Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 68 (11 Dec 2019)
Sequence version 2 (14 Dec 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Golgi-specific brefeldin A-resistance factor,putative

Gene

Smp_101280

Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Golgi-specific brefeldin A-resistance factor,putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Smp_101280Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchistosoma mansoni (Blood fluke)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6183 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6183.Smp_101280.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini503 – 693SEC7InterPro annotationAdd BLAST191

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1278 – 1308DisorderedSequence analysisAdd BLAST31
Regioni1627 – 1653DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1627 – 1646PolarSequence analysisAdd BLAST20

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0928 Eukaryota
COG5307 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230678

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
C4QNZ8

KEGG Orthology (KO)

More...
KOi
K18443

Database of Orthologous Groups

More...
OrthoDBi
815698at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
C4QNZ8

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00171 Sec7, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1000.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
IPR032691 Sec7_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01369 Sec7, 1 hit
PF12783 Sec7_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00222 Sec7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF48425 SSF48425, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50190 SEC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

C4QNZ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPSNALCMI QSEVSLMLTA LRCSHRNSFR MYQDDSKRPL LLSFNQLRSI
60 70 80 90 100
LNVAKSVNEL EPLVYLTPFL EVIRSEDTTG PVTGLALTAV DKFLSYGLLE
110 120 130 140 150
LPSSKSDESS LNKTGSLNSI GLAVEAIADA STQARFVGTD PRSAEVVLMK
160 170 180 190 200
VLHLLRTLLL VPAGALVSDR AIREILQSCF RICFEPKLSE LLRRTAELCL
210 220 230 240 250
ASMIQLFFSR LPTLVGFKTD RVVQQPTVQL ENSTMLSQPD TRSDDLQTVD
260 270 280 290 300
HQPQPYTIET VCELLSNLIH SLSPEHNKES VISISLGLIT IALETGADAI
310 320 330 340 350
ANSPRLLHLV RGDLTKYLML LLYSEDVWQF AATLRVCFLL FESMRSQLKL
360 370 380 390 400
QMEVYLQRLT AIISSDNEST GYERREIALD SVVRLFLVPG LAAELYINYD
410 420 430 440 450
CDPYCSNLFE DITKMLAKNA FPVVRLMGTH LLALDALLAV LNTIEVQCGA
460 470 480 490 500
SQATIIDQDS LNKSPNSTNY LPLVDKSSTI DSKYRVRPNR HFVDLTKLPS
510 520 530 540 550
REELNISKSK KKLLILGSDH FNIKPKRGIT FLQENDILQK PLNYDELALF
560 570 580 590 600
LRENPRLDKR MIGEYISDRE NTDVLTAFVR QFNFVGVPID EALRVYLEAF
610 620 630 640 650
RLPGEAPLIQ RIIEHFAEHW YTSNQSPFID VDAAFTLAYA ILMLNTDQHN
660 670 680 690 700
PNSKRQNAPM RMEDFKKNLS GMNGNQDFDP KLLESIYNNI HNHEIVMPIE
710 720 730 740 750
QTGLVRENYL WKCLLRRSST KQALFIHVQT GAFDADLFEL IWGPTVSALS
760 770 780 790 800
FIFDKTNDPE VQSKAIDGFN RCATIAAYYG MSDVLDNLVI SLCKFTTLLT
810 820 830 840 850
ANDNPTNLPI MLGRNTKACL ALYLVFTISS RHADILRYGW HSLLDCLLQL
860 870 880 890 900
FRANLLPNEL LESQDFLTTS RKVYITTKGC IPIKKESKNS RHSHRRRQKA
910 920 930 940 950
SRLQNSNSNR HLLSYVNRSQ LDEQTSSRFA SEIVIQCRID QLIEDSKFLV
960 970 980 990 1000
DASLTELIKV SLIQWTGNGN TSYYSSCNAT GVTSSDDCRV FCLELLIRVL
1010 1020 1030 1040 1050
MRNRDRLVCF WSLVRYYLVD LLLSARSPSL IVERVIVGFL RLAICLLRRH
1060 1070 1080 1090 1100
EVTSQVSFFA SSLSLLFKHG SRVARQVIGG LTDLLRNHAA DLPDPTTDWK
1110 1120 1130 1140 1150
LIFGLLEICG AGRRANILLT GTTVTKCDSE EKFSLASKSY SHLSSSNMFV
1160 1170 1180 1190 1200
SGNDGEQMQK KSSSEVIEQA ENDTTDVSES YEVIHKLPNK MAQITWGKSS
1210 1220 1230 1240 1250
LLISPLVLSY EVVIGSRDPV TLEQAVDCLA FLIRDPAHIT PDNFECAVEA
1260 1270 1280 1290 1300
LRVFVEACIN LPPRNANNLV SSSYDVNNKT ESAHRRRPDH PRHSTNRPNY
1310 1320 1330 1340 1350
ALSDSDTDTE QHLEYGKLKT VEKGVVFNIP ISLYFLKLLD LINILFTRAT
1360 1370 1380 1390 1400
SIYREWTRIN PGQLTSSTVV NEEFTNSQLD NEKYSHNNTN DVETSNSSMD
1410 1420 1430 1440 1450
SINLDHLWNV CWRPLLQSTA RLCSDIRRDV RTDALTYLQK ALLSPTLHLL
1460 1470 1480 1490 1500
NGKQWENCFN EVLFPLLSGF LESITLEEVL TTNSRNSHDI INYNTGYAHH
1510 1520 1530 1540 1550
LHAVEFADPR MRAIPLLTKV YLQHLRPLYE LDTFNTLWIR MLAYMEQYML
1560 1570 1580 1590 1600
ASSNSDSLTD AVRESLKNVL LVMCTGTHDI NPILIKDSPA NSNSAILWEL
1610 1620 1630 1640 1650
TEKHLSSFLP ELLEQLFPSN LPETNTTNVI TNSNDPPAIT ESNEELTHES
1660 1670 1680 1690 1700
SMSDDHINAV NQVLDVPTSR SPAESQLLND VNPSDIPVVV EQCSNHDINR
1710 1720
SSLELSEMTI SKPNISTIYN L
Length:1,721
Mass (Da):194,345
Last modified:December 14, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i46FB9C9714B84CCA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CABG01000147 Genomic DNA Translation: CAZ37185.2

NCBI Reference Sequences

More...
RefSeqi
XP_018644443.1, XM_018792472.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
Smp_101280.1; Smp_101280.1:pep; Smp_101280

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
Smp_101280.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8345501

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
smm:Smp_101280

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABG01000147 Genomic DNA Translation: CAZ37185.2
RefSeqiXP_018644443.1, XM_018792472.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi6183.Smp_101280.1

Genome annotation databases

EnsemblMetazoaiSmp_101280.1; Smp_101280.1:pep; Smp_101280
GeneDBiSmp_101280.1:pep
GeneIDi8345501
KEGGismm:Smp_101280

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8345501

Phylogenomic databases

eggNOGiKOG0928 Eukaryota
COG5307 LUCA
HOGENOMiHOG000230678
InParanoidiC4QNZ8
KOiK18443
OrthoDBi815698at2759
PhylomeDBiC4QNZ8

Family and domain databases

CDDicd00171 Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
IPR032691 Sec7_N
PfamiView protein in Pfam
PF01369 Sec7, 1 hit
PF12783 Sec7_N, 1 hit
SMARTiView protein in SMART
SM00222 Sec7, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF48425 SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50190 SEC7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC4QNZ8_SCHMA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: C4QNZ8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: December 14, 2011
Last modified: December 11, 2019
This is version 68 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again