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Protein
Submitted name:

Otogelin

Gene

OTOG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
OtogelinImported
Gene namesi
Name:OTOGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000188162.10
HGNCiHGNC:8516 OTOG

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188162

PTM / Processingi

Proteomic databases

PeptideAtlasiC9IZ84

Expressioni

Gene expression databases

BgeeiENSG00000188162 Expressed in 23 organ(s), highest expression level in pituitary gland
ExpressionAtlasiC9IZ84 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9IZ84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 66EGF-likeInterPro annotationAdd BLAST38

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IR87 Eukaryota
ENOG410Y3IZ LUCA
GeneTreeiENSGT00760000118896

Family and domain databases

InterProiView protein in InterPro
IPR000742 EGF-like_dom
IPR030105 Otogelin
PANTHERiPTHR11339:SF228 PTHR11339:SF228, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

C9IZ84-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
AMGDKATVVG GQAEAPDSVA MSSWERRLHR AKCAPSYLFS CFNGGECVHP
60 70 80 90
AFCDCRRFNA TGPRCQMVYN AGPERDSICR AWGQHHVETF DGLY
Length:94
Mass (Da):10,388
Last modified:May 27, 2015 - v2
Checksum:iA81FA68B2EFBFA36
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6ZRI0OTOG_HUMAN
Otogelin
OTOG OTGN
2,925Annotation score:
H9KVB3H9KVB3_HUMAN
Otogelin
OTOG
2,913Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei94Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124799 Genomic DNA No translation available.
KC877393 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000428619; ENSP00000399057; ENSG00000188162
UCSCiuc057znt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124799 Genomic DNA No translation available.
KC877393 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9IZ84
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9IZ84

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000428619; ENSP00000399057; ENSG00000188162
UCSCiuc057znt.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000188162.10
HGNCiHGNC:8516 OTOG
OpenTargetsiENSG00000188162
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IR87 Eukaryota
ENOG410Y3IZ LUCA
GeneTreeiENSGT00760000118896

Miscellaneous databases

ChiTaRSiOTOG human

Gene expression databases

BgeeiENSG00000188162 Expressed in 23 organ(s), highest expression level in pituitary gland
ExpressionAtlasiC9IZ84 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000742 EGF-like_dom
IPR030105 Otogelin
PANTHERiPTHR11339:SF228 PTHR11339:SF228, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9IZ84_HUMAN
AccessioniPrimary (citable) accession number: C9IZ84
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: May 27, 2015
Last modified: September 12, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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