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Protein

Deubiquitinase and deneddylase Dub2

Gene

cdu2

Organism
Chlamydia trachomatis serovar B (strain Jali20/OT)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease possesses deubiquitinating and deneddylating activities (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei203Sequence analysis1
Active sitei220Sequence analysis1
Active sitei282Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processUbl conjugation pathway, Virulence

Enzyme and pathway databases

BioCyciCTRA580049:G1GIO-962-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Deubiquitinase and deneddylase Dub2 (EC:3.4.22.-)
Short name:
ChlaDub2
Gene namesi
Name:cdu2
Ordered Locus Names:JALI_8781
OrganismiChlamydia trachomatis serovar B (strain Jali20/OT)
Taxonomic identifieri580049 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 56HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003964981 – 339Deubiquitinase and deneddylase Dub2Add BLAST339

Proteomic databases

PRIDEiC4PQQ9

Structurei

3D structure databases

SMRiC4PQQ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C48 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000034963
OMAiECICNCL

Family and domain databases

InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR003653 Peptidase_C48_C
PfamiView protein in Pfam
PF02902 Peptidase_C48, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit

Sequencei

Sequence statusi: Complete.

C4PQQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPIHNPPPQ TCSYSRPSTT YTSFKDASCG TKVTRIIIAL FLIVISCGLI
60 70 80 90 100
LCAYTFRDLL DADYSAQEGP QQATKLLQQL DKVLTGPPLP IWDNEHLFQF
110 120 130 140 150
SCLMQNKHRR VLPIDICNPL TKFNFLEYIC NCLMTKQSVN VNETDMCELF
160 170 180 190 200
CPPTCTPENY RRLLCTSSVF PFVMWHDPSA DTQEAMLTKM DQTMSSGRVG
210 220 230 240 250
NSHWVLVIVD IEHRCVTFFD SFYNYIASPQ QMREQLEGLA ASLGAIYPKE
260 270 280 290 300
GGSDSDQEEL LSPFQVRIGS TVKVQSPGEF TCGAWCCQFL AWYLENPDFD
310 320 330
LEEKVPTNPS ERRALLADFI STTEQAMSRY SSLSWPTTD
Length:339
Mass (Da):38,426
Last modified:July 7, 2009 - v1
Checksum:iBE3EC2D7BE75E4FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM872308 Genomic DNA Translation: CAX11331.1
RefSeqiWP_012728020.1, NC_012686.1

Genome annotation databases

EnsemblBacteriaiCAX11331; CAX11331; JALI_8781
KEGGictj:JALI_8781

Similar proteinsi

Entry informationi

Entry nameiCDUB2_CHLTJ
AccessioniPrimary (citable) accession number: C4PQQ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: July 7, 2009
Last modified: June 20, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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