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Entry version 55 (12 Aug 2020)
Sequence version 1 (28 Jul 2009)
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Protein
Submitted name:

Type VI secretion system Vgr family protein

Gene

Vapar_0531

Organism
Variovorax paradoxus (strain S110)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
VPAR543728:G1GF3-528-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Type VI secretion system Vgr family proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Vapar_0531Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiVariovorax paradoxus (strain S110)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri543728 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeVariovorax
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000453 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
543728.Vapar_0531

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni505 – 528DisorderedSequence analysisAdd BLAST24
Regioni888 – 1003DisorderedSequence analysisAdd BLAST116

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili848 – 868Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi506 – 525PolarSequence analysisAdd BLAST20
Compositional biasi893 – 908PolarSequence analysisAdd BLAST16
Compositional biasi927 – 1003PolarSequence analysisAdd BLAST77

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VgrG protein family.ARBA annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG0744, Bacteria
COG3501, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004121_5_0_4

KEGG Orthology (KO)

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KOi
K11904

Identification of Orthologs from Complete Genome Data

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OMAi
ANYNEIM

Database of Orthologous Groups

More...
OrthoDBi
1880900at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.50.230, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017847, T6SS_RhsGE_Vgr_subset
IPR006533, T6SS_Vgr_RhsGE
IPR037026, Vgr_OB-fold_dom_sf

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01646, vgr_GE, 1 hit
TIGR03361, VI_Rhs_Vgr, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C5CK96-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADHEFRIET DSPAKDDLMF WRIVGHEALA RPSAYELTVL SKNKALDAKD
60 70 80 90 100
ILGRAFDVVI QFQDKDGGVH ERHCQGHAVR FVRAGHVGRH FEYRVTLRSW
110 120 130 140 150
FWLLTKRTNS RILQDKKVLE VLDAVFEDSP IKRFKKTKAG NVIGTHTPRR
160 170 180 190 200
YCVQHQENDY QFLSRLLEDE GIYYWFDAHD APGTMHLSDA SDLAHEKLPV
210 220 230 240 250
EGTLRYMSSD ASEARHNEIS RWVSARQFDT GKQASRDSDF KAIKKKLAAT
260 270 280 290 300
IDVKDDHELA DFEEFEFPGG YFTGDDGENR TKLRGDELNA RRDRHWALTT
310 320 330 340 350
WPDVAAGRSF KFEGDPDGTR NGDYVIAACT FMASHPGYES VGAGTAVPQD
360 370 380 390 400
LRTALAGVLR DDAVNADTLQ VLEDLIASTP MLSTSQPGTS AFLITAIPME
410 420 430 440 450
RAYRPPRLTP RVTMPGPQTA IVVGPAGDEL HVDEHGRVKV HFHWDRYDES
460 470 480 490 500
NEKSTCWVRV SQPWSGKGWG GYFIPRIGQE VIVDFINGDP DRPIVVGRVY
510 520 530 540 550
NDDQPIPYKS PTQSGFKTRS TPGGGPANYN EIMFEDKKGE ENINIHAERN
560 570 580 590 600
MSRSVERDDS TTVGRDQSLV VERDQSGIVQ RDQSLAVTRN RSIHVKNNES
610 620 630 640 650
HIVDVNQSLK VIGNQENKIV GNQVTTVDGV HQVEAKGDIR TKTSGNRIDH
660 670 680 690 700
TTGNETRKVS GNQTFTVSGN MGFKAATIVM ETPHFEWKIT GANSAVMAVP
710 720 730 740 750
SGPYSIMANK FSVLSNTDAS ILAVGKINQT SIENNVTVMG NNNSGYVGMA
760 770 780 790 800
SETNMGLARS TFLGVAIDTF MGASISNTLA LQFEAVAAAK LSIAVGPHIE
810 820 830 840 850
MNSMKMYVPG GGAAGGGATV LSEGAEFLAI VGVLEGVNVG FMSSVIGFAE
860 870 880 890 900
LSDQYSDAKA ELAQAARDAA AAGHPGLAAR LNRLATDGAG TMDKDAPTST
910 920 930 940 950
QNTRGDAFSS DYDPFAVPDG GSSSDPSAGG DGPTSSEPSS SEPSSSGPSS
960 970 980 990 1000
SEPTSSEPSS SEPSSSEPSS SEPSSSEPSS SGPSSSGPSS SEPNSSEPNS

SGF
Length:1,003
Mass (Da):108,452
Last modified:July 28, 2009 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD406CF4219620530
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP001635 Genomic DNA Translation: ACS17194.1

NCBI Reference Sequences

More...
RefSeqi
WP_012745694.1, NC_012791.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACS17194; ACS17194; Vapar_0531

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
45054858

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vap:Vapar_0531

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001635 Genomic DNA Translation: ACS17194.1
RefSeqiWP_012745694.1, NC_012791.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi543728.Vapar_0531

Genome annotation databases

EnsemblBacteriaiACS17194; ACS17194; Vapar_0531
GeneIDi45054858
KEGGivap:Vapar_0531

Phylogenomic databases

eggNOGiCOG0744, Bacteria
COG3501, Bacteria
HOGENOMiCLU_004121_5_0_4
KOiK11904
OMAiANYNEIM
OrthoDBi1880900at2

Enzyme and pathway databases

BioCyciVPAR543728:G1GF3-528-MONOMER

Family and domain databases

Gene3Di2.40.50.230, 1 hit
InterProiView protein in InterPro
IPR017847, T6SS_RhsGE_Vgr_subset
IPR006533, T6SS_Vgr_RhsGE
IPR037026, Vgr_OB-fold_dom_sf
TIGRFAMsiTIGR01646, vgr_GE, 1 hit
TIGR03361, VI_Rhs_Vgr, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC5CK96_VARPS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C5CK96
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: August 12, 2020
This is version 55 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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