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Protein

Conotoxin Lt11.1

Gene
N/A
Organism
Conus litteratus (Lettered cone)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionToxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Lt11.1
OrganismiConus litteratus (Lettered cone)
Taxonomic identifieri89445 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeConusElisaconus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23By similarityAdd BLAST23
PeptideiPRO_000039205124 – 50Conotoxin Lt11.1Add BLAST27
PropeptideiPRO_000039205253 – 63By similarityAdd BLAST11

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi24 ↔ 34By similarity
Disulfide bondi28 ↔ 39By similarity
Disulfide bondi33 ↔ 42By similarity
Disulfide bondi38 ↔ 47By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Family & Domainsi

Domaini

The cysteine framework is XI (C-C-CC-CC-C-C).

Sequence similaritiesi

Belongs to the conotoxin I2 superfamily.Curated

Keywords - Domaini

Signal

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C7DQC1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFRLTSVLL VIVLLNLVVL TNACHMDCSK MICCSGICCF YCGLPSCDDT
60
RRALLQRLLG HQR
Length:63
Mass (Da):7,094
Last modified:September 22, 2009 - v1
Checksum:iE48C88E82DDFAE0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ180869 mRNA Translation: ACU30731.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ180869 mRNA Translation: ACU30731.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiI2B1_CONLT
AccessioniPrimary (citable) accession number: C7DQC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 2, 2010
Last sequence update: September 22, 2009
Last modified: October 10, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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