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UniProtKB - C6KTB4 (C6KTB4_PLAF7)
Protein
Submitted name:
Acetyl-CoA synthetase, putative
Gene
PF3D7_0627800
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
GO - Molecular functioni
- acetate-CoA ligase activity Source: GeneDB
GO - Biological processi
- generation of precursor metabolites and energy Source: GeneDB
Keywordsi
Molecular function | LigaseImported |
Enzyme and pathway databases
Reactomei | R-PFA-71384, Ethanol oxidation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:PF3D7_0627800Imported |
Organismi | Plasmodium falciparum (isolate 3D7)Imported |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | PlasmoDB:PF3D7_0627800 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 59 – 115 | ACAS_NInterPro annotationAdd BLAST | 57 | |
Domaini | 117 – 255 | AMP-bindingInterPro annotationAdd BLAST | 139 | |
Domaini | 530 – 816 | AMP-bindingInterPro annotationAdd BLAST | 287 | |
Domaini | 825 – 863 | AMP-binding_CInterPro annotationAdd BLAST | 39 | |
Domaini | 912 – 948 | AMP-binding_CInterPro annotationAdd BLAST | 37 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 340 – 447 | DisorderedSequence analysisAdd BLAST | 108 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 340 – 421 | Polar residuesSequence analysisAdd BLAST | 82 |
Sequence similaritiesi
Belongs to the ATP-dependent AMP-binding enzyme family.ARBA annotation
Phylogenomic databases
HOGENOMi | CLU_000022_3_2_1 |
InParanoidi | C6KTB4 |
OMAi | DHWWHDL |
PhylomeDBi | C6KTB4 |
Family and domain databases
Gene3Di | 3.30.300.30, 1 hit 3.40.50.12780, 2 hits |
InterProi | View protein in InterPro IPR032387, ACAS_N IPR025110, AMP-bd_C IPR045851, AMP-bd_C_sf IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, ANL_N_sf |
Pfami | View protein in Pfam PF16177, ACAS_N, 1 hit PF00501, AMP-binding, 2 hits PF13193, AMP-binding_C, 2 hits |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
i Sequence
Sequence statusi: Complete.
C6KTB4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNNLKSYGSL SKVDSVQING MDIDTNIFLN MNSYPTKEIY DDENNKNDGN
60 70 80 90 100
HNIKNFQAYK AMYEESINNP EAFWGNLAKN NLIWYKLFTK VFLGNFKKGN
110 120 130 140 150
INWFVNGKIN ACENCVDRWV EKDPNKIALI WEQDCPDQYK KITYQKLLEK
160 170 180 190 200
TCKVANLLKL IGVKKQDTVT IYLPMIPELI YSMLACVRIG AIHNVVFAGY
210 220 230 240 250
SAASLSDRII DSRSTVLITS DFGLRGGKLT KLKQIADVAM DMCGMIQTCI
260 270 280 290 300
VFKNKTKMKD KNIQIKTPME NPIYNFTSFD SNSAQNFTIN NSNDFIQIKS
310 320 330 340 350
THSHQSDHQN DFSLQQEDNN YTKNSNMSYT TSMYYHDNNL NHINTNKNND
360 370 380 390 400
HYNNNLNNKN YLNNNINDQS PMYVHTMNHN DNNDDNNNNN NNNNVDDDNN
410 420 430 440 450
SNIQNDEQSY FNQQNNTYNK NDHSDDNNKN KGKTTLHKKI TKNNPINHKI
460 470 480 490 500
SYSEKSYSKE LINTDMVNND NQFGDLKTKK KFININNIIT CNQNGYSTNK
510 520 530 540 550
QYFPEPDKNS TSNFDETLCV LKKGRDIDGT ALLKNMRSYC PIEYVDSEDF
560 570 580 590 600
LFLLYTSGST GKPKGVAHTT AGYLLYAYTT CKYIFDVKEN DIFGCVADIG
610 620 630 640 650
WVTGHTYVLY GPLLNGITTV IFSSIPTYPD CGRYWSLIQT HKVTQFYTAP
660 670 680 690 700
TALRALMKYG DEWIQKYDLS SCRILGSVGE PINPETWRWY YNVVGKKKCT
710 720 730 740 750
IVDTYWQTET GGIVIAPIPH LFSMKPGCAS LPFLGVQLEI LDSKTLQPLS
760 770 780 790 800
GNNVCGLLCI KSPWPGMLRT VYGNHQRLIK TYFTMCPNYY FTGDGAFRDE
810 820 830 840 850
DGYYWISGRI DDTLNVAGHR LGAAEIEHAL VQHFYIAEAA VVSFHHNVKG
860 870 880 890 900
EGILCFVVKK KGDIKNYSKG ITDIVNSNNN NNRNELHNNS PFLICSNNIT
910 920 930 940 950
DIEEFKKNFT DEKLIEQLKL YVRQVIGPIA TPDLICVVPD LPKTRSGKIV
960 970 980 990
RRILRCIANG ITDFGDISTV SNYEVIETIN NTLIECKKKL KHIEIKK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844505 Genomic DNA Translation: CAG25091.1 |
RefSeqi | XP_966261.1, XM_961168.1 |
Genome annotation databases
EnsemblProtistsi | CAG25091; CAG25091; PF3D7_0627800 |
GeneIDi | 3885698 |
KEGGi | pfa:PF3D7_0627800 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844505 Genomic DNA Translation: CAG25091.1 |
RefSeqi | XP_966261.1, XM_961168.1 |
3D structure databases
SMRi | C6KTB4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 5833.PFF1350c |
Proteomic databases
PRIDEi | C6KTB4 |
Genome annotation databases
EnsemblProtistsi | CAG25091; CAG25091; PF3D7_0627800 |
GeneIDi | 3885698 |
KEGGi | pfa:PF3D7_0627800 |
Organism-specific databases
VEuPathDBi | PlasmoDB:PF3D7_0627800 |
Phylogenomic databases
HOGENOMi | CLU_000022_3_2_1 |
InParanoidi | C6KTB4 |
OMAi | DHWWHDL |
PhylomeDBi | C6KTB4 |
Enzyme and pathway databases
Reactomei | R-PFA-71384, Ethanol oxidation |
Family and domain databases
Gene3Di | 3.30.300.30, 1 hit 3.40.50.12780, 2 hits |
InterProi | View protein in InterPro IPR032387, ACAS_N IPR025110, AMP-bd_C IPR045851, AMP-bd_C_sf IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, ANL_N_sf |
Pfami | View protein in Pfam PF16177, ACAS_N, 1 hit PF00501, AMP-binding, 2 hits PF13193, AMP-binding_C, 2 hits |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | C6KTB4_PLAF7 | |
Accessioni | C6KTB4Primary (citable) accession number: C6KTB4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 1, 2009 |
Last sequence update: | September 1, 2009 | |
Last modified: | January 19, 2022 | |
This is version 85 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |