UniProtKB - C8VGY8 (C8VGY8_EMENI)
Protein
Submitted name:
Hypothetical D-isomer specific 2-hydroxyacid dehydrogenase (Eurofung)
Gene
ANIA_10668
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Functioni
GO - Molecular functioni
- glyoxylate reductase (NADP) activity Source: GO_Central
- hydroxypyruvate reductase activity Source: GO_Central
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: GO_Central
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Hypothetical D-isomer specific 2-hydroxyacid dehydrogenase (Eurofung)Imported |
Gene namesi | ORF Names:ANIA_10668Imported |
Organismi | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)Imported |
Taxonomic identifieri | 227321 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Nidulantes › |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 51 – 322 | 2-Hacid_dhInterPro annotationAdd BLAST | 272 | |
Domaini | 122 – 300 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 179 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0068, Eukaryota |
HOGENOMi | CLU_019796_1_3_1 |
InParanoidi | C8VGY8 |
OMAi | IICLCAN |
OrthoDBi | 911009at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR029752, D-isomer_DH_CS1 IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065, D_2_HYDROXYACID_DH_1, 1 hit PS00670, D_2_HYDROXYACID_DH_2, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
C8VGY8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIPRIMESHE KTVATQVLTE KRTVYMIDSL HPDAVEHAKM LWNVVLPGDK
60 70 80 90 100
KLNNWREHAT AVLVRGSYVT ADDIARAPNL IAIGKHGVGI DKIDQAACAK
110 120 130 140 150
RGIKILNTPG ANSRDVAELV VTLALTVARS IRSITTRQMT APVPKETCKG
160 170 180 190 200
LTLRRRTVGI IGMGNIGRTV AEIFHGGFDT KLVAYDAYTP DDAWPHLPHH
210 220 230 240 250
RAQSVQEVLE TADVLTLHVP LTDETHNLIS YEQLRQMKPD AILINAARGG
260 270 280 290 300
IVNERDLVRV LSEGHLWGAG LDCHEQEPPS VERYGKLWEN LNVVSTPHIG
310 320
AATNTAQRAS SMAAVENLYN YLCSIDAK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BN001305 Genomic DNA Translation: CBF82156.1 |
Genome annotation databases
EnsemblFungii | CBF82156; CBF82156; ANIA_10668 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BN001305 Genomic DNA Translation: CBF82156.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 162425.CADANIAP00003807 |
Genome annotation databases
EnsemblFungii | CBF82156; CBF82156; ANIA_10668 |
Phylogenomic databases
eggNOGi | KOG0068, Eukaryota |
HOGENOMi | CLU_019796_1_3_1 |
InParanoidi | C8VGY8 |
OMAi | IICLCAN |
OrthoDBi | 911009at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR029752, D-isomer_DH_CS1 IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065, D_2_HYDROXYACID_DH_1, 1 hit PS00670, D_2_HYDROXYACID_DH_2, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C8VGY8_EMENI | |
Accessioni | C8VGY8Primary (citable) accession number: C8VGY8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 3, 2009 |
Last sequence update: | November 3, 2009 | |
Last modified: | December 2, 2020 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |