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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Geobacter sp. (strain M21)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei76NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciGSP443144:G1GFA-1468-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:GM21_1445
OrganismiGeobacter sp. (strain M21)
Taxonomic identifieri443144 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000002380 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002135141 – 398tRNA pseudouridine synthase DAdd BLAST398

Interactioni

Protein-protein interaction databases

STRINGi443144.GM21_1445

Structurei

3D structure databases

ProteinModelPortaliC6E4K4
SMRiC6E4K4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 361TRUDUniRule annotationAdd BLAST211

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 1 hit
PfamiView protein in Pfam
PF01142 TruD, 1 hit
PIRSFiPIRSF037016 Pseudouridin_synth_euk_prd, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

C6E4K4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIYLTAEVP GTGGVIKATP EDFLVEEIPA YLPSGQGEHC FAVLEKRGIA
60 70 80 90 100
TLEALRRLAK ALGVQERDLG YAGMKDAIGI TRQTISIPRV APEKVLALEI
110 120 130 140 150
PGITVLSASM HGNKLRLGHL KGNRFVIRVR DVAQGAAGNA EAALEIMTRR
160 170 180 190 200
GVPNRFGVQR YGAQGNTHEI GAAMLRREFK SAVDRLIGDP AAVTDERWRL
210 220 230 240 250
AIEAYRRGEV AESLALFPGH FRVERELLTR LVQRPDGFER AFNSVQPRMK
260 270 280 290 300
RLYLSAFQSS LFDLVLGKRL DSFDQVNVGD IAFKHENGAC FLVQDLAAEA
310 320 330 340 350
PRAESFEISP TGPMFGCTMM ESHGAQGELE REVLAAQELT LESFNLSGGL
360 370 380 390
RMEGERRPLR VPIAGAEVRQ DGSDLLLDFS LPRGAYATCV LSEIMKSD
Length:398
Mass (Da):43,619
Last modified:September 1, 2009 - v1
Checksum:iE8FCDFC20FDC3401
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA Translation: ACT17502.1
RefSeqiWP_015836753.1, NC_012918.1

Genome annotation databases

EnsemblBacteriaiACT17502; ACT17502; GM21_1445
KEGGigem:GM21_1445

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA Translation: ACT17502.1
RefSeqiWP_015836753.1, NC_012918.1

3D structure databases

ProteinModelPortaliC6E4K4
SMRiC6E4K4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi443144.GM21_1445

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT17502; ACT17502; GM21_1445
KEGGigem:GM21_1445

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Enzyme and pathway databases

BioCyciGSP443144:G1GFA-1468-MONOMER

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 1 hit
PfamiView protein in Pfam
PF01142 TruD, 1 hit
PIRSFiPIRSF037016 Pseudouridin_synth_euk_prd, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_GEOSM
AccessioniPrimary (citable) accession number: C6E4K4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: November 7, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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