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Protein

Deubiquitinase and deneddylase Dub1

Gene

cdu1

Organism
Chlamydia trachomatis serovar B (strain Jali20/OT)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease possesses deubiquitinating and deneddylating activities (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei288Sequence analysis1
Active sitei305Sequence analysis1
Active sitei358Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processUbl conjugation pathway, Virulence

Enzyme and pathway databases

BioCyciCTRA580049:G1GIO-964-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Deubiquitinase and deneddylase Dub1 (EC:3.4.22.-)
Short name:
ChlaDub1
Gene namesi
Name:cdu1
Ordered Locus Names:JALI_8791
OrganismiChlamydia trachomatis serovar B (strain Jali20/OT)
Taxonomic identifieri580049 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003964911 – 418Deubiquitinase and deneddylase Dub1Add BLAST418

Structurei

3D structure databases

SMRiC4PQR0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C48 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000034964
OMAiYFHTLYP

Family and domain databases

InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR003653 Peptidase_C48_C
PfamiView protein in Pfam
PF02902 Peptidase_C48, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit

Sequencei

Sequence statusi: Complete.

C4PQR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSPTNSISK TAPVPPQDSS KPVLISEEPQ NQLLQKVART ALAVLLVVVT
60 70 80 90 100
LGLILLFYSF SDLQSFPWCC QTRPSTKEQP TISIPVPLPS PPLAVPRPST
110 120 130 140 150
PPPPVISRPS TPPAPTPAIS PPSTPSAPKP STPPPLPPKA PKPVKTQEDL
160 170 180 190 200
LPFVPEQVFV EMYEDMARRR IIEALVPAWD SDIIFKCLCY FHTLYPGLIP
210 220 230 240 250
LETFPPATIF NFKQKIISIL EDKKAVLRGE PIKGSLPICC SEENYRRHLQ
260 270 280 290 300
GTTLLPVFMW YHPTPKTLSD TMQTMKQLAI KGSVGASHWL LVIVDIQARR
310 320 330 340 350
LVYFDSLYNY VMSPEDMKKD LQSFAQQLDQ VYPAYDSQIF SVKIAAKEVI
360 370 380 390 400
QKGSGSSCGA WCCQFLHWYL RDPFTDALND LPVDSVERHE NLASFVQACE
410
AAVQDLPELF WPEAKALF
Length:418
Mass (Da):46,632
Last modified:July 7, 2009 - v1
Checksum:iED7C51811337611B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM872308 Genomic DNA Translation: CAX11332.1
RefSeqiWP_012728021.1, NC_012686.1

Genome annotation databases

EnsemblBacteriaiCAX11332; CAX11332; JALI_8791
KEGGictj:JALI_8791

Similar proteinsi

Entry informationi

Entry nameiCDUB1_CHLTJ
AccessioniPrimary (citable) accession number: C4PQR0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: July 7, 2009
Last modified: June 20, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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