UniProtKB - C4P0A4 (C4P0A4_HUMAN)
Protein
Submitted name:
Disrupted in schizophrenia 1 isoform 16
Gene
DISC1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Disrupted in schizophrenia 1 isoform 16Imported |
Gene namesi | Name:DISC1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 24 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 179 – 205 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 221 – 257 | DisorderedSequence analysisAdd BLAST | 37 | |
Regioni | 278 – 323 | DisorderedSequence analysisAdd BLAST | 46 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 366 – 393 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 455 – 496 | Sequence analysisAdd BLAST | 42 | |
Coiled coili | 543 – 563 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 604 – 624 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 639 – 666 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysisFamily and domain databases
InterProi | View protein in InterPro IPR026081, DISC1 |
PANTHERi | PTHR14332, PTHR14332, 1 hit |
i Sequence
Sequence statusi: Complete.
C4P0A4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPGGGPQGAP AAAGGGGVSH RAGSRDCLPP AACFRRRRLA RRPGYMRSST
60 70 80 90 100
GPGIGFLSPA VGTLFRFPGG VSGEESHHSE SRARQCGLDS RGLLVRSPVS
110 120 130 140 150
KSAAAPTVTS VRGTSAHFGI QLRGGTRLPD RLSWPCGPGS AGWQQEFAAM
160 170 180 190 200
DSSETLDASW EAACSDGARR VRAAGSLPSA ELSSNSCSPG CGPEVPPTPP
210 220 230 240 250
GSHSAFTSSF SFIRLSLGSA GERGEAEGCP PSREAESHCQ SPQEMGAKAA
260 270 280 290 300
SLDGPHEDPR CLSRPFSLLA TRVSADLAQA ARNSSRPERD MHSLPDMDPG
310 320 330 340 350
SSSSLDPSLA GCGGDGSSGS GDAHSWDTLL RKWEPVLRDC LLRNRRQMEV
360 370 380 390 400
ISLRLKLQKL QEDAVENDDY DKAETLQQRL EDLEQEKISL HFQLPSRQPA
410 420 430 440 450
LSSFLGHLAA QVQAALRRGA TQQASGDDTH TPLRMEPRLL EPTAQDSLHV
460 470 480 490 500
SITRRDWLLQ EKQQLQKEIE ALQARMFVLE AKDQQLRREI EEQEQQLQWQ
510 520 530 540 550
GCDLTPLVGQ LSLGQLQEVS KALQDTLASA GQIPFHAEPP ETIRSLQERI
560 570 580 590 600
KSLNLSLKEI TTKVCMSEKF CSTLRKKVND IETQLPALLE AKMHAISGNH
610 620 630 640 650
FWTAKDLTEE IRSLTSEREG LEGLLSKLLV LSSRNVKKLG SVKEDYNRLR
660 670 680
REVEHQETAY ETSVKENTMK YMETLKNKLC R
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FJ804187 mRNA Translation: ACR40053.1 |
RefSeqi | NP_001158014.1, NM_001164542.1 |
Genome annotation databases
GeneIDi | 27185 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FJ804187 mRNA Translation: ACR40053.1 |
RefSeqi | NP_001158014.1, NM_001164542.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | C4P0A4 |
PeptideAtlasi | C4P0A4 |
Protocols and materials databases
DNASUi | 27185 |
Genome annotation databases
GeneIDi | 27185 |
Organism-specific databases
CTDi | 27185 |
PharmGKBi | PA27342 |
Miscellaneous databases
BioGRID-ORCSi | 27185, 5 hits in 986 CRISPR screens |
GenomeRNAii | 27185 |
Gene expression databases
Genevisiblei | C4P0A4, HS |
Family and domain databases
InterProi | View protein in InterPro IPR026081, DISC1 |
PANTHERi | PTHR14332, PTHR14332, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | C4P0A4_HUMAN | |
Accessioni | C4P0A4Primary (citable) accession number: C4P0A4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 7, 2009 |
Last sequence update: | July 7, 2009 | |
Last modified: | April 7, 2021 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |