Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei54NucleophileUniRule annotation1
Binding sitei116SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processtRNA processingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Elen_1051Imported
OrganismiEggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255) (Eubacterium lentum)Imported
Taxonomic identifieri479437 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCoriobacteriiaEggerthellalesEggerthellaceaeEggerthella
Proteomesi
  • UP000001377 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi479437.Elen_1051

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 110PseudoU_synth_1InterPro annotationAdd BLAST99
Domaini150 – 255PseudoU_synth_1InterPro annotationAdd BLAST106

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

C8WPD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDHTLALTL SYNGAPFSGF ARQPGQTTVQ GDLEDALRML FRRDVETTCA
60 70 80 90 100
GRTDAGVHAL GQVVSFDVDD RDIAGRSLPS LRRSLNALTH DAITVREVEP
110 120 130 140 150
KKLGFSARFD AQAREYHYHL CVDSTCPIFM KDFSWFVPGG LDITAMEAGA
160 170 180 190 200
QYLLGEHDFK SFCMAASAEG KPTHRNVREI SFHPETVMGE NLMSIKVVGN
210 220 230 240 250
AFLHSMVRTI VGTLVMVGKG QRDADWVGEV LEACDRRVAG ENAPAQGLVF

WRVIY
Length:255
Mass (Da):28,197
Last modified:November 3, 2009 - v1
Checksum:i2DCFAC9C479EA723
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001726 Genomic DNA Translation: ACV55022.1

Genome annotation databases

EnsemblBacteriaiACV55022; ACV55022; Elen_1051
KEGGiele:Elen_1051

Similar proteinsi

Entry informationi

Entry nameiC8WPD4_EGGLE
AccessioniPrimary (citable) accession number: C8WPD4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: July 18, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health