Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein lifeguard 3

Gene

TMBIM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein lifeguard 3Imported
Gene namesi
Name:TMBIM1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000135926.12
HGNCiHGNC:23410 TMBIM1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei102 – 123HelicalUniRule annotationAdd BLAST22
Transmembranei129 – 149HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135926

PTM / Processingi

Proteomic databases

PeptideAtlasiC9IZ27
PRIDEiC9IZ27

Expressioni

Gene expression databases

BgeeiENSG00000135926 Expressed in 229 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiC9IZ27 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9IZ27
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BI1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2322 Eukaryota
COG0670 LUCA
GeneTreeiENSGT00500000044791
HOGENOMiHOG000070110

Family and domain databases

InterProiView protein in InterPro
IPR006214 Bax_inhibitor_1-related
PANTHERiPTHR23291 PTHR23291, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

C9IZ27-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNPSAPPPY EDRNPLYPGP PPPGGYGQPS VLPGGYPAYP GYPQPGYGHP
60 70 80 90 100
AGYPQPMPPT HPMPMNYGPG HGYDGEERAV SDSFGPGEWD DRKVRHTFIR
110 120 130 140 150
KVYSIISVQL LITVAIIAIF TFVEPVSAFV RRNVAVYYVS YAVFVVTYLI
Length:150
Mass (Da):16,473
Last modified:October 5, 2016 - v8
Checksum:i4EF213968A8C1C04
GO

Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q969X1LFG3_HUMAN
Protein lifeguard 3
TMBIM1 LFG3, RECS1, PP1201, PSEC0158
311Annotation score:
C9JW19C9JW19_HUMAN
Protein lifeguard 3
TMBIM1
167Annotation score:
C9JWV9C9JWV9_HUMAN
Protein lifeguard 3
TMBIM1
171Annotation score:
B3KSM0B3KSM0_HUMAN
Protein lifeguard 3
TMBIM1
137Annotation score:
F8WDY4F8WDY4_HUMAN
Protein lifeguard 3
TMBIM1
140Annotation score:
C9JEN3C9JEN3_HUMAN
Protein lifeguard 3
TMBIM1
106Annotation score:
C9IYT2C9IYT2_HUMAN
Protein lifeguard 3
TMBIM1
107Annotation score:
C9JAP5C9JAP5_HUMAN
Protein lifeguard 3
TMBIM1
91Annotation score:
B4DUD2B4DUD2_HUMAN
Protein lifeguard 3
TMBIM1
215Annotation score:
C9JN47C9JN47_HUMAN
Protein lifeguard 3
TMBIM1
73Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei150Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021016 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000418569; ENSP00000406744; ENSG00000135926
UCSCiuc061sjr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021016 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliC9IZ27
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9IZ27
PRIDEiC9IZ27

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000418569; ENSP00000406744; ENSG00000135926
UCSCiuc061sjr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000135926.12
HGNCiHGNC:23410 TMBIM1
OpenTargetsiENSG00000135926
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2322 Eukaryota
COG0670 LUCA
GeneTreeiENSGT00500000044791
HOGENOMiHOG000070110

Gene expression databases

BgeeiENSG00000135926 Expressed in 229 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiC9IZ27 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR006214 Bax_inhibitor_1-related
PANTHERiPTHR23291 PTHR23291, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC9IZ27_HUMAN
AccessioniPrimary (citable) accession number: C9IZ27
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 59 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again