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Entry version 76 (07 Apr 2021)
Sequence version 1 (01 Sep 2009)
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Protein

Probable DNA repair protein RAD50

Gene

PFF0285c

Organism
Plasmodium falciparum (isolate 3D7)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity).By similarity

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi34 – 41ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processCell cycle, DNA damage, DNA repair, Meiosis
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable DNA repair protein RAD50
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PFF0285c
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaSarAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
PlasmoDB:PF3D7_0605800

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome, Nucleus, Telomere

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the use of a specific protein in the biotechnological industry.<p><a href='/help/biotechnological_use' target='_top'>More...</a></p>Biotechnological usei

Possible candidate for an effective malaria vaccine as determined by epitope response in sera.

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003715001 – 2236Probable DNA repair protein RAD50Add BLAST2236

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
C6KSQ6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Keywords - Developmental stagei

Merozoite

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Probable component of the MRN complex with MRE11.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
1210379, 2 interactors

Protein interaction database and analysis system

More...
IntActi
C6KSQ6, 3 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
C6KSQ6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 2230Zinc-hookAdd BLAST2228

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili223 – 244Sequence analysisAdd BLAST22
Coiled coili288 – 381Sequence analysisAdd BLAST94
Coiled coili634 – 724Sequence analysisAdd BLAST91
Coiled coili906 – 930Sequence analysisAdd BLAST25
Coiled coili968 – 997Sequence analysisAdd BLAST30
Coiled coili1089 – 1170Sequence analysisAdd BLAST82
Coiled coili1376 – 1403Sequence analysisAdd BLAST28
Coiled coili1606 – 1626Sequence analysisAdd BLAST21
Coiled coili1778 – 1839Sequence analysisAdd BLAST62
Coiled coili1970 – 2006Sequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi491 – 576Asn-richAdd BLAST86
Compositional biasi600 – 683Lys-richAdd BLAST84
Compositional biasi846 – 1397Lys-richAdd BLAST552
Compositional biasi1215 – 1351Asn-richAdd BLAST137
Compositional biasi1516 – 1615Asp-richAdd BLAST100
Compositional biasi1670 – 1839Lys-richAdd BLAST170
Compositional biasi1882 – 1960Asn-richAdd BLAST79

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The zinc-hook, which separates the large intramolecular coiled coil regions, contains 2 Cys residues that coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another RAD50 molecule, thereby forming a V-shaped homodimer. The two heads of the homodimer, which constitute the ATP-binding domain, interact with the MRE11 homodimer (By similarity).By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SMC family. RAD50 subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002217_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C6KSQ6

Identification of Orthologs from Complete Genome Data

More...
OMAi
NVILCHH

Database for complete collections of gene phylogenies

More...
PhylomeDBi
C6KSQ6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417, P-loop_NTPase
IPR038729, Rad50/SbcC_AAA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13476, AAA_23, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C6KSQ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTLEKIGIQ GIRSYNDEDV EILEFATPIT IIYGNNGSGK STIIECLKVS
60 70 80 90 100
CTGDFPPNAE KGKSFLHDPL ISNKMNIRGK IDVLLNNYNN KRIGISRSYN
110 120 130 140 150
LFYSKDKNKK VKHTFRALDN NIIIKKEKGD DLIITNKCVD INNHIPKLMG
160 170 180 190 200
VSKALLENVI FCHHDENLWP FSESIKIKKK FDELFGDDHF SKILEELLKC
210 220 230 240 250
KKYLNDLLKR KEFDLIHIKE NFEKKKNIYI EIEKNEKEIQ SAQICIQLDV
260 270 280 290 300
EEIEENTIIL NNLIKKKNLL YKLIGNIDSY FLLYTKFKVD AEAYKDLKEV
310 320 330 340 350
YEENYTELLY FQEVFNNDIN KCEICIQKVK QDIQNLQHEK DTCMFNYNES
360 370 380 390 400
NKYDDNYELS KKQLNEYIIK RDDIRNKLKD IFFYNDQIFF SNYKGNSSSD
410 420 430 440 450
MIKHSSINEG HQKEKLKKKF KKHDSVYIKD HLLKEYENLL HMYDIHKEDI
460 470 480 490 500
ALYNHDVMLS YKNEEHIPSN ARLMEELFLI CQNKVQYKTS NKSDDNKRNN
510 520 530 540 550
NNNHFDDDNK RNNNNNHFDD DNKRNNNNNH FDDDNKRNNN NNHFDDDNKR
560 570 580 590 600
NNNNNHFDDD NKRNNNNNHF DDDNKNKCDD KKFIEIPNVS NILSNVPYLK
610 620 630 640 650
KKHEKKINSI RYILKRHISH IKRNKYKKRN VIYKIKNYKK RLLKIEKNIT
660 670 680 690 700
LLDIYKNKLN KLKSNEIIYE QNLKKIEKLN QLKCLYDNLT TLDNEMDTYN
710 720 730 740 750
IQKENNYYEE QIEKNMKQIN DIQKLKIWIH TFCNIIRNYN IFYEFIQRCK
760 770 780 790 800
KIHEHCVIFF DILFSLLDVI KTDFYKIVDM LKERDMDLYY YIERGMQKKI
810 820 830 840 850
NVERNVCVER NVCVERNVCV ENNICVEKNI CVEKNICGEK NICGEKKKIT
860 870 880 890 900
KLKSNIEIEE SVEKIKDNKI NECDVNVDTL NKTNSIHHVN NIKINSKSLV
910 920 930 940 950
CMNEHLQRKR ENEKLNDYTC KLKKQKTHLD ISILKNRKYL DILLNIINIF
960 970 980 990 1000
IDKYENKINN IKTLIIPLNQ KVLEISKKLN NMNNNINEYK NYLSNFIHML
1010 1020 1030 1040 1050
KEKKYKDVKD FVNYVEAIDN QIKIKKKNLW MLNGKEDLMN EFKNHLKSDE
1060 1070 1080 1090 1100
QNNSDNNKKV GVEKKKKKNC LFCKNTISQN NKDIVQIEMY IEEQKRDMLK
1110 1120 1130 1140 1150
KIEESEKDIN ILKNKKEENI ILLNYYYYHI KHIHTYTNDS NEMIVKLKEE
1160 1170 1180 1190 1200
LLSAQDSIEK YNIKIKNIHR KFQLVQKFKE TCVYLINIQK DILDVEKYIK
1210 1220 1230 1240 1250
DESIKIKGNF QEMKNKIKDN VENNKMSNNT NKCNDTKTCN NTKTCNNTYT
1260 1270 1280 1290 1300
CDHLFIEKLY HMIENLDISI EVKESNLLKN IKEFVKKFAK YNNKDIINIF
1310 1320 1330 1340 1350
YNKICTSNVN DSYSYIPYND IINVDLYQQY NYQNNYKNRF KYNLYKINNA
1360 1370 1380 1390 1400
NYICKLLSPH QKVSLKDCYS SDQTPQKIYV DEEKEKEKEK KKKKKKKTDN
1410 1420 1430 1440 1450
DGYYDEIFHC DNMEYDEQFY EDDDHHSYNK SKSLIENYIT PCKNKEESVK
1460 1470 1480 1490 1500
EPNMCSIKHI YDNGSSNDDI LNNDKTVLLN KINSSYLSFV LNIGTSYYSN
1510 1520 1530 1540 1550
EEIKENNKND TNKMCDDTNK MCDDTNKMYD DTNKMYDDTN KMYDDTNKMY
1560 1570 1580 1590 1600
DDTNKMCDDT NKRYDDTNKM CHDTNKMCDD TNQMYDDTNK RYDDTNKRYD
1610 1620 1630 1640 1650
DTNKMCDDTN QMYDDTNKRY DNINQNTYGT FLKCSDFLHN LPSIILNNKH
1660 1670 1680 1690 1700
FEKMYRNFLS YLNVEEYTRK EQNKMIEKMK VVIKDRRAYV IKKSKVLEKT
1710 1720 1730 1740 1750
INIDKRIRDL IKKMDIYILY YKEKKKKIID EKINVKNLLI EQRDTQLKYI
1760 1770 1780 1790 1800
KRCIRNNKKS IFLEKRNYYL KMNMIYILIK KLKHTEEEIV NKEKYLKDVK
1810 1820 1830 1840 1850
EKLNNNEIIK NQVICIDKKI NEKKEHILCL EKEKINIEKM LHNIIMNTNM
1860 1870 1880 1890 1900
KKMYEQFLEH HQTFILSLNQ LKASFFLYER KNIKNSNMCK LEYKDEINGD
1910 1920 1930 1940 1950
KKKENDNTVS SNNDSIINND NRNKKNRYND EENGINYIND IVKKLEENYN
1960 1970 1980 1990 2000
NNTNIYNFIN KTFDITDCLK NRLKDIIKIE EDDLNEQIEK YTKSITALKI
2010 2020 2030 2040 2050
KEAEMNGKIC LRKEYLEKLK EDIKSETLIN IDKEYKKKII EIFVYKNLIK
2060 2070 2080 2090 2100
DLQNFHFSFD QAIIKFHSLK MQEINLSIKN LWRRVYNSAD IDYIYIKSDI
2110 2120 2130 2140 2150
QTEPTDKSSQ RRSYNYRVVM VKDNCELDMK GRCSSGQKVL SSIIIRLALA
2160 2170 2180 2190 2200
ESFSIKCGIL ALDEPTTNLD KANSRNLASL LANIVELRKS SSSFQLILIT
2210 2220 2230
HDNYFVDILS QYGLTNCFYK IKKNNLGYSK IERVNT
Length:2,236
Mass (Da):267,956
Last modified:September 1, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3ADA116F6716B875
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL844505 Genomic DNA Translation: CAG25228.1

NCBI Reference Sequences

More...
RefSeqi
XP_966048.1, XM_960955.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAG25228; CAG25228; PF3D7_0605800

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
PF3D7_0605800.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3885706

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pfa:PF3D7_0605800

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844505 Genomic DNA Translation: CAG25228.1
RefSeqiXP_966048.1, XM_960955.1

3D structure databases

SMRiC6KSQ6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi1210379, 2 interactors
IntActiC6KSQ6, 3 interactors

Proteomic databases

PRIDEiC6KSQ6

Genome annotation databases

EnsemblProtistsiCAG25228; CAG25228; PF3D7_0605800
GeneDBiPF3D7_0605800.1:pep
GeneIDi3885706
KEGGipfa:PF3D7_0605800

Organism-specific databases

VEuPathDBiPlasmoDB:PF3D7_0605800

Phylogenomic databases

HOGENOMiCLU_002217_0_0_1
InParanoidiC6KSQ6
OMAiNVILCHH
PhylomeDBiC6KSQ6

Family and domain databases

InterProiView protein in InterPro
IPR027417, P-loop_NTPase
IPR038729, Rad50/SbcC_AAA
PfamiView protein in Pfam
PF13476, AAA_23, 1 hit
SUPFAMiSSF52540, SSF52540, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRAD50_PLAF7
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C6KSQ6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: April 7, 2021
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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