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UniProtKB - C8C1R6 (C8C1R6_HORSE)

Entry version 27 (12 Aug 2020)
Sequence version 1 (13 Oct 2009)
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Protein
Submitted name:

Enamelin

Gene

ENAM

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
EnamelinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ENAMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 122DisorderedSequence analysisAdd BLAST122
Regioni167 – 248DisorderedSequence analysisAdd BLAST82
Regioni360 – 382DisorderedSequence analysisAdd BLAST23
Regioni581 – 613DisorderedSequence analysisAdd BLAST33
Regioni708 – 746DisorderedSequence analysisAdd BLAST39
Regioni817 – 842DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi7 – 25PolyampholyteSequence analysisAdd BLAST19
Compositional biasi27 – 86PolarSequence analysisAdd BLAST60
Compositional biasi171 – 191PolarSequence analysisAdd BLAST21
Compositional biasi215 – 236PolyampholyteSequence analysisAdd BLAST22
Compositional biasi360 – 377PolyampholyteSequence analysisAdd BLAST18
Compositional biasi592 – 613PolarSequence analysisAdd BLAST22

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_280412_0_0_1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR015673, Enamelin

The PANTHER Classification System

More...PANTHERi		PTHR16784, PTHR16784, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15362, Enamelin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

C8C1R6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
RPPYYSEEMF EDFEKPKEED PPKAESPATE PSSNSTVPEN NSTQPNAPNP 
        60         70         80         90        100
RGSQGGNDTS PTGNSGYGPN TVSNRTVQNG VILPPTVNIS GQGIPRRQIP 
       110        120        130        140        150
WRPSQPKIHE NYPNPNIRNF PARRQWRPTG TATGNRQNGP FYRNQVQRDP 
       160        170        180        190        200
QWNSFAWEGK RTVHPGNPIY RKSYTPTTRG NSPNNAGNPA NIRRKPQGPN 
       210        220        230        240        250
KPPVVTNVPL GPKHDTVDLN EKVQNPREKP PDQKEIVIPT RDPPGPWRNS 
       260        270        280        290        300
EDYGINKPNY KLPHSEGNIL VPNFNSVDQR ENSYYPRGDI IRAPNYDGQT 
       310        320        330        340        350
QSQNLPKGII LEPRRIPYES ETNQPELKHS TYQPVYPEET PSPAREHFPT 
       360        370        380        390        400
ERNTWNHQEI SPHFKEDPGR QEEHLPHPSL GSRGGVYYPD YYPYDPRENS 
       410        420        430        440        450
PYFRGNAWDE RNYSPNTMGR LKNPLYPVNT PDVKETVLYN EEDPTDPTGG 
       460        470        480        490        500
EAFPGQSRWG VEESSLKQGP TVRHYEGEQY TSNQQKEYLP YSLDNPSKPR 
       510        520        530        540        550
EDFPYGEFYP WNPDENFLSY DTAPTVLPPV ENKGYYTSDV IGQEENTPFP 
       560        570        580        590        600
SWNSWDHRIQ AQGQKEIRPY FNINFWDQPT NLHKAPANPP HQKENQPYSS 
       610        620        630        640        650
NSPAGLQKNP TWPEGENLNY GMQITRLNSP EGEHVAFPDS IPLSYPAGQK 
       660        670        680        690        700
EAHLFHLSQR SPCCVGGSIG PEDNPLALQD YTPSFGLLPG ENQDTSLLYM 
       710        720        730        740        750
EDSHTNHARD TISPTIIPPV EGNSSEKRLP GESQNPSPFG DDVSPLRRNI 
       760        770        780        790        800
PCSIKNQLGQ RGIMPIPEAS SLQPKNTPCL KSDLGGDGNN VLERIFEGNQ 
       810        820        830        840        850
LNERTVDLTP EQLVIDIPDE GPKPEGIQSE VQGNEGERQQ QRPPSILQLP 
       860        870        880        890        900
CFGSNLAKYH SSGAGTPSSI GRPGLFDGDP IMPTEIPNSL AGLATGAEFQ 
       910        920
SISVDPLNAD EHTSFDYLQI
Length:920
Mass (Da):103,188
Last modified:October 13, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7C9B56F8E181FE58
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei920Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
GQ354858 Genomic DNA Translation: ACU42222.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ354858 Genomic DNA Translation: ACU42222.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Phylogenomic databases

HOGENOMiCLU_280412_0_0_1

Family and domain databases

InterProiView protein in InterPro
IPR015673, Enamelin
PANTHERiPTHR16784, PTHR16784, 1 hit
PfamiView protein in Pfam
PF15362, Enamelin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC8C1R6_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C8C1R6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: August 12, 2020
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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