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Entry version 56 (02 Dec 2020)
Sequence version 1 (13 Oct 2009)
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Protein
Submitted name:

Glycoside hydrolase family 43

Gene

Huta_2423

Organism
Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH43, Glycoside Hydrolase Family 43

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Glycoside hydrolase family 43Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Huta_2423Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHalorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri519442 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHaloarculaceaeHalorhabdus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002071 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
519442.Huta_2423

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini640 – 699DockerinInterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni581 – 652DisorderedSequence analysisAdd BLAST72

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi600 – 616AcidicSequence analysisAdd BLAST17
Compositional biasi638 – 652PolyampholyteSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 43 family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
arCOG03611, Archaea

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_394147_0_0_2

Database of Orthologous Groups

More...
OrthoDBi
32136at2157

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1330.10, 1 hit
2.115.10.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002105, Dockerin_1_rpt
IPR016134, Dockerin_dom
IPR036439, Dockerin_dom_sf
IPR018247, EF_Hand_1_Ca_BS
IPR006710, Glyco_hydro_43
IPR023296, Glyco_hydro_beta-prop_sf
IPR006311, TAT_signal

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00404, Dockerin_1, 1 hit
PF04616, Glyco_hydro_43, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF63446, SSF63446, 1 hit
SSF75005, SSF75005, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51766, DOCKERIN, 1 hit
PS00018, EF_HAND_1, 1 hit
PS51318, TAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C7NMF0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAGDDTHSL NRRHVLKSIG VGALGTTGIL GTSGSAIADN GGTHYSNPLY
60 70 80 90 100
GPDFADPTIH RAEDGTWWAY ASNMSYIEDS DERLIPILSS PDLVNWTYEG
110 120 130 140 150
EAFDSRPGWL YGSIWAPDVH YHDGQWVLFY ALWPRGDDDS QVPGIGVATS
160 170 180 190 200
ETPDGPFTDH GEILSNPDHP YPGNTIDPYF AYHNGTPYLF WANFAGINVV
210 220 230 240 250
ELTEDLQDYQ PGTFNQIAGS AYEGPAIFQR GDYWYVFGST GDCCDGFDST
260 270 280 290 300
YEVEVGRSEN LLGPYHDRDG TPMLERDEWN AGPTHLGDND RFVGPGHGDV
310 320 330 340 350
TVDDDGTYWF VYHAYDTEGP EFVDNGWPPA RQLFVDPIQW EDGWPIIGCD
360 370 380 390 400
GTPSSEMAVP GEGGYCSGGD DGTGDGGGVG DDVGDGTGDG YETWTDTDDP
410 420 430 440 450
YYATLVSDLT GYDLPSAGQF VNGTDESVVW DTYEIDGGNA DRLERSSLAV
460 470 480 490 500
GDEVPFSEAA RFSVTDPPEN PWGITLKSFG ERELERGQVL LGVAYMRTPG
510 520 530 540 550
EEASVTYKST ASTNTPDNYV TGAQPPLGAE WQRYYFPIEF GVSAAPGEWW
560 570 580 590 600
TEIWLGAAAQ TVDIGGLAVI DFAEGVRAHD LPVRAETGET AVGTDGDTDT
610 620 630 640 650
ETDTSGESEG EQDDSEAGGS EGTPAGGLPG GEGPSQDLDG DGLHEDVNGD
660 670 680 690
GTVDVSDVRS LLTNVNSEVV QKNADAYDFD GDGGVDVGDV LALYRRIYQ
Length:699
Mass (Da):75,179
Last modified:October 13, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1D5374F8B2A31DEF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001687 Genomic DNA Translation: ACV12589.1

NCBI Reference Sequences

More...
RefSeqi
WP_015790155.1, NC_013158.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACV12589; ACV12589; Huta_2423

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8384724

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hut:Huta_2423

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001687 Genomic DNA Translation: ACV12589.1
RefSeqiWP_015790155.1, NC_013158.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi519442.Huta_2423

Protein family/group databases

CAZyiGH43, Glycoside Hydrolase Family 43

Genome annotation databases

EnsemblBacteriaiACV12589; ACV12589; Huta_2423
GeneIDi8384724
KEGGihut:Huta_2423

Phylogenomic databases

eggNOGiarCOG03611, Archaea
HOGENOMiCLU_394147_0_0_2
OrthoDBi32136at2157

Family and domain databases

Gene3Di1.10.1330.10, 1 hit
2.115.10.20, 1 hit
InterProiView protein in InterPro
IPR002105, Dockerin_1_rpt
IPR016134, Dockerin_dom
IPR036439, Dockerin_dom_sf
IPR018247, EF_Hand_1_Ca_BS
IPR006710, Glyco_hydro_43
IPR023296, Glyco_hydro_beta-prop_sf
IPR006311, TAT_signal
PfamiView protein in Pfam
PF00404, Dockerin_1, 1 hit
PF04616, Glyco_hydro_43, 1 hit
SUPFAMiSSF63446, SSF63446, 1 hit
SSF75005, SSF75005, 1 hit
PROSITEiView protein in PROSITE
PS51766, DOCKERIN, 1 hit
PS00018, EF_HAND_1, 1 hit
PS51318, TAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC7NMF0_HALUD
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C7NMF0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: December 2, 2020
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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