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Entry version 47 (17 Jun 2020)
Sequence version 1 (01 Sep 2009)
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Protein
Submitted name:

Uncharacterized protein

Gene

Rpic12D_0802

Organism
Ralstonia pickettii (strain 12D)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
RPIC428406:GH9Y-798-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Rpic12D_0802Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRalstonia pickettii (strain 12D)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri428406 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008208 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei6 – 39HelicalSequence analysisAdd BLAST34
Transmembranei185 – 204HelicalSequence analysisAdd BLAST20
Transmembranei216 – 233HelicalSequence analysisAdd BLAST18
Transmembranei240 – 259HelicalSequence analysisAdd BLAST20
Transmembranei265 – 286HelicalSequence analysisAdd BLAST22
Transmembranei293 – 311HelicalSequence analysisAdd BLAST19
Transmembranei317 – 336HelicalSequence analysisAdd BLAST20
Transmembranei341 – 360HelicalSequence analysisAdd BLAST20
Transmembranei372 – 390HelicalSequence analysisAdd BLAST19
Transmembranei402 – 420HelicalSequence analysisAdd BLAST19
Transmembranei426 – 446HelicalSequence analysisAdd BLAST21
Transmembranei453 – 475HelicalSequence analysisAdd BLAST23
Transmembranei481 – 496HelicalSequence analysisAdd BLAST16
Transmembranei503 – 527HelicalSequence analysisAdd BLAST25
Transmembranei539 – 556HelicalSequence analysisAdd BLAST18
Transmembranei568 – 586HelicalSequence analysisAdd BLAST19
Transmembranei609 – 626HelicalSequence analysisAdd BLAST18
Transmembranei638 – 657HelicalSequence analysisAdd BLAST20
Transmembranei663 – 681HelicalSequence analysisAdd BLAST19
Transmembranei693 – 715HelicalSequence analysisAdd BLAST23
Transmembranei727 – 746HelicalSequence analysisAdd BLAST20
Transmembranei758 – 777HelicalSequence analysisAdd BLAST20
Transmembranei789 – 812HelicalSequence analysisAdd BLAST24
Transmembranei824 – 844HelicalSequence analysisAdd BLAST21
Transmembranei864 – 885HelicalSequence analysisAdd BLAST22
Transmembranei892 – 910HelicalSequence analysisAdd BLAST19
Transmembranei922 – 939HelicalSequence analysisAdd BLAST18

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni49 – 74DisorderedSequence analysisAdd BLAST26

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili81 – 101Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006561_0_0_4

Identification of Orthologs from Complete Genome Data

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OMAi
IFAIAWF

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019286, DUF2339_TM
IPR014600, UCP035905_mem

The PANTHER Classification System

More...
PANTHERi
PTHR38434, PTHR38434, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10101, DUF2339, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF035905, UCP035905_mp, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C6BER6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRWIFGIVGL LLGGLSGGVI GAFFGALIGL GLASLILYMD KRASAQWANP
60 70 80 90 100
PDVPGATSAA PGHAATQAAV SPPPATLQER VARLEHEVSL LRRQLAEMKG
110 120 130 140 150
GTFVAPADVE QAAAEVPPVV AEALPPVDTP AVPVPVSMPA PQVAVPQPMP
160 170 180 190 200
QSAAQPVPVL APHEPDWVER AVGAARDWLL GGNSVVRVGI LVLFFGVAFL
210 220 230 240 250
LKYAADNSLL PVEFRLAGVA VGAIVLLGIG WRLREKRPGY ALVLQGGGVG
260 270 280 290 300
VLYLTVFAAT RVVPLLSPGM AFPLLVLICA LAAGLAVKQN APALAFTGSA
310 320 330 340 350
GGFLAPILIS TGQGSHVALF SYYALLNAGI FAIAWFRAWR ALNLLGFVFT
360 370 380 390 400
FGIATAWGVL RYQPSLLAST EPFLILFFLM YVGIALLTAL RRHVSLTNYV
410 420 430 440 450
DGTLVFGTPL VAMGLQTGLV HHIPFAMAWS ATALAAFYLG IAGWLARRRA
460 470 480 490 500
SLGLLYEAMF ALGVIFITLA IPLAFDGRTT SAVWALEGAA VVWLGVRQQR
510 520 530 540 550
RLALAAGVLL QLAAGAAFAV DAAFDWAPQH GWAVLNSRYI GGVLIALAGV
560 570 580 590 600
FSGWRLHGKA EARTWLKAAP VLGIAASVWG LLWWLGSGSN EIDRWAWRIA
610 620 630 640 650
TKTVDRPDIP LYAAFAVLTA WAAHGLRRKL AWALAEWPAL ALSPVLALIS
660 670 680 690 700
LAAIEHWAPS PLAGWGGLVW IAAVVLTFVL LHRQQHDVKD RILAPLHTVL
710 720 730 740 750
FWLICGLLAT EGYWRLDAYV PEGTWSFAAW AYAYGALLAL LAGAGWRIRW
760 770 780 790 800
PIARFERAYL LWGAAPLTAL LWLWSLASAA SDGNAAPLFY LPILNPLDVA
810 820 830 840 850
QLLVFFAIAL WMRRVALQKL VPEPMVIGYA IGATLFIWAN AVLLRTLHHW
860 870 880 890 900
AHVPYTLDDL GASMLVQASL SMFWTVLALA VMVFATRRAS RALWFTGGAL
910 920 930 940 950
LGVTVVKLFL FDLSRVTGVE RIVSFIAIGV LLLLIGYLSP LPPKPKTSAD

AGTGEVL
Length:957
Mass (Da):102,339
Last modified:September 1, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D527DA80BC11AA5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001644 Genomic DNA Translation: ACS62103.1

NCBI Reference Sequences

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RefSeqi
WP_012761519.1, NC_012856.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACS62103; ACS62103; Rpic12D_0802

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rpf:Rpic12D_0802

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001644 Genomic DNA Translation: ACS62103.1
RefSeqiWP_012761519.1, NC_012856.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiACS62103; ACS62103; Rpic12D_0802
KEGGirpf:Rpic12D_0802

Phylogenomic databases

HOGENOMiCLU_006561_0_0_4
OMAiIFAIAWF

Enzyme and pathway databases

BioCyciRPIC428406:GH9Y-798-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR019286, DUF2339_TM
IPR014600, UCP035905_mem
PANTHERiPTHR38434, PTHR38434, 1 hit
PfamiView protein in Pfam
PF10101, DUF2339, 1 hit
PIRSFiPIRSF035905, UCP035905_mp, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC6BER6_RALP1
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C6BER6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: June 17, 2020
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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