Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA polymerase

Gene

PAS_chr2-2_0349

Organism
Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

Cofactori

[4Fe-4S] clusterUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotation
Ligand4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr2-2_0349Imported
OrganismiKomagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
Proteomesi
  • UP000000314 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi644223.XP_002491836.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 73DNA_pol_alpha_NInterPro annotationAdd BLAST67
Domaini340 – 686DNA_pol_B_exo1InterPro annotationAdd BLAST347
Domaini745 – 1192DNA_pol_BInterPro annotationAdd BLAST448
Domaini1235 – 1439zf-DNA_PolInterPro annotationAdd BLAST205

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Keywords - Domaini

Zinc-fingerUniRule annotation

Phylogenomic databases

eggNOGiKOG0970 Eukaryota
COG0417 LUCA
HOGENOMiHOG000163524
InParanoidiC4R232
KOiK02320
OMAiPKDCIFP
OrthoDBiEOG092C038B

Family and domain databases

Gene3Di1.10.3200.20, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 2 hits
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR017964 DNA-dir_DNA_pol_B_CS
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR024647 DNA_pol_a_cat_su_N
IPR023211 DNA_pol_palm_dom_sf
IPR038256 Pol_alpha_znc_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR015088 Znf_DNA-dir_DNA_pol_B_alpha
PfamiView protein in Pfam
PF12254 DNA_pol_alpha_N, 1 hit
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08996 zf-DNA_Pol, 1 hit
PRINTSiPR00106 DNAPOLB
SMARTiView protein in SMART
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS00116 DNA_POLYMERASE_B, 1 hit

Sequencei

Sequence statusi: Complete.

C4R232-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRTAKLKSL RAARSGINII SDHSDSEQDS YQLYDTVDEE EYRKRKRKEI
60 70 80 90 100
LEDDFIVDDN GEGYVDTGAD EWEGGYYDDQ DDNPDYDDQE NEDPLTTKHK
110 120 130 140 150
TKPKKVKQIN QFFTSTESKV KPVKSLKVDD ILNDFESKPT HAGSPFQVKS
160 170 180 190 200
GSKSTMFGGN KRAKLENTQK KKKVGLFSSE KKRKLNPSSS SIVNNDEINS
210 220 230 240 250
EDIERSIDVE QHLDQPKPDI KEMNSSPIKQ KVISLDQTQD EESDEELLIS
260 270 280 290 300
RRARTANTEI SREVNMRASV IEEKAADADS SSSPTRSRSI MTSSPSKVTK
310 320 330 340 350
LGGTDLSEGP VLMYWLDYVE VNHKLLLFGK VRTSSGALVS AMVQVGGVDR
360 370 380 390 400
EIYILPRSSH RSDSSAPCGP MDVHEEITPL LLEKYGLKSI RAKPVTMKYA
410 420 430 440 450
FELPGVPSEA DYLKILLPHD TPLNADLALP SSLEGETFQR VFGGHSALFE
460 470 480 490 500
DFVLQKDVMG PCWLEISNPD FDSMRNSSHC RVEMAIQSPK DITVYRGTDQ
510 520 530 540 550
TAPNLTVLGI TVQTVMNTRT NNQEVAAVSI ATFNELPQEL PIPEDLQPDE
560 570 580 590 600
LITLIRPLGD STVFPPGVQR AIEKQGLKIR CTPNEKTLLN LLCALVKRAD
610 620 630 640 650
PDVFVGHRIE SIQLDVLVHR LYDLKVPTWS SFGRLNKKVW PDRFPRRSGG
660 670 680 690 700
PSKVREIFHG RLLCDIGNDM GQSLTTKCQS WDLPEMYQSV CGKTFKPSEI
710 720 730 740 750
ALNNPQLSEN VNLLLTVAKE GASMVQITSE ITFRIQILSL SKILTNLAGN
760 770 780 790 800
AWSHTLGGTR AGRNEFILLH EFRKNGYIVP DKENFYQKHQ QQQLQDQSPE
810 820 830 840 850
DDETTKISSK KNNKFKGGLV FEPEKGLHRN IVLVLDFNSL YPSIIQEFNI
860 870 880 890 900
CFTTVERESG NVDTIPPVPV QNSQQGVLPR LLANLVSRRR EVKKLLKDSK
910 920 930 940 950
IGPVEKAQFD IKQQALKLTA NSMYGCLGYV NSRFYARPLA MLVTSKGREI
960 970 980 990 1000
LMDTRQLAES LGLKVVYGDT DSVMIDSGTI DYQEAIAIGE DLKAKVNERY
1010 1020 1030 1040 1050
SLLEIDIDNV FKRILLHAKK KYAAMNLSLQ NGKMVSQLEV KGLDMRRREY
1060 1070 1080 1090 1100
CQLSKEISTH VLEQILGEND SDEALSDIYQ YLETMGTKIR ENSIPITKFN
1110 1120 1130 1140 1150
INTKLSKDPA QYANAGGMPQ VQVALRLRGQ GKVVKAGTVV SFIVTAGDDN
1160 1170 1180 1190 1200
LSVAERARPL AEVLATPEQL RPDPDYYLEK QIFAPVERLV ERLEGVDLVR
1210 1220 1230 1240 1250
LAKCLGLDSG RYARIRTQYA NGGANGDDLL QPLESCISDA ERFKEAATLE
1260 1270 1280 1290 1300
LTCTCGAHFA FGGIQESSYY TVTFSGIQCS SCGTQLSSLR VASQLERLIR
1310 1320 1330 1340 1350
HHISLYYAGW VECDDVSCGV HTRQVSVYGK RCIGNTGRSV GCKGVISYVY
1360 1370 1380 1390 1400
TDRELYNQLL YLESLFDVDK ARRQELRPLQ DDTENRIRSD SGETKKGISQ
1410 1420 1430 1440
STLDALAEQN RDTFGAFQSV VQKYFEQCGR RYVDMASLFN FS
Length:1,442
Mass (Da):161,701
Last modified:July 7, 2009 - v1
Checksum:iA8350196D58D4B76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392320 Genomic DNA Translation: CAY69556.1
RefSeqiXP_002491836.1, XM_002491791.1

Genome annotation databases

EnsemblFungiiCAY69556; CAY69556; PAS_chr2-2_0349
GeneIDi8198249
KEGGippa:PAS_chr2-2_0349

Similar proteinsi

Entry informationi

Entry nameiC4R232_KOMPG
AccessioniPrimary (citable) accession number: C4R232
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: May 23, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health