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Protein
Submitted name:

Cathepsin D (Lysosomal aspartyl protease)

Gene

ctsd

Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteaseUniRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.009

Names & Taxonomyi

Protein namesi
Submitted name:
Cathepsin D (Lysosomal aspartyl protease)Imported (EC:3.4.23.5Imported)
Gene namesi
Name:ctsdImported
OrganismiSchistosoma japonicum (Blood fluke)Imported
Taxonomic identifieri6182 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 240Peptidase A1InterPro annotationAdd BLAST175

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR012848 Aspartic_peptidase_N
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF07966 A1_Propeptide, 1 hit
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 1 hit
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Fragment.

C7TZL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHLLLLLHL VSSEVVRVPL YPLKSARRSL IEFETSLENV QKVWFSRFSN
60 70 80 90 100
VEPRPEYLKN YLDAQYYGDI TIGTPPQTFS VVFDTGSSNL WVPSKHCSYF
110 120 130 140 150
DIACLLHRKY DSSKSTTYVP NGTDFSIRYG TGSLSGFLST DSLQLGSLGV
160 170 180 190 200
KGQTFGEATK QPGLVFVMAK FDGILGMAYP SLAVGGVTPV FVNMIKQGVV
210 220 230 240
DSPVFSFYLS RNITNVLGGE LMIGGIDDKY YTGEINYVNL
Length:240
Mass (Da):26,576
Last modified:October 13, 2009 - v1
Checksum:i12AACF91B9A928F5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei240Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN330832 mRNA Translation: CAX83049.1

Similar proteinsi

Entry informationi

Entry nameiC7TZL5_SCHJA
AccessioniPrimary (citable) accession number: C7TZL5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: March 28, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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