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Protein

Alpha-galactosidase

Gene

Amir_3106

Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase
LigandLectinImported

Enzyme and pathway databases

BioCyciAMIR446462:G1GEY-3142-MONOMER

Protein family/group databases

CAZyiCBM13 Carbohydrate-Binding Module Family 13
GH27 Glycoside Hydrolase Family 27

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-galactosidaseUniRule annotation (EC:3.2.1.22UniRule annotation)
Alternative name(s):
MelibiaseUniRule annotation
Gene namesi
Ordered Locus Names:Amir_3106Imported
OrganismiActinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)Imported
Taxonomic identifieri446462 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeActinosynnema
Proteomesi
  • UP000002213 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 34Sequence analysisAdd BLAST34
ChainiPRO_500297259335 – 548Alpha-galactosidaseSequence analysisAdd BLAST514

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi446462.Amir_3106

Structurei

3D structure databases

ProteinModelPortaliC6W7Z9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini419 – 548Ricin B-type lectinInterPro annotationAdd BLAST130

Sequence similaritiesi

Belongs to the glycosyl hydrolase 27 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105EX0 Bacteria
ENOG410XPF1 LUCA
HOGENOMiHOG000161224
OMAiLAMTPTM
OrthoDBiPOG091H0DSB

Family and domain databases

CDDicd14792 GH27, 1 hit
cd00161 RICIN, 1 hit
Gene3Di2.60.40.1180, 1 hit
3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR002241 Glyco_hydro_27
IPR000111 Glyco_hydro_27/36_CS
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR035992 Ricin_B-like_lectins
IPR000772 Ricin_B_lectin
IPR006311 TAT_signal
PfamiView protein in Pfam
PF16499 Melibiase_2, 1 hit
PF00652 Ricin_B_lectin, 1 hit
PRINTSiPR00740 GLHYDRLASE27
SMARTiView protein in SMART
SM00458 RICIN, 1 hit
SUPFAMiSSF50370 SSF50370, 1 hit
SSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS00512 ALPHA_GALACTOSIDASE, 1 hit
PS50231 RICIN_B_LECTIN, 1 hit
PS51318 TAT, 1 hit

Sequencei

Sequence statusi: Complete.

C6W7Z9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPVRSRRRLT TLLLAALAAL TGVTAPTAHP PAQAAPGSPA LTPPLGWNSW
60 70 80 90 100
NSFGCGITEG QVRQAADAMA SSGMRDAGYR YVVVDDCWFD PQRDSAGNLR
110 120 130 140 150
NHPTKFPSGM KALGDYIHGK GLKFGIYQAP NEKTCAQGTG AHPGATGSKG
160 170 180 190 200
HEAQDARSFA SWGVDYLKYD WCSGAGTRDE QIARFTIMRD ALRATGRPIV
210 220 230 240 250
YSINPNSFHA ITGDKHDWGD VADLWRTTED LLDVWQNGNT NSYPMGVGNV
260 270 280 290 300
LDVTAPLAAQ TGPGNWNDPD MLVVGRPGLT LTESRAHFAL WALMAAPLMA
310 320 330 340 350
GNDIRTMSPE ISAVLRNPGL IAVNQDPLGA GGRRVRDDGA TEVFAKPLSD
360 370 380 390 400
GSVAVGLFNR GGGATTVATT AAQIGLSGTG FTLTDLWTGG TSTSSGAISA
410 420 430 440 450
TVPAHGVAAF RVTGGTPLAA TTSRLRGTGS GRCLDVDNAS TAAGATVLVW
460 470 480 490 500
DCHTAANQLW TTWAGGEVRV FGDKCLDAYE QGTVNGTRVV TWPCNGQDNQ
510 520 530 540
RWVVGSDGSV RNTRAGLCLD VDGAGTANGT RLVLWTCNGQ GNQRWSRT
Length:548
Mass (Da):57,602
Last modified:September 22, 2009 - v1
Checksum:i209FF523F7A50B32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001630 Genomic DNA Translation: ACU37020.1
RefSeqiWP_015801909.1, NC_013093.1

Genome annotation databases

EnsemblBacteriaiACU37020; ACU37020; Amir_3106
KEGGiami:Amir_3106

Similar proteinsi

Entry informationi

Entry nameiC6W7Z9_ACTMD
AccessioniPrimary (citable) accession number: C6W7Z9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: February 28, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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