Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 57 (16 Oct 2019)
Sequence version 1 (28 Jul 2009)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

KLTH0D13156p

Gene

KLTH0D13156g

Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
KLTH0D13156pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:KLTH0D13156gImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559295 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeLachancea
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002036 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome D

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
381046.XP_002553282.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini511 – 581S1 motifInterPro annotationAdd BLAST71
Domaini608 – 677S1 motifInterPro annotationAdd BLAST70
Domaini691 – 770S1 motifInterPro annotationAdd BLAST80
Domaini795 – 864S1 motifInterPro annotationAdd BLAST70
Domaini898 – 974S1 motifInterPro annotationAdd BLAST77
Domaini1004 – 1076S1 motifInterPro annotationAdd BLAST73
Domaini1089 – 1160S1 motifInterPro annotationAdd BLAST72
Domaini1178 – 1246S1 motifInterPro annotationAdd BLAST69
Domaini1266 – 1337S1 motifInterPro annotationAdd BLAST72

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 42DisorderedSequence analysisAdd BLAST42
Regioni66 – 102DisorderedSequence analysisAdd BLAST37
Regioni166 – 195DisorderedSequence analysisAdd BLAST30
Regioni864 – 883DisorderedSequence analysisAdd BLAST20
Regioni1343 – 1406DisorderedSequence analysisAdd BLAST64
Regioni1419 – 1450DisorderedSequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 17PolyampholyteSequence analysisAdd BLAST17
Compositional biasi18 – 33PolarSequence analysisAdd BLAST16
Compositional biasi167 – 187AcidicSequence analysisAdd BLAST21
Compositional biasi1350 – 1382AcidicSequence analysisAdd BLAST33
Compositional biasi1430 – 1447PolyampholyteSequence analysisAdd BLAST18

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000167551

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C5DF89

KEGG Orthology (KO)

More...
KOi
K14792

Identification of Orthologs from Complete Genome Data

More...
OMAi
GQYLRAY

Database of Orthologous Groups

More...
OrthoDBi
23482at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003107 HAT
IPR012340 NA-bd_OB-fold
IPR022967 S1_dom
IPR003029 S1_domain
IPR008847 Suf
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00575 S1, 3 hits
PF05843 Suf, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00386 HAT, 6 hits
SM00316 S1, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 2 hits
SSF50249 SSF50249, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50126 S1, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C5DF89-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSGQKRKR VEESPLTRQD NTKQPSGPSL LQSVEEASFP RGGASALTPL
60 70 80 90 100
ELKQVANEAA SDVLFGSGPA VASPAANDSQ RPKKKKKTSP KAATGTKDAA
110 120 130 140 150
GGDDESVAVI DHLTFRNLPV GTLVLGRISK VNKHDLCVAL SDNLCGFVTL
160 170 180 190 200
PNISEPFTKL LEDIDESMES DKEASDDESD AEYDNDDDDQ KSSQAQAAKL
210 220 230 240 250
KDLPDLNNFF TQGQWLRCSV HSNSALDKNS KKQKRIELSI EPSATNQLIE
260 270 280 290 300
EDLARNCTIQ CAVKSIEDHG AILDVGMDGI TGFISKKECE SLPNFAPGTV
310 320 330 340 350
FLANVAKKSG RTVTVNFEFK NKKSKVSQIS SVDAVIPGQA VDFLCQKKTS
360 370 380 390 400
NGVIGKVFGL VDGFLNISQQ AIFYTDSKSD QAYPIGSNTR VRIIASLKNK
410 420 430 440 450
SGDKFVILSD LPSVLSLASE TSGNSALEAF PVGYTFENCE VKGRDSQYFY
460 470 480 490 500
LKLNKDFLGR VHLSKTGEQE PSGEVSARVL GYDSFDGYYQ LATDPKVIAV
510 520 530 540 550
EYLRPIDIPV GTIVPGCEIT EVSDKGIKLS IFGGQFKATV PPLHISDIRL
560 570 580 590 600
VYPERKFKIG SKVKGILINA TERGQLFMSL KKSLVNLDRE ETELASSFED
610 620 630 640 650
IEKIASSDSK LAATVDIFKP NGCIVSFLNG LRGFLPNSNI SEAYVKRPQD
660 670 680 690 700
HLRLGQTVIV KVLQHNKEQN RVIVTCKVSS EAASLQREAI ENMIVGRSII
710 720 730 740 750
KVAVVEKTKD SIVVEQVGTG LRGVVYVGHL SDSRVEQNRA QLKKLKIGSE
760 770 780 790 800
LEGLVIDKDE RTRVFNLSCK KSLMKDAEKS LLPLNYQDVK QRGNHSPFNG
810 820 830 840 850
YVKSVSEKGV FVAFNGQFVG LVLPSYAVDS RDVSLSSKFY VNQSVSAFLL
860 870 880 890 900
RTDDDNERFL LSFKEPKNEK SSKTPESERP AINPVDQSIK EVSEFALGKV
910 920 930 940 950
TKAKVKAVKK NQLNVVLSDN LHGRIDISEV FDKFEDIKDP KKPLATFKKG
960 970 980 990 1000
DVLDVKVIGF HDVKSHKFLP VSHRSSKNVL IELSAKPSSL AGVNHATIKD
1010 1020 1030 1040 1050
VKVGDSIVGF VNNVSKDIMW LTVSPSLKAK IDFFDLADEN SQLGHGIEDS
1060 1070 1080 1090 1100
FPLGCALRTK VVSIDQDRNT LSVSARTHDI KGIKDINVGD CLPARLLKIT
1110 1120 1130 1140 1150
DSYLLLELGE NVRGVAFATD ALDDYSKPLK DVYANQKNSI VSAKVISIDK
1160 1170 1180 1190 1200
DDGKLNLSLR SENPRDGTAK THEDLKRGDV VRGLVKKITE KGIFIYLSST
1210 1220 1230 1240 1250
LQAFVPVSKL TDSFIKDWRK FFKPMQSVVG KVVNCDDDSH ILVTLKESEV
1260 1270 1280 1290 1300
NGELRILKSY NDIKVGEIFE GAVKNVTDFG LFVKLDNTVN VTGLAHKTEV
1310 1320 1330 1340 1350
ADSAVGDLAS IFGVGDKVKA IVLKVNPDKK QLSLGLKASY FKESNENQAS
1360 1370 1380 1390 1400
DDAEGDEGSE SSDEEVVNEE GQESDSDGME VDDHEGEDKG DKSKQQPVLS
1410 1420 1430 1440 1450
SDGLSLSAGF DWTTSILDQA QEEESSEEED FSETKRSKKK KKSVQGVEDQ
1460 1470 1480 1490 1500
TIDINTRAPE SVGDFERMIM GNPNSSVIWM NYMAFQLQLG EIDKAREVAE
1510 1520 1530 1540 1550
RALKTISFRE EAEKLNIWIG LLNLENTFGT ESTLNEVFSR ACQYMDSYTI
1560 1570 1580 1590 1600
HSKLINIFQM SHNFEKASLL FKTTAKKFGA EKVSIWVLWS DFLIEQGRAE
1610 1620 1630 1640 1650
EARQVLASAL QSLPRRNHIE VVRKFAQLEF AKGDSEQGRS LFEGLLADTP
1660 1670 1680 1690 1700
KRIDLWNVYL DQEIKSGDKK RVENLFERVV NRKLTRKQAK FFFGKWLDFE
1710 1720 1730
EASDDQKTAE YVKAKASEYV EKLSQKSASV E
Length:1,731
Mass (Da):191,147
Last modified:July 28, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFB1951C6EE113324
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU928168 Genomic DNA Translation: CAR22844.1

NCBI Reference Sequences

More...
RefSeqi
XP_002553282.1, XM_002553236.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
CAR22844; CAR22844; KLTH0D13156g

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8295524

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
lth:KLTH0D13156g

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928168 Genomic DNA Translation: CAR22844.1
RefSeqiXP_002553282.1, XM_002553236.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi381046.XP_002553282.1

Genome annotation databases

EnsemblFungiiCAR22844; CAR22844; KLTH0D13156g
GeneIDi8295524
KEGGilth:KLTH0D13156g

Phylogenomic databases

HOGENOMiHOG000167551
InParanoidiC5DF89
KOiK14792
OMAiGQYLRAY
OrthoDBi23482at2759

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR003107 HAT
IPR012340 NA-bd_OB-fold
IPR022967 S1_dom
IPR003029 S1_domain
IPR008847 Suf
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF00575 S1, 3 hits
PF05843 Suf, 1 hit
SMARTiView protein in SMART
SM00386 HAT, 6 hits
SM00316 S1, 13 hits
SUPFAMiSSF48452 SSF48452, 2 hits
SSF50249 SSF50249, 11 hits
PROSITEiView protein in PROSITE
PS50126 S1, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC5DF89_LACTC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C5DF89
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: October 16, 2019
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again