UniProtKB - C5DYW2 (C5DYW2_ZYGRC)
Protein
Peptidyl-prolyl cis-trans isomerase
Gene
ZYRO0F16214g
Organism
Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) (Candida mogii)
Status
Functioni
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotationARBA annotation
Catalytic activityi
- [protein]-peptidylproline (ω=180) = [protein]-peptidylproline (ω=0)UniRule annotationARBA annotationEC:5.2.1.8UniRule annotationARBA annotation
GO - Molecular functioni
- peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-UniRule
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- regulation of phosphorylation of RNA polymerase II C-terminal domain Source: EnsemblFungi
Keywordsi
Molecular function | Isomerase, RNA-bindingPROSITE-ProRule annotation, RotamaseUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)Short name: PPIaseUniRule annotation |
Gene namesi | Ordered Locus Names:ZYRO0F16214gImported |
Organismi | Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) (Candida mogii)Imported |
Taxonomic identifieri | 559307 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Zygosaccharomyces › |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- nuclear chromatin Source: EnsemblFungi
Keywords - Cellular componenti
NucleusUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 175 | PPIase cyclophilin-typeInterPro annotationAdd BLAST | 170 | |
Domaini | 242 – 320 | RRMInterPro annotationAdd BLAST | 79 |
Sequence similaritiesi
Phylogenomic databases
HOGENOMi | CLU_018791_2_0_1 |
InParanoidi | C5DYW2 |
Family and domain databases
Gene3Di | 2.40.100.10, 1 hit 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR035542, CRIP IPR029000, Cyclophilin-like_dom_sf IPR002130, Cyclophilin-type_PPIase_dom IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR45843, PTHR45843, 1 hit |
Pfami | View protein in Pfam PF00160, Pro_isomerase, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF50891, SSF50891, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50072, CSA_PPIASE_2, 1 hit PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Complete.
C5DYW2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSVLLETTAG DIIVDLKYKQ YEIESYNFLK LCKCNFYQNQ CFYNLHKDQS
60 70 80 90 100
VQFGNPLLGY EDRKELRLKN TSVEGITSEP VKSRLLKATE SPDRSGKALK
110 120 130 140 150
GSLGNVVVQK QESGQELIGS QVIISLAEHG LDATNAIYFG DVIQTSWSTL
160 170 180 190 200
DKIERFAVDD TQRPIEDIRI RSTFIIYDPF LDGRHFPTYE VSLPIQDIRL
210 220 230 240 250
PQTLVDEFTD EDPEVRRDIK RKELSLEIIE NMPIMGIKPS PRVLFICKLN
260 270 280 290 300
PLTRAKDIAT IFQRFGAIAS VEIVRDKSTG HSLGYGFIQF TDRKSCEQAY
310 320 330
KKMEGVIIDD RRIHVDFSQS VKAATKAINR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU928178 Genomic DNA Translation: CAR28973.1 |
RefSeqi | XP_002497906.1, XM_002497861.1 |
Genome annotation databases
EnsemblFungii | CAR28973; CAR28973; ZYRO0F16214g |
GeneIDi | 8205678 |
KEGGi | zro:ZYRO0F16214g |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU928178 Genomic DNA Translation: CAR28973.1 |
RefSeqi | XP_002497906.1, XM_002497861.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblFungii | CAR28973; CAR28973; ZYRO0F16214g |
GeneIDi | 8205678 |
KEGGi | zro:ZYRO0F16214g |
Phylogenomic databases
HOGENOMi | CLU_018791_2_0_1 |
InParanoidi | C5DYW2 |
Family and domain databases
Gene3Di | 2.40.100.10, 1 hit 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR035542, CRIP IPR029000, Cyclophilin-like_dom_sf IPR002130, Cyclophilin-type_PPIase_dom IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR45843, PTHR45843, 1 hit |
Pfami | View protein in Pfam PF00160, Pro_isomerase, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF50891, SSF50891, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50072, CSA_PPIASE_2, 1 hit PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C5DYW2_ZYGRC | |
Accessioni | C5DYW2Primary (citable) accession number: C5DYW2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 28, 2009 |
Last sequence update: | July 28, 2009 | |
Last modified: | December 2, 2020 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |