412768; ENSG00000135898
UCSC genome browser More...UCSCⁱ	uc061tkt.1 human

Protein	Similar proteins		Species	Score	Length
C9J1P7	G-protein coupled receptor 55		HUMAN		319
G protein-coupled receptor 55, isoform CRA_a		HUMAN		319

Protein	Similar proteins		Species	Score	Length
C9J1P7	G-protein coupled receptor 55		HUMAN		319
GPR55 isoform 1		PANTR		319
G protein-coupled receptor 55		MACMU		319
G protein-coupled receptor 55		MACFA		319
G protein-coupled receptor 55		MACNE		319
+17

Protein	Similar proteins		Species	Score	Length
C9J1P7	G-protein coupled receptor 55		HUMAN		319
G protein-coupled receptor 55		CERAT		319
G protein-coupled receptor 55		PONAB		319
G protein-coupled receptor 55		MANLE		319
G protein-coupled receptor 55		CHLSB		319
+53

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC012507 Genomic DNA No translation available. AC092534 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC012507 Genomic DNA No translation available.
AC092534 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	C9J1P7
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

Proteomic databases

PRIDEⁱ	C9J1P7

PRIDEⁱ

C9J1P7

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000438398; ENSP00000412768; ENSG00000135898
UCSC genome browser More...UCSCⁱ	uc061tkt.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000135898.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:4511 GPR55
Open Targets More...OpenTargetsⁱ	ENSG00000135898
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IEJJ Eukaryota ENOG4111H9D LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149026
HOGENOMⁱ	HOG000013155

Miscellaneous databases

ChiTaRSⁱ	GPR55 human

ChiTaRSⁱ

GPR55 human

Gene expression databases

Bgeeⁱ	ENSG00000135898
ExpressionAtlasⁱ	C9J1P7 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR028334 GPR55
PANTHERⁱ	PTHR24232:SF56 PTHR24232:SF56, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C9J1P7_HUMAN
Accessionⁱ	C9J1P7Primary (citable) accession number: C9J1P7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 3, 2009
	Last sequence update:	November 3, 2009
	Last modified:	June 20, 2018
	This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C9J1P7 (C9J1P7_HUMAN)

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G-protein-coupled receptor 55

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ