UniProtKB - C9J1P7 (C9J1P7_HUMAN)
Protein
Submitted name:
G-protein-coupled receptor 55
Gene
GPR55
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- G protein-coupled receptor activity Source: UniProtKB-KW
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotation, Receptor, Transducer |
Names & Taxonomyi
Protein namesi | Submitted name: G-protein-coupled receptor 55Imported |
Gene namesi | Name:GPR55Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000135898.9 |
HGNCi | HGNC:4511, GPR55 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 24 – 49 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 61 – 79 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 99 – 117 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 138 – 161 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 181 – 202 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 223 – 240 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000135898, Expressed in monocyte and 101 other tissues |
ExpressionAtlasi | C9J1P7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 37 – 242 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 206 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT01010000222244 |
HOGENOMi | CLU_009579_8_2_1 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR028334, GPR55 |
PANTHERi | PTHR24232:SF56, PTHR24232:SF56, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
C9J1P7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSQQNTSGDC LFDGVNELMK TLQFAVHIPT FVLGLLLNLL AIHGFSTFLK
60 70 80 90 100
NRWPDYAATS IYMINLAVFD LLLVLSLPFK MVLSQVQSPF PSLCTLVECL
110 120 130 140 150
YFVSMYGSVF TICFISMDRF LAIRYPLLVS HLRSPRKIFG ICCTIWVLVW
160 170 180 190 200
TGSIPIYSFH GKVEKYMCFH NMSDDTWSAK VFFPLEVFGF LLPMGIMGFC
210 220 230 240
CSRSIHILLG RRDHTQDWVQ QKACIYSIAA SLAVFVVSFL PV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ9Y2T6 | GPR55_HUMAN | G-protein coupled receptor 55 | GPR55 | 319 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 242 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012507 Genomic DNA No translation available. AC092534 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000438398; ENSP00000412768; ENSG00000135898 |
UCSCi | uc061tkt.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC012507 Genomic DNA No translation available. AC092534 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
GPCRDBi | Search... |
Proteomic databases
ProteomicsDBi | 8110 |
Protocols and materials databases
Antibodypediai | 20197, 173 antibodies |
Genome annotation databases
Ensembli | ENST00000438398; ENSP00000412768; ENSG00000135898 |
UCSCi | uc061tkt.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000135898.9 |
HGNCi | HGNC:4511, GPR55 |
OpenTargetsi | ENSG00000135898 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT01010000222244 |
HOGENOMi | CLU_009579_8_2_1 |
Miscellaneous databases
ChiTaRSi | GPR55, human |
Gene expression databases
Bgeei | ENSG00000135898, Expressed in monocyte and 101 other tissues |
ExpressionAtlasi | C9J1P7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR028334, GPR55 |
PANTHERi | PTHR24232:SF56, PTHR24232:SF56, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C9J1P7_HUMAN | |
Accessioni | C9J1P7Primary (citable) accession number: C9J1P7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | December 2, 2020 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |