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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei26SubstrateUniRule annotation1
Active sitei79NucleophileUniRule annotation1
Binding sitei128SubstrateUniRule annotation1
Binding sitei328SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciEICT634503:G1GVC-2969-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:NT01EI_3254
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002135131 – 348tRNA pseudouridine synthase DAdd BLAST348

Interactioni

Protein-protein interaction databases

STRINGi634503.NT01EI_3254

Structurei

3D structure databases

ProteinModelPortaliC5BGI9
SMRiC5BGI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 303TRUDUniRule annotationAdd BLAST150

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

C5BGI9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFSTLQYLH GRPVATGVVK AFAEDFFVAE DLGFTPDGEG EHVLVRLRKE
60 70 80 90 100
GCNTQFVAEN LARFARIAGR SVSYAGLKDR HAVTEQWFCL HLPGRDTPDF
110 120 130 140 150
SQFVLEGCQV LAVARHRKKL RIGTLRGNQF RLVLRHISDS AEVEERLRRV
160 170 180 190 200
ATQGVPNYFG EQRFGRGGNN LQQARRWATD QIRVKERAKR GFYLSAARSA
210 220 230 240 250
LFNLLVSERL AAGCFSRVLA GDALQLTGRG SWFVAREAEL SVLQQRLDVG
260 270 280 290 300
ELRITAALPG DGDGGVGGDA AEFERRVLSE TADLQALLTR ERVDPARRAV
310 320 330 340
LLQPQAMTWS WWDDATVELT FDLPAGSFAT SVVRELFCQE NSDADLAE
Length:348
Mass (Da):38,785
Last modified:July 28, 2009 - v1
Checksum:i626EB4D27487D262
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA Translation: ACR70395.1
RefSeqiWP_015872477.1, NC_012779.2

Genome annotation databases

EnsemblBacteriaiACR70395; ACR70395; NT01EI_3254
GeneIDi7961087
KEGGieic:NT01EI_3254
PATRICifig|634503.3.peg.2900

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA Translation: ACR70395.1
RefSeqiWP_015872477.1, NC_012779.2

3D structure databases

ProteinModelPortaliC5BGI9
SMRiC5BGI9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634503.NT01EI_3254

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR70395; ACR70395; NT01EI_3254
GeneIDi7961087
KEGGieic:NT01EI_3254
PATRICifig|634503.3.peg.2900

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Enzyme and pathway databases

BioCyciEICT634503:G1GVC-2969-MONOMER

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_EDWI9
AccessioniPrimary (citable) accession number: C5BGI9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: November 7, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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