UniProtKB - C5BDC2 (URE3_EDWI9)
Protein
Urease subunit gamma
Gene
ureA
Organism
Edwardsiella ictaluri (strain 93-146)
Status
Functioni
Catalytic activityi
- EC:3.5.1.5UniRule annotation
: urea degradation Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotationProteins known to be involved in this subpathway in this organism are:
- Urease subunit beta (ureB), Urease subunit alpha (ureC), Urease subunit gamma (ureA)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.
GO - Molecular functioni
- nickel cation binding Source: InterPro
- urease activity Source: UniProtKB-UniRule
GO - Biological processi
- urea catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Hydrolase |
Enzyme and pathway databases
BioCyci | EICT634503:G1GVC-1880-MONOMER |
UniPathwayi | UPA00258;UER00370 |
Names & Taxonomyi
Protein namesi | Recommended name: Urease subunit gammaUniRule annotation (EC:3.5.1.5UniRule annotation)Alternative name(s): Urea amidohydrolase subunit gammaUniRule annotation |
Gene namesi | Name:ureAUniRule annotation Ordered Locus Names:NT01EI_2063 |
Organismi | Edwardsiella ictaluri (strain 93-146) |
Taxonomic identifieri | 634503 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Hafniaceae › Edwardsiella › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000212801 | 1 – 100 | Urease subunit gammaAdd BLAST | 100 |
Interactioni
Subunit structurei
Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.
UniRule annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the urease gamma subunit family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_145825_1_0_6 |
OMAi | MQLTPHE |
OrthoDBi | 1826954at2 |
Family and domain databases
CDDi | cd00390, Urease_gamma, 1 hit |
Gene3Di | 3.30.280.10, 1 hit |
HAMAPi | MF_00739, Urease_gamma, 1 hit |
InterProi | View protein in InterPro IPR012010, Urease_gamma IPR002026, Urease_gamma/gamma-beta_su IPR036463, Urease_gamma_sf |
Pfami | View protein in Pfam PF00547, Urease_gamma, 1 hit |
PIRSFi | PIRSF001223, Urease_gamma, 1 hit |
SUPFAMi | SSF54111, SSF54111, 1 hit |
TIGRFAMsi | TIGR00193, urease_gam, 1 hit |
i Sequence
Sequence statusi: Complete.
C5BDC2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQLTPREVEK LMVYTLADVA LKRKQRGVKL NYPEAVSIIT VTAMEGARDG
60 70 80 90 100
KTVEEVMNEA RSVLTRDDVM DGVVELIPNV QVEAIFTDGS RLVTVHDPIQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001600 Genomic DNA Translation: ACR69239.1 |
RefSeqi | WP_015871371.1, NC_012779.2 |
Genome annotation databases
EnsemblBacteriai | ACR69239; ACR69239; NT01EI_2063 |
GeneIDi | 7961372 |
KEGGi | eic:NT01EI_2063 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP001600 Genomic DNA Translation: ACR69239.1 |
RefSeqi | WP_015871371.1, NC_012779.2 |
3D structure databases
SMRi | C5BDC2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | ACR69239; ACR69239; NT01EI_2063 |
GeneIDi | 7961372 |
KEGGi | eic:NT01EI_2063 |
Phylogenomic databases
HOGENOMi | CLU_145825_1_0_6 |
OMAi | MQLTPHE |
OrthoDBi | 1826954at2 |
Enzyme and pathway databases
UniPathwayi | UPA00258;UER00370 |
BioCyci | EICT634503:G1GVC-1880-MONOMER |
Family and domain databases
CDDi | cd00390, Urease_gamma, 1 hit |
Gene3Di | 3.30.280.10, 1 hit |
HAMAPi | MF_00739, Urease_gamma, 1 hit |
InterProi | View protein in InterPro IPR012010, Urease_gamma IPR002026, Urease_gamma/gamma-beta_su IPR036463, Urease_gamma_sf |
Pfami | View protein in Pfam PF00547, Urease_gamma, 1 hit |
PIRSFi | PIRSF001223, Urease_gamma, 1 hit |
SUPFAMi | SSF54111, SSF54111, 1 hit |
TIGRFAMsi | TIGR00193, urease_gam, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | URE3_EDWI9 | |
Accessioni | C5BDC2Primary (citable) accession number: C5BDC2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 22, 2009 |
Last sequence update: | July 28, 2009 | |
Last modified: | December 2, 2020 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families