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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Geobacter sp. (strain M21)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGSP443144:G1GFA-1959-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:GM21_1940
OrganismiGeobacter sp. (strain M21)
Taxonomic identifieri443144 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000002380 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002030961 – 554Arginine--tRNA ligaseAdd BLAST554

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi443144.GM21_1940

Structurei

3D structure databases

ProteinModelPortaliC6E805
SMRiC6E805
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi129 – 139"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

C6E805-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKEQLRACIL KGIEGCFADG TLTSGEVPAI NVEKPAHAEH GDFATNVAMQ
60 70 80 90 100
MAKQQRKAPR AVAEILVAKL AGASDLIESL EIAGPGFINF FIKDGAWRRT
110 120 130 140 150
LSEIDRAGDA WGKSGIGRGK KVQVEFVSAN PTGPLHIGHG RGAATGDAVA
160 170 180 190 200
SLLSAAGFDV QREYYINDAG NQMNTLGLSG LLRYKELLGE KIEFPETCYQ
210 220 230 240 250
GDYMKDIARD AVTKYGDRFL KVSQEEGVAF FSKMGGDLIL AGIDQDLQDF
260 270 280 290 300
GVRFDHWFSE QSLFDEGKVN SAIEEMQAKG LIYEQEGALW FRTTDYGDDK
310 320 330 340 350
DRVVVRSNGV TTYFASDIAY HRDKFARGFD WVIDVWGADH HGYVPRLKSV
360 370 380 390 400
VQGLGRDASD LGIILVQLVS LLRDGVPVAM STRSGEFVTL KEVVDEVGRD
410 420 430 440 450
AARFFFLMRR SDSQLDFDLE LAKRQSNDNP VYYVQYAHAR IKSIFDTARE
460 470 480 490 500
RGVEPLFDSV KFELLQTPED LSLIKKLSVY PEILEGGAVN FEPHRITYYL
510 520 530 540 550
QELAGEFHSF YNKSRVITPE EPELTQARLF LLHCVAITLK NALTVLGISA

PERM
Length:554
Mass (Da):61,613
Last modified:September 1, 2009 - v1
Checksum:iCE5D9D08691939BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA Translation: ACT17993.1
RefSeqiWP_015837237.1, NC_012918.1

Genome annotation databases

EnsemblBacteriaiACT17993; ACT17993; GM21_1940
KEGGigem:GM21_1940

Similar proteinsi

Entry informationi

Entry nameiSYR_GEOSM
AccessioniPrimary (citable) accession number: C6E805
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: February 28, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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