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Entry version 74 (12 Aug 2020)
Sequence version 1 (13 Oct 2009)
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Protein
Submitted name:

HUN domain-containing protein

Gene

pqn-80

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
HUN domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pqn-80Imported
ORF Names:CELE_Y111B2A.14Imported, Y111B2A.14Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
Y111B2A.14a ; CE44134 ; WBGene00004161 ; pqn-80

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
C7IVS5

PeptideAtlas

More...
PeptideAtlasi
C7IVS5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004161, Expressed in multi-cellular organism and 4 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
C7IVS5, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
C7IVS5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini95 – 131HUNInterPro annotationAdd BLAST37

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni110 – 337DisorderedSequence analysisAdd BLAST228
Regioni517 – 536DisorderedSequence analysisAdd BLAST20
Regioni740 – 777DisorderedSequence analysisAdd BLAST38
Regioni913 – 958DisorderedSequence analysisAdd BLAST46
Regioni981 – 1061DisorderedSequence analysisAdd BLAST81
Regioni1104 – 1416DisorderedSequence analysisAdd BLAST313

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi134 – 149AcidicSequence analysisAdd BLAST16
Compositional biasi150 – 172PolyampholyteSequence analysisAdd BLAST23
Compositional biasi173 – 188PolarSequence analysisAdd BLAST16
Compositional biasi231 – 248PolyampholyteSequence analysisAdd BLAST18
Compositional biasi289 – 304PolarSequence analysisAdd BLAST16
Compositional biasi312 – 330PolarSequence analysisAdd BLAST19
Compositional biasi743 – 777PolarSequence analysisAdd BLAST35
Compositional biasi986 – 1027PolyampholyteSequence analysisAdd BLAST42
Compositional biasi1122 – 1161PolarSequence analysisAdd BLAST40
Compositional biasi1168 – 1222PolarSequence analysisAdd BLAST55
Compositional biasi1235 – 1407PolarSequence analysisAdd BLAST173

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014840, HRD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08729, HUN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All

C7IVS5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSLGSSKKK KKAEKSAKNE VIQIRISVAK PGSKKYTHVD WEELLKNNGK
60 70 80 90 100
ERDEDDLRRF YDEDTLFMAK KLGETRSKSG KKLRVNLDQL QHFNRKCGYD
110 120 130 140 150
MDDDFIDDTE IVDDEPTTSK KGGFYVGKGD VKDSNDEDEE EEEETDVEES
160 170 180 190 200
IQEVPKKVKI RKIKEKSGEK SSKSSDSSSS SSSDSEDAAG PPRMTGAPPS
210 220 230 240 250
IRMVSSSSSL KKLPAPRKPS PPPAVEPTRS VEIIEKPEKT EKPAEKRKTA
260 270 280 290 300
ATTSALEPAE KKKKPDSSSS SEEIILIDDN APAAKKQPES AQKGSTTVTM
310 320 330 340 350
SAKKICKQQE EIAKQKPSSS SVTPSKPAAP TASTPKKEEI GTLETFLKNI
360 370 380 390 400
FANLDAKGKL YQEKKLKTFD TETLKEITTF IDVMKHHKTE KVNMEPLIYS
410 420 430 440 450
LAKSFGMTTQ EVMKQVEQEI SSKKATTPKP STNAVLSTIS SQKSLEKNAA
460 470 480 490 500
DWKLTQTDLP TMGEKDIQML TTIVRSWKSK KEISNSMVTG WLKDVNQLKM
510 520 530 540 550
NADQARKKFF DIINTLPDSS EKNGGGGQQD ANDIPKHERS RKARMFLHQW
560 570 580 590 600
VYLSRKFLEL QLPKLKHHSP PVEGLAKKQV IAANAIKEGV RKQISLFENK
610 620 630 640 650
KDRLPGDPVY VFQFTEPVLT AVAPYLEDLV DYALAAKKIE LIVSGIDALH
660 670 680 690 700
QSTDGKITII QFYIEICRRL QKLSFLAVEE PMKSRLKEAN EQIMKHQVVQ
710 720 730 740 750
IPKYQLKWPD GQAEPSLKGL NRELYEFDKS ILSMVAAKPS APATPKASSS
760 770 780 790 800
TALRPSTSST PSQQQSTSTA KAMTSSSTSA EDAKRLLAMN QLVQVYAGKY
810 820 830 840 850
LLPTGNSTAD ICDPTICLMN DDILLIMVTA VYSCGIPLVN QMNMLKNVLC
860 870 880 890 900
QVGQTRMAQT LATQKTQNKQ CLTQNDYQLL FDYFGKFEKA LEQRKAKKEE
910 920 930 940 950
AERLKKLEEK LKKEKEKQAE KDRIEAKKFE ERMKKEQEKQ EEKERKEREK
960 970 980 990 1000
REEKERKERE IREIMERKKR EEDDRIAAKL QIAQQLENDR KMREAEESAR
1010 1020 1030 1040 1050
KETERRAKME TERKVAEARR AVERENQIKM MRAQQLQRRQ EEAPPPQQAP
1060 1070 1080 1090 1100
APHTQKIQVK NEPVDHSFDI LKEAEKDAHI IPTKSIKAEP LDVQKPLSAF
1110 1120 1130 1140 1150
EKLASLRGRT QSADMRRGGD STEMPNVTQQ YQAEQNHLAQ SSNNSQYNAP
1160 1170 1180 1190 1200
STSSQPQHFP TEPSIRQPPP QQSYNSNQML QNPRQQPQNQ IVQNFQSAPQ
1210 1220 1230 1240 1250
RHPHQNPQIA TSSSSGGVNQ FYNNGGAAPP VVEQQAANRR SSFTMSHSVQ
1260 1270 1280 1290 1300
QHQSPLQQQF PINSYQSPSH HNNSSSMSNS SLMQTPHSNS SMIARSPQFP
1310 1320 1330 1340 1350
SHTSPMSQRF HTPPSVGHQM VQSPLSQPNP SPLQHFNFSP HSSSFSSQRP
1360 1370 1380 1390 1400
QMPPQRQMSQ QNLMHQQQQP QNHTQHQYQH QTFSSQQQQL QQHQHQIRHQ
1410
MNTNYPPPPG YNHHGH
Length:1,416
Mass (Da):160,323
Last modified:October 13, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i22E52076E5F52600
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C7IVS6C7IVS6_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,446Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AX73A0A0K3AX73_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,449Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ARW1A0A0K3ARW1_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,419Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ARB9A0A0K3ARB9_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,063Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ARB4A0A0K3ARB4_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,226Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ARW5A0A0K3ARW5_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,066Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ARX0A0A0K3ARX0_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
560Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AU63A0A0K3AU63_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,256Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AU69A0A0K3AU69_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
1,036Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AU76A0A0K3AU76_CAEEL
HUN domain-containing protein
pqn-80 CELE_Y111B2A.14, Y111B2A.14
387Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CBB16282.1

NCBI Reference Sequences

More...
RefSeqi
NP_001255178.1, NM_001268249.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
Y111B2A.14a.1; Y111B2A.14a.1; WBGene00004161
Y111B2A.14a.2; Y111B2A.14a.2; WBGene00004161
Y111B2A.14a.3; Y111B2A.14a.3; WBGene00004161

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
176683

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CBB16282.1
RefSeqiNP_001255178.1, NM_001268249.1

3D structure databases

SMRiC7IVS5
ModBaseiSearch...

Proteomic databases

EPDiC7IVS5
PeptideAtlasiC7IVS5

Genome annotation databases

EnsemblMetazoaiY111B2A.14a.1; Y111B2A.14a.1; WBGene00004161
Y111B2A.14a.2; Y111B2A.14a.2; WBGene00004161
Y111B2A.14a.3; Y111B2A.14a.3; WBGene00004161
GeneIDi176683

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
176683
WormBaseiY111B2A.14a ; CE44134 ; WBGene00004161 ; pqn-80

Gene expression databases

BgeeiWBGene00004161, Expressed in multi-cellular organism and 4 other tissues
ExpressionAtlasiC7IVS5, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR014840, HRD
PfamiView protein in Pfam
PF08729, HUN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC7IVS5_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C7IVS5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 13, 2009
Last sequence update: October 13, 2009
Last modified: August 12, 2020
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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