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Entry version 47 (08 May 2019)
Sequence version 1 (03 Nov 2009)
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Protein

Elongator complex protein 1

Gene

ANIA_10551

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulationUniRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Elongator complex protein 1UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ANIA_10551Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri227321 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000560 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
162425.CADANIAP00006043

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ELP1/IKA1 family.UniRule annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000188454

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C8V8S8

Identification of Orthologs from Complete Genome Data

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OMAi
CTQTELA

Database of Orthologous Groups

More...
OrthoDBi
180136at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006849 Elp1

The PANTHER Classification System

More...
PANTHERi
PTHR12747 PTHR12747, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04762 IKI3, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017233 IKAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C8V8S8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRNLKNVRLA EVQLQNGLPL TATAWDTASD AVICTFGPTP TNPVIELRRK
60 70 80 90 100
RADVYFSDAV SPDVFDTIAS WDAPCPLPHL DCDHVLSLHY FADTLTACLV
110 120 130 140 150
LEGGDIIVVR EEPLPGEDKI EIVGSVDVGI TAAAWSPDEE LLALTTSAHT
160 170 180 190 200
FLYMTREFEN VAEITFTPDD LKASQHVSVG WGKRETQFQG KRAKAMRDPT
210 220 230 240 250
VPEKVDEGKL SGNDDGRTTI TWRGDGAFVA VNSIVEGIRR AIRVYSREGT
260 270 280 290 300
LDSVSEPVDG LEGALSWRPY GNLIAGIQRL DDRIDVVFFE RNGLRHGQFT
310 320 330 340 350
LRLTEEERST WASNIHLSWN VDSTVLAVQF KDRIQFWTSG NYHYYLKQEI
360 370 380 390 400
PVIVSSEGPF AYKWHHEKAL RFVAGASDLI QTNGSAESIL DGEFVFKVFH
410 420 430 440 450
GSTTPPNDVG AVAVIDGKTL KLTPLKLSGV PPPMAHNELP LDANAIDVAF
460 470 480 490 500
SKSGTRIAVL MNDHFSVYLW SLKSRPVPVP ILESSYPLSG EIGSRPRQIT
510 520 530 540 550
FLNDNEVYIL RSRGPNNTCI ERTTLETRET KVVYEAADSE HLLTMFSSLG
560 570 580 590 600
HEALWFSHVP RPGQSIAYST ITMPSSNESQ VTPWAQSPVA DTYWAKSAQI
610 620 630 640 650
SDDEVGLVLI SLSRTGGLYA NKKLLAKNCT SFLLTSSHVI FTTSLHLLKF
660 670 680 690 700
VHLRRAEDME APPDTPETDE RCRSIERGSR LVTVMPSAFA VVLQAPRGNI
710 720 730 740 750
ETIYPRALVL AGIRSFIDKK DYRSAFLTCR SQMVDMNLIH DYAPEQFMES
760 770 780 790 800
ITLFVDQVKR VDFVDEFLSR LKEEDVSQTL YKDTLKALDM EVAAETGFTM
810 820 830 840 850
TGKKGSKVNR ICDGFLTALE KRSDTNLHNL ITAHVCKLPP DLESGLQLVA
860 870 880 890 900
RLREESPEQA EDAVEHMCFL TDANRLYDTA LGLYDLELTL LVAQQAQRDP
910 920 930 940 950
REYLPFLRKL QQLPDLRRFF EIDNYLGRWQ KALGHLHGLH AHDELREYVV
960 970 980 990 1000
KHVLYKDAID IYKYEPEQLR DITHLYADHL YQESQYKDAG IAYESLSMYT
1010 1020 1030 1040 1050
DAYKCYQLAH LWRESLYTAM LVPLSQDELT THATDLATTL VEENKDYLAA
1060 1070 1080 1090 1100
SQIHAEHLHD IPTAARLLCR GARYSEATRL LTLHSVQSLI PEIVDVALAD
1110 1120 1130 1140 1150
AMGSMTDLLA DFRSQLQAQV PRIAELRVRR IQDPLAYFGG DPTATDGAAG
1160 1170 1180 1190 1200
VDIPDNVSLA ATDASTLAGK SMFTRYTGKT SSGKTTSSRQ SSRNRRKEER
1210 1220 1230 1240 1250
KRARGKKGTV YEEEYLVNSV RRLIERVGTT VPEVENLVDS LLRRGMRERA
1260 1270 1280 1290 1300
AAIEKATRDV LKLCEESQEE VFIVQQKQQL EEGENGEQGG EAVNGPVDVP
1310 1320 1330
MPQGGQRVFW ESIVSTLGGG KGQEPPKIKE MKKSALLS
Length:1,338
Mass (Da):149,680
Last modified:November 3, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i201567EEB051FD26
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BN001303 Genomic DNA Translation: CBF77576.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
CBF77576; CBF77576; ANIA_10551

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001303 Genomic DNA Translation: CBF77576.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi162425.CADANIAP00006043

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCBF77576; CBF77576; ANIA_10551

Phylogenomic databases

HOGENOMiHOG000188454
InParanoidiC8V8S8
OMAiCTQTELA
OrthoDBi180136at2759

Family and domain databases

InterProiView protein in InterPro
IPR006849 Elp1
PANTHERiPTHR12747 PTHR12747, 1 hit
PfamiView protein in Pfam
PF04762 IKI3, 1 hit
PIRSFiPIRSF017233 IKAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC8V8S8_EMENI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C8V8S8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 8, 2019
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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