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UniProtKB - C6KSZ4 (C6KSZ4_PLAF7)

Entry version 57 (10 Feb 2021)
Sequence version 1 (01 Sep 2009)
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Protein
Submitted name:

GPI-anchored wall transfer protein 1, putative

Gene

PF3D7_0615300

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-PFA-162710, Synthesis of glycosylphosphatidylinositol (GPI)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
GPI-anchored wall transfer protein 1, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_0615300Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		PlasmoDB:PF3D7_0615300

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Transmembranei205 – 228HelicalSequence analysisAdd BLAST24
Transmembranei235 – 254HelicalSequence analysisAdd BLAST20
Transmembranei428 – 447HelicalSequence analysisAdd BLAST20
Transmembranei453 – 474HelicalSequence analysisAdd BLAST22
Transmembranei495 – 513HelicalSequence analysisAdd BLAST19
Transmembranei525 – 545HelicalSequence analysisAdd BLAST21
Transmembranei552 – 571HelicalSequence analysisAdd BLAST20
Transmembranei591 – 609HelicalSequence analysisAdd BLAST19
Transmembranei728 – 751HelicalSequence analysisAdd BLAST24
Transmembranei763 – 787HelicalSequence analysisAdd BLAST25
Transmembranei808 – 826HelicalSequence analysisAdd BLAST19
Transmembranei832 – 854HelicalSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		C6KSZ4

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili342 – 376Sequence analysisAdd BLAST35
Coiled coili683 – 706Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_016078_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		C6KSZ4

Identification of Orthologs from Complete Genome Data

More...OMAi		CIFAVDF

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009447, PIGW/GWT1

The PANTHER Classification System

More...PANTHERi		PTHR20661, PTHR20661, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF06423, GWT1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C6KSZ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNMNILAYL LICPFNLIYI FDLPSYIPEL NKKLENDEVF IYGKEIRKNE 
        60         70         80         90        100
SAYSLHYEKY LYELSRRYYE IILKYNKELG VNQEKEYNLI ISREIDKKKK 
       110        120        130        140        150
KQKNSTQGEY NNDDDNNWKL FQIYEKEEPR SYELIRVEIY KKDILLIYKN 
       160        170        180        190        200
EKTKSSIKFI IKKRKDIKNY FSLCYQNCIN KLDKNDYNIL KSTINNSKEN 
       210        220        230        240        250
IINSAYIYMY IIFFFLCIYV EKNLFLYFPI LLQKYEILTT LFILFIPLIL 
       260        270        280        290        300
FVFFYFYFTI IKLICSCLVL YVTFQLIYYT QGMPIYMEHS ILKHKEKEEI 
       310        320        330        340        350
CDEKEEICDE KEEICDEKEE ICDEKEEICD EKEEICDEKE EILDKKKKIH 
       360        370        380        390        400
EKKKKIHDKK EEIDEKKKKI HDKKDESHDK NEDITYPVQY NIENDLWYSS 
       410        420        430        440        450
KNVDIKMYSS SNKGEEYIIQ NTLKHFRLMN MCMTYICIFA VDFYFFPNHF 
       460        470        480        490        500
CKSYYYGNTL MDIGIGASIS SSAYSQEIKK FTYIKEKKRI IELKHIVLFI 
       510        520        530        540        550
LGISRFIGIY LFNYNYNISE YGIHWNFFLT LCTTFLISNI CFILLKRIRY 
       560        570        580        590        600
IFLFSIISII LFEIAIYYFD LHNYILLKND RLNFFSSNKE GLFNIIGSVN 
       610        620        630        640        650
LYLFSFSLFK YLTKQRTYIT TSNIPKNKKD MNNSMYSKNG NHTNSNINNR 
       660        670        680        690        700
NHKIVIRNNH INKYEQDNTN KYINKQINNN KNKLDEEEKL KKLKKLKNKK 
       710        720        730        740        750
KNLKKKIKYY LLYLQYIINI YKEEYYTIYY NIKLIISSFI FYLLHIILNL 
       760        770        780        790        800
YKNYSVRILC NANYIFLITS LGLFSCALSF SLEDILLRYK KYKINIDITV 
       810        820        830        840        850
LDKINKNTLI VFLFSNILVG MFNILFQTLL LPLIFVIPIL VFYSFLILLF 
       860        870 
TKCLPPSIRH PKKKTHHEEK QKKE
Length:874
Mass (Da):105,757
Last modified:September 1, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6D305275081E36D7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL844505 Genomic DNA Translation: CAG25391.1

NCBI Reference Sequences

More...RefSeqi		XP_966139.1, XM_961046.1

Genome annotation databases

Ensembl protists genome annotation project

More...EnsemblProtistsi		CAG25391; CAG25391; PF3D7_0615300

GeneDB pathogen genome database from Sanger Institute

More...GeneDBi		PF3D7_0615300.1:pep

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3885865

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pfa:PF3D7_0615300

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844505 Genomic DNA Translation: CAG25391.1
RefSeqiXP_966139.1, XM_961046.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PRIDEiC6KSZ4

Genome annotation databases

EnsemblProtistsiCAG25391; CAG25391; PF3D7_0615300
GeneDBiPF3D7_0615300.1:pep
GeneIDi3885865
KEGGipfa:PF3D7_0615300

Organism-specific databases

VEuPathDBiPlasmoDB:PF3D7_0615300

Phylogenomic databases

HOGENOMiCLU_016078_0_0_1
InParanoidiC6KSZ4
OMAiCIFAVDF

Enzyme and pathway databases

ReactomeiR-PFA-162710, Synthesis of glycosylphosphatidylinositol (GPI)

Family and domain databases

InterProiView protein in InterPro
IPR009447, PIGW/GWT1
PANTHERiPTHR20661, PTHR20661, 1 hit
PfamiView protein in Pfam
PF06423, GWT1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC6KSZ4_PLAF7
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C6KSZ4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 10, 2021
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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