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Protein

Pectinesterase

Gene

Amir_4198

Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Pectin + n H2O = n methanol + pectate.UniRule annotation

Pathwayi: pectin degradation

This protein is involved in step 1 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase (Amir_4198)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei349PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl esteraseUniRule annotation, Hydrolase

Enzyme and pathway databases

BioCyciAMIR446462:G1GEY-4263-MONOMER
UniPathwayiUPA00545; UER00823

Protein family/group databases

CAZyiCBM13 Carbohydrate-Binding Module Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
PectinesteraseUniRule annotation (EC:3.1.1.11UniRule annotation)
Gene namesi
Ordered Locus Names:Amir_4198Imported
OrganismiActinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)Imported
Taxonomic identifieri446462 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeActinosynnema
Proteomesi
  • UP000002213 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 44UniRule annotationAdd BLAST44
ChainiPRO_500512564445 – 487PectinesteraseUniRule annotationAdd BLAST443

Interactioni

Protein-protein interaction databases

STRINGi446462.Amir_4198

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 187Ricin B-type lectinInterPro annotationAdd BLAST140

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG41060YU Bacteria
COG4677 LUCA
OMAiVDRYERT
OrthoDBiPOG091H0DD6

Family and domain databases

CDDicd00161 RICIN, 1 hit
Gene3Di2.160.20.10, 1 hit
InterProiView protein in InterPro
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR033131 Pectinesterase_Asp_AS
IPR000070 Pectinesterase_cat
IPR035992 Ricin_B-like_lectins
IPR000772 Ricin_B_lectin
PfamiView protein in Pfam
PF01095 Pectinesterase, 1 hit
PF14200 RicinB_lectin_2, 1 hit
SMARTiView protein in SMART
SM00458 RICIN, 1 hit
SUPFAMiSSF50370 SSF50370, 1 hit
SSF51126 SSF51126, 1 hit
PROSITEiView protein in PROSITE
PS00503 PECTINESTERASE_2, 1 hit
PS50231 RICIN_B_LECTIN, 1 hit

Sequencei

Sequence statusi: Complete.

C6WHD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRESNVSVNK PGRRRGAPAT ALSAVAVVLM AGAAVVATTT AASAATPAAG
60 70 80 90 100
TTYTIAVKNS GKCLDVLDGN TANGALVAQW DCWNGAMQQW TLRDAGSGAF
110 120 130 140 150
TVVNVATGKC LDIPYGTTEY YVQAQQWSCS GDTMQRWRFT ASGSGTYQLV
160 170 180 190 200
NVASGLCLSN KDAGQGLGVP VVQEGCTANS NKQWLFTPAA SAERPTVAAD
210 220 230 240 250
GTGTYRKVQD AVNAAPSNSS ARTVITVKAG TYREVVTVPA DKPNITLRGL
260 270 280 290 300
GSGPSGTVIV YNNSAYTHGT SNSASFFARG AGFVAENLTI SNDLDESSVP
310 320 330 340 350
SGAQAVALQT NADRIVLRNV RLLGDQDTFL VNDATRAYVV DSYVEGTVDF
360 370 380 390 400
VFGGGTVVFH RTTVHEKRSG GGPITAASTG AGKKYGFLFY RSTITGAADD
410 420 430 440 450
VTQLGRPWRP DAQVLYREST LSATVRTSEP WTDMSDNSWR NARFLEYRNT
460 470 480
GSGAGSNSNR PQLSDSQAAE YTPQKYLAGS DGWNPIS
Length:487
Mass (Da):51,213
Last modified:September 22, 2009 - v1
Checksum:i883F2F9DE171B3C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001630 Genomic DNA Translation: ACU38053.1
RefSeqiWP_015802940.1, NC_013093.1

Genome annotation databases

EnsemblBacteriaiACU38053; ACU38053; Amir_4198
KEGGiami:Amir_4198

Similar proteinsi

Entry informationi

Entry nameiC6WHD4_ACTMD
AccessioniPrimary (citable) accession number: C6WHD4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: February 28, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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